Publications by authors named "Xihong Lin"

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Nonsteroidal Antiinflammatory Drugs Modify the Effect of Short-Term Air Pollution on Lung Function.
Xu Gao, Brent Coull, Xihong Lin, Pantel Vokonas, Joel Schwartz, Andrea A Baccarelli

Am J Respir Crit Care Med· February 2020

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Streamlining large-scale genomic data management: Insights from the UK Biobank whole-genome sequencing data.
Xihao Li, Andrew R Wood, Yuxin Yuan, Manrui Zhang, Yushu Huang, Xihong Lin, Zilin Li

Cell Genom· December 2025

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FAVOR 2.0: A reengineered functional annotation of variants online resource for interpreting genomic variation.
Hufeng Zhou, Vineet Verma, Xihao Li, Zilin Li, Nicole Shedd, Xihong Lin

Nucleic Acids Res· December 2025

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Multi-omics analysis reveals differential benefits of immunotherapy±chemotherapy based on detailed smoking history in advanced non-small cell lung cancer.
Xinan Wang, Biagio Ricciuti, Arielle Elkrief, Joao V Alessi, Alessandro Di Federico, Xihong Lin

J Immunother Cancer· December 2025

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SEEK-VEC: Robust Latent Structure Discovery via Ensemble Topic Modeling.
Rebecca Danning, Zheng Tracy Ke, Rong Ma, Xihong Lin

bioRxiv· December 2025

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Trajectory-informed gene feature selection in single-cell analysis with SEEK-VFI.
Rebecca Danning, Zheng Tracy Ke, Xihong Lin, Rong Ma

bioRxiv· December 2025

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cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions.
Eric Van Buren, Yi Zhang, Xihao Li, Margaret Sunitha Selvaraj, Zilin Li, Susan Redline, Xihong Lin

Nat Methods· December 2025

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Effects of an app-based brief gratitude practice on positive and negative daily affect during the COVID-19 pandemic.
Shengjie Lin, Shuting Shen, Zorana Ivcevic, David R Cheng, Ryan Probasco, Xihong Lin

Acta Psychol (Amst)· October 2025

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Whole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals.
Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, Eric Van Buren, Sara Haidermota, Patrick T Ellinor, Susan Redline, Xihong Lin

Genome Biol· September 2025

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Genome-wide association study for lung cancer in 6531 African Americans reveals new susceptibility loci.
Jinyoung Byun, Younghun Han, Jiyeon Choi, Ryan Sun, Vikram R Shaw, Linda Kachuri, Angeline S Andrew, Melinda C Aldrich, Xihong Lin

Hum Mol Genet· July 2025

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Advancing real-time infectious disease forecasting using large language models.
Hongru Du, Yang Zhao, Jianan Zhao, Shaochong Xu, Xihong Lin

Nat Comput Sci· June 2025

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Linking sleep microstructure, blood markers of inflammation and metabolism, and cognition: mediation analysis in the osteoporotic fractures in men study.
Claire Suen, Julia Ma, Xihong Lin, Robert J Thomas, M Brandon Westover, Susan Redline

Geroscience· June 2025

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Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.
Xinruo Zhang, Jennifer A Brody, Mariaelisa Graff, Heather M Highland, Nathalie Chami, Zilin Li, Caitlin P McHugh, Xihong Lin

Nat Commun· April 2025

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LACE-UP: An ensemble machine-learning method for health subtype classification on multidimensional binary data.
Rebecca Danning, Frank B Hu, Xihong Lin

Proc Natl Acad Sci U S A· April 2025

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Genome-wide association study of early-stage non-small cell lung cancer prognosis: a pooled analysis in the International Lung Cancer Consortium.
Mei Dong, Abhinav Thakral, Karl Smith- Byrne, Yohan Bosse, Hufeng Zhou, Angeline S Andrew, Xihong Lin

Carcinogenesis· April 2025

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FABP4 as a therapeutic host target controlling SARS-CoV-2 infection.
Hatoon Baazim, Emre Koyuncu, Gürol Tuncman, M Furkan Burak, Lea Merkel, Katalin Földes, Xihong Lin

EMBO Mol Med· March 2025

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Causal Mediation Analysis for Integrating Exposure, Genomic, and Phenotype Data.
Haoyu Yang, Zhonghua Liu, Ruoyu Wang, En-Yu Lai, Joel Schwartz, Xihong Lin

Annu Rev Stat Appl· March 2025

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A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies.
Xihao Li, Han Chen, Margaret Sunitha Selvaraj, Eric Van Buren, Hufeng Zhou, Honghuang Lin, Susan Redline, Zilin Li, Xihong Lin

Nat Comput Sci· February 2025

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Streamlining Large-Scale Genomic Data Management: Insights from the UK Biobank Whole-Genome Sequencing Data.
Xihao Li, Andrew R Wood, Yuxin Yuan, Manrui Zhang, Yushu Huang, Xihong Lin, Zilin Li

medRxiv· January 2025

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Genomic insights for personalised care in lung cancer and smoking cessation: motivating at-risk individuals toward evidence-based health practices.
Tony Chen, Giang Pham, Louis Fox, Nina Adler, Xiaoyu Wang, Xihong Lin

EBioMedicine· December 2024

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Testing a Large Number of Composite Null Hypotheses Using Conditionally Symmetric Multidimensional Gaussian Mixtures in Genome-Wide Studies.
Ryan Sun, Zachary R McCaw, Xihong Lin

J Am Stat Assoc· December 2024

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Scalable analysis of large multi-ancestry biobanks by leveraging sparse ancestry-adjusted sample-relatedness.
Xihong Lin, Rounak Dey, Xihao Li, Zilin Li

Res Sq· November 2024

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Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height.
Gareth Hawkes, Robin N Beaumont, Zilin Li, Ravi Mandla, Xihao Li, Patrick T Ellinor, Susan Redline, Timothy M Frayling, Caroline F Wright, Xihong Lin

Nat Commun· October 2024

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SPLENDID incorporates continuous genetic ancestry in biobank-scale data to improve polygenic risk prediction across diverse populations.
Tony Chen, Haoyu Zhang, Rahul Mazumder, Xihong Lin

bioRxiv· October 2024

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FAVOR-GPT: a generative natural language interface to whole genome variant functional annotations.
Thomas Cheng Li, Hufeng Zhou, Vineet Verma, Xiangru Tang, Yanjun Shao, Xihong Lin

Bioinform Adv· September 2024

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Ensemble methods for testing a global null.
Yaowu Liu, Zhonghua Liu, Xihong Lin

J R Stat Soc Series B Stat Methodol· April 2024

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