Publications by authors named "Adam Sharples"

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Response of UBR-box E3 ubiquitin ligases and protein quality control pathways to perturbations in protein synthesis and skeletal muscle size.
Leslie M Baehr, Luis Gustavo Oliveira de Sousa, Craig A Goodman, Adam P Sharples, David S Waddell

Am J Physiol Cell Physiol· December 2025

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Response of UBR-box E3 ubiquitin ligases and protein quality control pathways to perturbations in protein synthesis and skeletal muscle size.
Leslie M Baehr, Luis Gustavo Oliveira de Sousa, Craig A Goodman, Adam P Sharples, David S Waddell

bioRxiv· October 2025

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Molecular landscape of sex- and modality-specific exercise adaptation in human skeletal muscle through large-scale multi-omics integration.
Macsue Jacques, Shanie Landen, Adam P Sharples, Andrew Garnham, Ralf Schittenhelm

Cell Rep· June 2025

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Human skeletal muscle possesses both reversible proteomic signatures and a retained proteomic memory after repeated resistance training.
Juha J Hulmi, Eeli J Halonen, Adam P Sharples, Thomas M O'Connell, Lauri Kuikka

J Physiol· May 2025

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Epigenome-proteome integration in aged skeletal muscle after exercise training.
Adam P Sharples

J Physiol· January 2025

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Human skeletal muscle possesses an epigenetic memory of high-intensity interval training.
Andrea M Pilotto, Daniel C Turner, Raffaele Mazzolari, Emanuela Crea, Lorenza Brocca, Adam P Sharples

Am J Physiol Cell Physiol· January 2025

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A multi-epigenomic map of endurance exercise training.
Adam P Sharples

Trends Genet· September 2024

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Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle.
Sarah Voisin, Kirsten Seale, Macsue Jacques, Shanie Landen, Nicholas R Harvey, Adam P Sharples

Aging Cell· January 2024

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Correction: Effects of Aerobic Exercise on Cardiorespiratory Fitness, Cardiovascular Risk Factors, and Patient-Reported Outcomes in Long-Term Breast Cancer Survivors: Protocol for a Randomized Controlled Trial.
Tormod Skogstad Nilsen, Mali Sæter, Sebastian Imre Sarvari, Kristin Valborg Reinertsen, Sara Hassing Johansen, Adam Philip Sharples

JMIR Res Protoc· November 2023

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Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training.
Brendan Egan, Adam P Sharples

Physiol Rev· July 2023

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Skeletal muscle memory.
Adam P Sharples, Daniel C Turner

Am J Physiol Cell Physiol· June 2023

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Human skeletal muscle methylome after low-carbohydrate energy-balanced exercise.
Piotr P Gorski, Daniel C Turner, Juma Iraki, James P Morton, Adam P Sharples

Am J Physiol Endocrinol Metab· May 2023

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Effects of Aerobic Exercise on Cardiorespiratory Fitness, Cardiovascular Risk Factors, and Patient-Reported Outcomes in Long-Term Breast Cancer Survivors: Protocol for a Randomized Controlled Trial.
Tormod Skogstad Nilsen, Mali Sæter, Sebastian Imre Sarvari, Kristin Valborg Reinertsen, Sara Hassing Johansen, Adam Philip Sharples

JMIR Res Protoc· March 2023

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Different Resistance Exercise Loading Paradigms Similarly Affect Skeletal Muscle Gene Expression Patterns of Myostatin-Related Targets and mTORC1 Signaling Markers.
Mason C McIntosh, Casey L Sexton, Joshua S Godwin, Bradley A Ruple, J Max Michel, Adam P Sharples

Cells· March 2023

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Skeletal Muscle Possesses an Epigenetic Memory of Exercise: Role of Nucleus Type-Specific DNA Methylation.
Adam P Sharples

Function (Oxf)· January 2023

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Aerobic exercise training resets the human skeletal muscle methylome 10 years after breast cancer treatment and survival.
Piotr P Gorski, Truls Raastad, Max Ullrich, Daniel C Turner, Jostein Hallén, Adam P Sharples

FASEB J· January 2023

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Skeletal Muscle DNA Methylation and mRNA Responses to a Bout of Higher versus Lower Load Resistance Exercise in Previously Trained Men.
Casey L Sexton, Joshua S Godwin, Mason C McIntosh, Bradley A Ruple, Shelby C Osburn, Adam P Sharples

Cells· January 2023

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Aging, Skeletal Muscle, and Epigenetics.
Claire E Stewart, Adam P Sharples

Plast Reconstr Surg· October 2022

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Ubiquitin Ligases in Longevity and Aging Skeletal Muscle.
David C Hughes, Leslie M Baehr, David S Waddell, Adam P Sharples, Sue C Bodine

Int J Mol Sci· July 2022

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Mechanical loading of bioengineered skeletal muscle in vitro recapitulates gene expression signatures of resistance exercise in vivo.
Daniel C Turner, Piotr P Gorski, Robert A Seaborne, Mark Viggars, Mark Murphy, Adam P Sharples

J Cell Physiol· September 2021

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Resistance training rejuvenates the mitochondrial methylome in aged human skeletal muscle.
Bradley A Ruple, Joshua S Godwin, Paulo H C Mesquita, Shelby C Osburn, Christopher G Vann, Adam P Sharples

FASEB J· September 2021

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Meta-analysis of genome-wide DNA methylation and integrative omics of age in human skeletal muscle.
Sarah Voisin, Macsue Jacques, Shanie Landen, Nicholas R Harvey, Larisa M Haupt, Adam P Sharples

J Cachexia Sarcopenia Muscle· August 2021

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The Comparative Methylome and Transcriptome After Change of Direction Compared to Straight Line Running Exercise in Human Skeletal Muscle.
Mohd-Firdaus Maasar, Daniel C Turner, Piotr P Gorski, Robert A Seaborne, Juliette A Strauss, Adam P Sharples

Front Physiol· February 2021

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Knockdown of the E3 ubiquitin ligase UBR5 and its role in skeletal muscle anabolism.
David C Hughes, Daniel C Turner, Leslie M Baehr, Robert A Seaborne, Mark Viggars, Adam P Sharples

Am J Physiol Cell Physiol· January 2021

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Graded reductions in pre-exercise glycogen concentration do not augment exercise-induced nuclear AMPK and PGC-1α protein content in human muscle.
Mark A Hearris, Daniel J Owens, Juliette A Strauss, Sam O Shepherd, Adam P Sharples

Exp Physiol· November 2020

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