11,357 results match your criteria: "Hepatic Stellate Cells"

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Brevilin A is a potent anti-metastatic CRC agent that targets the VEGF-IL6-STAT3 axis in the HSCs-CRC interplay.
Xueying Fan, Mingjing Meng, Baoting Li, Hui Chen, Jincheng Tan

J Transl Med· April 2023

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The liver.
Elijah Trefts, Maureen Gannon, David H Wasserman

Curr Biol· November 2017

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Effect of TGFβ-ITGB6 feedback loop on liver metastasis in SMAD4 wild-type pancreatic cancer.
Yutong Zhao, Cheng Qin, Bangbo Zhao, Zeru Li, Tianyu Li

Chin Med J (Engl)· December 2025

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Fibrosis-driven hepatocarcinogenesis, metastasis and immune evasion: Mechanisms and therapeutic targets.
Zilong Zhang, Xiaoping Chen, Bixiang Zhang, Wanguang Zhang, Ze-Yang Ding

Biochim Biophys Acta Rev Cancer· December 2025

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Protopine attenuates hepatic fibrosis via HDAC6-mediated NLRP3 inflammasome activation.
Yamei Li, Minyan Liang, Xinjing Wang, Qinghua Zhu, Jing Nie

Bioorg Chem· December 2025

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Effect of free fatty acids on TGF-β1 mediated fibrogenesis in hepatic stellate cells.
William De Nardo, Jacqueline Bayliss, Sheik Nadeem Elahee Doomun, Olivia Lee, Paula M Miotto

Mol Metab· December 2025

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HKDC1 promotes the H3K18 lactylation of the promoter of ORMDL3 to induce the activation of hepatic stellate cells in liver cirrhosis.
Yanan Zhang, Lei Li, Gaiqin Li, Junyuan Zhu, Zexue Qi

Biochim Biophys Acta Mol Basis Dis· December 2025

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Naringenin attenuates liver injury in Schistosoma mansoni-induced liver fibrosis and oxidative stress in mice model.
Ting-Ruei Liang, Chao-Zong Liu, Shih-Yi Peng

PLoS Negl Trop Dis· December 2025

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Obtusifolin mitigates CCl-induced inflammation and liver fibrosis by modulating the ROCK2/ Cofilin-1 / NFκB pathway.
Suriya Panneerselvam, Nidhi Sharma, Sai Balaji Andugulapati

Eur J Pharmacol· December 2025

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Hyperoside attenuates NASH-associated liver fibrosis by modulating Flot2/TLR4 signaling and pyroptosis.
Peng Huang, Yunling Zhu, Zhiling Li, Kaixuan Zeng, Lang Qin

Int Immunopharmacol· December 2025

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Hydrophilic and lipophilic colchicinoid formulations for therapy of liver fibrosis in murine model.
Elena V Svirshchevskaya, Ekaterina S Shchegravina, Iuliia A Gracheva, Maryia V Konovalova, Sergei B Akopov

Bioorg Chem· December 2025

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Emerging role of FUS in TGFB1 and COL1A1 transcription dependent on GADD45B to induce NASH-fibrosis.
Chi Wu, Qiang Ding, Zhilin Zeng, Longjun Yang, Xiaozhen Song

J Mol Cell Biol· December 2025

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AI-aided identification of dual-purpose therapeutic targets PRPF19 and MAPK9 in hepatocellular carcinoma and cellular senescence.
Christopher Ren, Geoffrey Ho Duen Leung, Qiuqiong Tang, Peiran Zhang, Yongming Ma

NPJ Aging· December 2025

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Imperfect Repair in Aging: Senescent Cells and the Hepatic Fibrotic Niche.
Juyeon Kim, Minseong Kim, Chuna Kim

BMB Rep· December 2025

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Exosomes From Hepatitis B Virus-Infected Hepatocytes Induce Liver Fibrosis Through METTL3-Mediated m6A Modification of P2RX7 mRNA.
Caixia Li, Jiaxin Zeng, Yongbo Liu, Zhibin Chen

