Publications by authors named "Tim Heise"

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A Randomized Controlled Clinical Trial in Healthy Older Adults to Determine Efficacy of Glycine and N-Acetylcysteine Supplementation on Glutathione Redox Status and Oxidative Damage.
Giulia Lizzo, Eugenia Migliavacca, Daniela Lamers, Adrien Frézal, John Corthesy, Gerard Vinyes-Parès, Nabil Bosco, Leonidas G Karagounis, Ulrike Hövelmann, Tim Heise

Front Aging· March 2022

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Randomized investigation of heart failure therapy in patients with advanced cancer at risk of cardiac wasting: Rationale and design of the EMPATICC trial.
Markus S Anker, Amir A Mahabadi, Matthias Totzeck, Mitra Tewes, Raluca Mincu, Tim Heise

Eur J Heart Fail· October 2025

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Evaluating the Adequacy of Coefficient of Variation and Standard Deviation as Metrics of Glucose Variability in Type 1 Diabetes Based on Data from the GOLD and SILVER Trials.
Pavel Fatulla, Henrik Imberg, Sofia Sterner Isaksson, Irl B Hirsch, Johan Mårtensson, Tim Heise

Diabetes Technol Ther· August 2025

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[Type 1 Diabetes and Sports: What to Consider?].
Johanna Kramme, Othmar Moser, Tim Heise, Dominik Pesta

Dtsch Med Wochenschr· August 2025

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Heart Failure Therapy in Patients with Advanced Cancer Receiving Specialized Palliative Care (EMPATICC trial).
Markus S Anker, Amir A Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Shahzeb Khan, Tim Heise

Eur Heart J· August 2025

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Once-Weekly Insulins.
J Hans DeVries, Tim Heise

Diabetes Technol Ther· July 2025

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Biosimilar insulins: Narrative review of the regulatory framework and registration studies.
Tim Heise, J Hans DeVries

Diabetes Obes Metab· July 2025

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Greater improvement in insulin sensitivity per unit weight loss associated with tirzepatide versus semaglutide: An exploratory analysis.
Kieren J Mather, Andrea Mari, Govinda Weerakkody, Tim Heise, J Hans DeVries

Diabetes Obes Metab· March 2025

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Absence of a glucose-lowering effect in glucose clamp procedures with a long-acting insulin analogue.
J Hans DeVries, Sascha Heckermann, Tim Heise

Diabetes Obes Metab· December 2024

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Effects of Tirzepatide vs Semaglutide on β-Cell Function, Insulin Sensitivity, and Glucose Control During a Meal Test.
Kieren J Mather, Andrea Mari, Tim Heise, J Hans DeVries, Ming Hua

J Clin Endocrinol Metab· November 2024

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ADO09, a co-formulation of pramlintide and insulin A21G, lowers body weight versus insulin lispro in type 1 diabetes.
Grit Andersen, Rosy Eloy, Tim Heise, Martin Gaudier, Claire Mégret

Diabetes Obes Metab· October 2024

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The effect of AZD9567 vs. prednisolone on glycaemic control in patients with type 2 diabetes mellitus: Results from a phase 2a clinical trial.
Philip Ambery, Grzegorz Zajac, Joachim Almquist, Susanne Prothon, Carol Astbury, Tim Heise

Br J Clin Pharmacol· August 2024

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Frequency and Severity of Hypoglycemia Under Conditions of Increased Hypoglycemic Risk with Insulin Efsitora Alfa Versus Insulin Glargine Treatment in Participants with Type 2 Diabetes.
Tim Heise, Grit Andersen, Edward J Pratt, Jennifer Leohr, Tsuyoshi Fukuda

Diabetes Ther· August 2024

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Pharmacokinetic and pharmacodynamic properties of once-weekly insulin icodec in individuals with type 1 diabetes.
Ulrike Hövelmann, Susanne Engberg, Tim Heise, Niels Rode Kristensen, Lea Nørgreen

Diabetes Obes Metab· May 2024

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Pharmacokinetic and pharmacodynamic bioequivalence of Gan & Lee insulin analogues aspart (rapilin®), lispro (prandilin®) and glargine (basalin®) with EU- und US-sourced reference insulins.
Wei Chen, Jia Lu, Leona Plum-Mörschel, Grit Andersen, Eric Zijlstra, Tim Heise

Diabetes Obes Metab· December 2023

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Pharmacodynamics, safety, tolerability and pharmacokinetics of a single oral dose of an engineered phenylalanine ammonia-lyase in patients with phenylketonuria.
Timothy Nicholas Fazio, Louise Healy, Tim Heise, Anita Inwood, Catherine Manolikos

Mol Genet Metab Rep· December 2023

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Randomized Trial Comparing SGLT2 Inhibition and Hydrochlorothiazide on Sympathetic Traffic in Type 2 Diabetes.
Karsten Heusser, Jens Tank, André Diedrich, Annelie Fischer, Tim Heise

Kidney Int Rep· November 2023

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A co-formulation of pramlintide and insulin A21G (ADO09) improves postprandial glucose and short-term control of mean glucose, time in range, and body weight versus insulin aspart in adults with type 1 diabetes.
Grit Andersen, Rosy Eloy, Susanne Famulla, Tim Heise, Grégory Meiffren

Diabetes Obes Metab· May 2023

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Tirzepatide Reduces Appetite, Energy Intake, and Fat Mass in People With Type 2 Diabetes.
Tim Heise, J Hans DeVries, Shweta Urva, Jing Li, Edward J Pratt

Diabetes Care· May 2023

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Pharmacokinetic and pharmacodynamic properties of the novel basal insulin Fc (insulin efsitora alfa), an insulin fusion protein in development for once-weekly dosing for the treatment of patients with diabetes.
Tim Heise, Jenny Chien, John M Beals, Charles Benson, Oliver Klein

Diabetes Obes Metab· April 2023

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Oral insulin: A history of ambition, failure and data torturing.
Tim Heise, Leona Plum-Mörschel, Eric Zijlstra

Diabetes Obes Metab· April 2023

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Safety, tolerability, pharmacodynamics and pharmacokinetics following once-daily doses of BI 187004, an inhibitor of 11 beta-hydroxysteroid dehydrogenase-1, over 28 days in patients with type 2 diabetes mellitus and overweight or obesity.
Susanna Bianzano, Matias Nordaby, Leona Plum-Mörschel, Barbara Peil, Tim Heise

Diabetes Obes Metab· March 2023

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Limited evidence for sympathetic neural overactivation in older patients with type 2 diabetes mellitus.
Karsten Heusser, Jens Tank, André Diedrich, Annelie Fischer, Tim Heise

Front Neurosci· January 2023

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Selective Inhibition of 11beta-Hydroxysteroiddehydrogenase-1 with BI 187004 in Patients with Type 2 Diabetes and Overweight or Obesity: Safety, Pharmacokinetics, and Pharmacodynamics After Multiple Dosing Over 14 Days.
Susanna Bianzano, Cornelia Schepers, Michael Wolff, Tim Heise, Leona Plum-Moerschel

Exp Clin Endocrinol Diabetes· December 2022

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Association of HbA1c with VO in Individuals with Type 1 Diabetes: A Systematic Review and Meta-Analysis.
Max L Eckstein, Felix Aberer, Florian J R Dobler, Faisal Aziz, Tim Heise

Metabolites· October 2022

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