Publications by authors named "AM Gorman"

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Multiomics Integration of Parkinson's Disease Datasets Reveals Unexpected Roles of IRE1 in Its Pathology.
Bianka Alexandra Pasat, Matthieu Moncan, Eleftherios Pilalis, Afshin Samali, Aristotelis Chatziioannou, Adrienne M Gorman

Int J Mol Sci· July 2025

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MultiOmicsIntegrator: a nextflow pipeline for integrated omics analyses.
Bianka Alexandra Pasat, Eleftherios Pilalis, Katarzyna Mnich, Afshin Samali, Aristotelis Chatziioannou, Adrienne M Gorman

Bioinform Adv· November 2024

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Insights into the structure and function of the RNA ligase RtcB.
Matthieu Moncan, Hassan Rakhsh-Khorshid, Leif A Eriksson, Afshin Samali, Adrienne M Gorman

Cell Mol Life Sci· November 2023

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Endoplasmic Reticulum Stress-Regulated Chaperones as a Serum Biomarker Panel for Parkinson's Disease.
Katarzyna Mnich, Shirin Moghaddam, Patrick Browne, Timothy Counihan, Stephen P Fitzgerald, Adrienne M Gorman

Mol Neurobiol· March 2023

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Tracking Fish Lifetime Exposure to Mercury Using Eye Lenses.
Hadis Miraly, N Roxanna Razavi, Annabelle A Vogl, Richard T Kraus, Ann Marie Gorman

Environ Sci Technol Lett· March 2023

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Inhibition of IRE1α RNase activity sensitizes patient-derived acute myeloid leukaemia cells to proteasome inhibitors.
Stuart Creedican, Claire M Robinson, Katarzyna Mnich, Md Nahidul Islam, Eva Szegezdi, Adrienne M Gorman

J Cell Mol Med· August 2022

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New insights into IRE1α activation and function in anti-tumor immunity.
Susan E Logue, Adrienne M Gorman, Afshin Samali

J Cell Biol· June 2022

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Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer.
Aitor Almanza, Katarzyna Mnich, Arnaud Blomme, Claire M Robinson, Giovanny Rodriguez-Blanco, Adrienne M Gorman

Nat Commun· May 2022

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Functional traits reveal the dominant drivers of long-term community change across a North American Great Lake.
James S Sinclair, Michael E Fraker, James M Hood, Kenneth T Frank, Mark R DuFour, Ann Marie Gorman

Glob Chang Biol· December 2021

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The stressosome, a caspase-8-activating signalling complex assembled in response to cell stress in an ATG5-mediated manner.
Katarzyna Mnich, Izabela Koryga, Karolina Pakos-Zebrucka, Melissa Thomas, Susan E Logue, Adrienne M Gorman

J Cell Mol Med· September 2021

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Regulation of lipid metabolism by the unfolded protein response.
Matthieu Moncan, Katarzyna Mnich, Arnaud Blomme, Aitor Almanza, Afshin Samali, Adrienne M Gorman

J Cell Mol Med· February 2021

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An Emerging Role for the Unfolded Protein Response in Pancreatic Cancer.
Claire M Robinson, Aaron Talty, Susan E Logue, Katarzyna Mnich, Adrienne M Gorman

Cancers (Basel)· January 2021

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Local intracerebral inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo.
Pierre Jean Le Reste, Raphael Pineau, Konstantinos Voutetakis, Juhi Samal, Gwénaële Jégou, Adrienne M Gorman

Cancer Lett· December 2020

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The IRE1 and PERK arms of the unfolded protein response promote survival of rhabdomyosarcoma cells.
Nicole McCarthy, Nadezda Dolgikh, Susan Logue, John B Patterson, Qinping Zeng, Adrienne M Gorman

Cancer Lett· October 2020

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Novel Pt(IV) Prodrugs Displaying Antimitochondrial Effects.
Leila Tabrizi, Kerry Thompson, Katarzyna Mnich, Chetan Chintha, Adrienne M Gorman

Mol Pharm· August 2020

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Tumour Cell Secretome in Chemoresistance and Tumour Recurrence.
Emma C Madden, Adrienne M Gorman, Susan E Logue, Afshin Samali

Trends Cancer· June 2020

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Time and region-dependent manner of increased brain derived neurotrophic factor and TrkB in rat brain after binge-like methamphetamine exposure.
Andreia Moreira da Silva Santos, Adrienne M Gorman, John P Kelly, Karen M Doyle

Neurosci Lett· January 2020

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Correction: Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β.
Aaron Talty, Shane Deegan, Mila Ljujic, Katarzyna Mnich, Serika D Naicker, Adrienne M Gorman

Cell Death Dis· January 2020

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Crosstalk between inflammatory mediators and endoplasmic reticulum stress in liver diseases.
J Catharina Duvigneau, Andreia Luís, Adrienne M Gorman, Afshin Samali, Doris Kaltenecker

Cytokine· December 2019

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Molecular modeling provides a structural basis for PERK inhibitor selectivity towards RIPK1.
Chetan Chintha, Antonio Carlesso, Adrienne M Gorman, Afshin Samali, Leif A Eriksson

RSC Adv· December 2019

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Effect of Kinase Inhibiting RNase Attenuator (KIRA) Compounds on the Formation of Face-to-Face Dimers of Inositol-Requiring Enzyme 1: Insights from Computational Modeling.
Antonio Carlesso, Chetan Chintha, Adrienne M Gorman, Afshin Samali, Leif A Eriksson

Int J Mol Sci· November 2019

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Application of a New Multiplexed Array for Rapid, Sensitive, Simultaneous and Quantitative Assessment of Spliced and Unspliced XBP1.
Stuart Creedican, Aaron Talty, Stephen P Fitzgerald, Afshin Samali, Ciarán Richardson, Adrienne M Gorman

Biol Proced Online· November 2019

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Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β.
Aaron Talty, Shane Deegan, Mila Ljujic, Katarzyna Mnich, Serika D Naicker, Adrienne M Gorman

Cell Death Dis· August 2019

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Merits and pitfalls of conventional and covalent docking in identifying new hydroxyl aryl aldehyde like compounds as human IRE1 inhibitors.
Antonio Carlesso, Chetan Chintha, Adrienne M Gorman, Afshin Samali, Leif A Eriksson

Sci Rep· March 2019

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Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain.
Antonio Carlesso, Chetan Chintha, Adrienne M Gorman, Afshin Samali, Leif A Eriksson

ACS Omega· October 2018

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