J Biochem Mol Toxicol· December 2025

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Myeloid CD36 deficiency alleviates hepatic fibrosis by promoting adaptive immunity of macrophage.
Liangyun Li, Yilong Fang, Jintong Zhang, Mengmeng Song, Sijin Sun

Hepatology· December 2025

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An α-specific PI3K inhibitor improves chemotherapy efficacy by inhibiting hepatic stellate cell activation in liver cancer.
Qi Ruan, Tao Chen, Minwoo Kim, Haotian Yang, Debottam Sinha

Hepatology· December 2025

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Computational Integration of In Vivo Single Cell and In Vitro Bulk Transcriptomics Across 236 Human and Mouse Datasets Differentiates Physiological versus Non-Physiological Hepatic Cell Lines for Hepatotoxicity Screening.
Thomas Kowal, Susanna Wang, Michael Cheng, Ruoshui Liu, Montgomery Blencowe

Toxicol Sci· December 2025

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Jiayan Yan, Ao Huang, Shiyu Zhang, Na Yao, Junfeng Huang

Gut· December 2025

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Curcumol ameliorates high-fat diet-induced hepatic fibrosis via dual regulation of FXR-CREB and Rab18-mediated hepatic stellate cell lipophagy.
Na Wei, Wanyu Feng, Meijun Pan, Xinyi Xu, Shuguo Zheng

Biochim Biophys Acta Mol Cell Biol Lipids· December 2025

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PDGFRß targeted positron emission tomography as a non-invasive biomarker for activated hepatic stellate cells: lasts steps before clinical translation.
Chittampalli N Yashaswini, Bogdan Mitran, Natalia Papadopoulos, Olivia Wegrzyniak, John Löfblom

EJNMMI Radiopharm Chem· December 2025

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Targeting RNA Polymerase I Inhibits Ribosome Biogenesis to Block Liver Fibrosis Progression.
Wei Luo, Lixian Yi, Yu Zhang, Jing Zhou, Shihui Li

Liver Int· January 2026

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Osteopontin: a central hub in the pathogenesis and therapeutic intervention of liver disease.
Junran Yang, Yufei Yao, Zhenhua Zhou

Ann Med· December 2025

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Cichoriin suppresses hepatic lipid accumulation and fibrosis in mice metabolic dysfunction associated steatohepatitis via the AMPK pathway.
Yao Zhao, Xinjie Luo, Tian Li, Xinling Wang, Jianhua Yang

Biochem Pharmacol· December 2025

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A novel cell-permeable LOXL2 inhibitor PAT-1251 potently suppresses biliary liver fibrosis via collagen crosslinking-dependent and -independent mechanisms.
Ping An, Guangyan Wei, Pinzhu Huang, Heansika Matta, Wenda Li

Hepatol Commun· January 2026

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Cell-specific roles of autophagy in liver fibrosis: implications for targeted pharmacotherapy.
Chibo Liu, Huan Yang, Yongjie Liu, Min An, Zhiyong Weng

Ann Med· December 2025

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CXCR6 defines a distinct resident state in γδ T cells for protecting from liver cirrhosis.
Jiahao Ji, Zhitao Chen, Wenjing He, Yanxu Chen, Dongmei Ye

Hepatology· December 2025

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Protocol to isolate quiescent hepatic stellate cells in sufficient yield while maintaining cytokine responsiveness from aged female mice.
Takao Seki, Sachiko Komazawa-Sakon, Yuichi Tsuchiya, Kyoko Fukuhara, Yasuhiro Nakano

STAR Protoc· December 2025

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cortex alleviates fibrosis in hiPSC-derived multilineage hepatic organoids via the cAMP-PKA pathway.
Junming Xu, Xiaopu Sang, Yongfei He, Jie Ke, Jiasen Xu

Front Pharmacol· December 2025

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