Publications by authors named "Adrian J Hobbs"

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Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite.
Andrew J Webb, Nakul Patel, Stavros Loukogeorgakis, Mike Okorie, Zainab Aboud, Shivani Misra, Rahim Rashid, Philip Miall, John Deanfield, Nigel Benjamin

Hypertension· March 2008

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Endothelium-derived C-type natriuretic peptide offsets the pathogenesis of pulmonary hypertension.
Joshua P Dignam, Aisah A Aubdool, Vanessa R Lowe, C Perez-Ternero, Amie J Moyes, Adrian J Hobbs

Pharmacol Res· September 2025

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Endothelium- and Fibroblast-Derived C-Type Natriuretic Peptide Prevents the Development and Progression of Aortic Aneurysm.
Aisah A Aubdool, Amie J Moyes, Cristina Perez-Ternero, Reshma S Baliga, Jaspinder Singh Sanghera, Adrian J Hobbs

Arterioscler Thromb Vasc Biol· July 2025

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Endogenous C-type natriuretic peptide offsets the pathogenesis of steatohepatitis, hepatic fibrosis, and portal hypertension.
Cristina Perez-Ternero, Wenhao Li, Aisah A Aubdool, Robert D Goldin, John Loy, Adrian J Hobbs

PNAS Nexus· January 2025

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Cardiomyocyte-derived C-type natriuretic peptide diminishes myocardial ischaemic injury by promoting revascularisation and limiting fibrotic burden.
Vanessa J Lowe, Aisah A Aubdool, Amie J Moyes, Joshua P Dignam, C Perez-Ternero, Adrian J Hobbs

Pharmacol Res· November 2024

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C-type natriuretic peptide (CNP): The cardiovascular system and beyond.
Yasmin A Dickinson, Amie J Moyes, Adrian J Hobbs

Pharmacol Ther· October 2024

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NKX2-5 regulates vessel remodeling in scleroderma-associated pulmonary arterial hypertension.
Ioannis Papaioannou, Athina Dritsoula, Ping Kang, Reshma S Baliga, Sarah L Trinder, Adrian J Hobbs

JCI Insight· April 2024

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Novel enhancers of guanylyl cyclase-A activity acting via allosteric modulation.
Henriette Andresen, Cristina Pérez-Ternero, Jerid Robinson, Deborah M Dickey, Adrian J Hobbs

Br J Pharmacol· December 2023

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The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors.
Stephen P H Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A Mathie, John A Peters, Adrian J Hobbs

Br J Pharmacol· October 2023

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C-type natriuretic peptide preserves central neurological function by maintaining blood-brain barrier integrity.
Cristina Perez-Ternero, Patrick N Pallier, Jordi L Tremoleda, Alessio Delogu, Cathy Fernandes, Adrian J Hobbs

Front Mol Neurosci· October 2022

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The reaction of hydropersulfides (RSSH) with S-nitrosothiols (RS-NO) and the biological/physiological implications.
Jessica Zarenkiewicz, Christina Perez-Ternero, Volga Kojasoy, Christopher McGinity, Vinayak S Khodade, Adrian J Hobbs

Free Radic Biol Med· August 2022

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Cyclic GMP modulating drugs in cardiovascular diseases: mechanism-based network pharmacology.
Alexandra Petraina, Cristian Nogales, Thomas Krahn, Hermann Mucke, Thomas F Lüscher, Adrian J Hobbs

Cardiovasc Res· July 2022

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The role of cGMP signalling in auditory processing in health and disease.
Philine Marchetta, Lukas Rüttiger, Adrian J Hobbs, Wibke Singer, Marlies Knipper

Br J Pharmacol· June 2022

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Multidrug resistance proteins preferentially regulate natriuretic peptide-driven cGMP signalling in the heart and vasculature.
Robert M H Grange, Michael E J Preedy, Aniruthan Renukanthan, Joshua P Dignam, Vanessa J Lowe, Adrian J Hobbs

Br J Pharmacol· June 2022

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A Series of Substituted Bis-Aminotriazines Are Activators of the Natriuretic Peptide Receptor C.
Robert J Smith, Cristina Perez-Ternero, Daniel Conole, Capucine Martin, Samuel H Myers, Adrian J Hobbs

J Med Chem· April 2022

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Animal models of pulmonary hypertension: Getting to the heart of the problem.
Joshua P Dignam, Tara E Scott, Barbara K Kemp-Harper, Adrian J Hobbs

Br J Pharmacol· March 2022

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C-type natriuretic peptide is a pivotal regulator of metabolic homeostasis.
Cristina Perez-Ternero, Aisah A Aubdool, Raj Makwana, Gareth J Sanger, Roland H Stimson, Adrian J Hobbs

Proc Natl Acad Sci U S A· March 2022

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Hydropersulfides (RSSH) and Nitric Oxide (NO) Signaling: Possible Effects on S-Nitrosothiols (RS-NO).
Jon M Fukuto, Cristina Perez-Ternero, Jessica Zarenkiewicz, Joseph Lin, Adrian J Hobbs

Antioxidants (Basel)· January 2022

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Innovative Anti-Inflammatory and Pro-resolving Strategies for Pulmonary Hypertension: High Blood Pressure Research Council of Australia Award 2019.
Tara E Scott, Cheng Xue Qin, Grant R Drummond, Adrian J Hobbs, Barbara K Kemp-Harper

Hypertension· November 2021

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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors.
Stephen Ph Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A Peters, Adrian J Hobbs

Br J Pharmacol· October 2021

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A comparison of the chemical biology of hydropersulfides (RSSH) with other protective biological antioxidants and nucleophiles.
Jon M Fukuto, Adrian J Hobbs

Nitric Oxide· February 2021

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Vascular K channels protect from cardiac dysfunction and preserve cardiac metabolism during endotoxemia.
Qadeer Aziz, Jianmin Chen, Amie J Moyes, Yiwen Li, Naomi A Anderson, Adrian J Hobbs

J Mol Med (Berl)· August 2020

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Combination of cyclic nucleotide modulators with P2Y receptor antagonists as anti-platelet therapy.
Paul C Armstrong, Plinio M Ferreira, Melissa V Chan, Martina H Lundberg Slingsby, Marilena Crescente, Adrian J Hobbs

J Thromb Haemost· July 2020

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Multiplicity of Nitric Oxide and Natriuretic Peptide Signaling in Heart Failure.
Michael E J Preedy, Reshma S Baliga, Adrian J Hobbs

J Cardiovasc Pharmacol· May 2020

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C-type natriuretic peptide co-ordinates cardiac structure and function.
Amie J Moyes, Sandy M Chu, Aisah A Aubdool, Matthew S Dukinfield, Kenneth B Margulies, Adrian J Hobbs

Eur Heart J· March 2020

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C-type Natriuretic Peptide: A Multifaceted Paracrine Regulator in the Heart and Vasculature.
Amie J Moyes, Adrian J Hobbs

Int J Mol Sci· May 2019

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