Publications by authors named "Al Cook"

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An integrated view of the structure and function of the human 4D nucleome.
Job Dekker, Betul Akgol Oksuz, Yang Zhang, Ye Wang, Miriam K Minsk, Ashley L Cook

Nature· December 2025

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Generalizable features of pegRNA design for prime editing of inherited retinal diseases.
Freya M Patterson, Minh Thuan Nguyen Tran, Thomas Guinan, Mohd Khairul Nizam Mohd Khalid, Rajendra Kc, Anthony L Cook

Ophthalmic Genet· November 2025

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Generation of Donor-Specific iPSC for Modelling Lysosomal Storage Disorders.
Sueanne Chear, Adelene Chiam, Jana Talbot, Bryony N Thorne, Emma J Wilkinson, Anthony L Cook

Methods Mol Biol· October 2025

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A 3D iPSC retina model reveals non-cell-autonomous and non-neuronal mechanism of photoreceptor degeneration in a lysosomal storage disorder.
Jimin Han, Nathaniel Foley, Sonal Dalvi, Janet A H Tang, Amit Chatterjee, Anthony L Cook

bioRxiv· July 2025

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Re: Novel Off-Targeting Events Identified after Genome-Wide Analysis of CRISPR-Cas Edited Pigs.
Ashley L Cook, Adam L Moyer, Lynne Boxer, Alexis L Norris

CRISPR J· April 2025

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B cell stimulation changes the structure and higher-order organization of the inactive X chromosome.
Isabel Sierra, Natalie E Toothacre, Robin H van der Weide, Claudia D Lovell, Son C Nguyen, Ashley L Cook

Cell Rep· March 2025

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Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape.
Ashley L Cook, Surojit Sur, Laura Dobbyn, Evangeline Watson, Joshua D Cohen

Elife· February 2025

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B cell stimulation changes the structure and higher-order organization of the inactive X chromosome.
Isabel Sierra, Natalie E Toothacre, Robin H van der Weide, Claudia D Lovell, Son C Nguyen, Ashley L Cook

bioRxiv· February 2025

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Exploring threats to internal validity of direct assessment in single-case design research.
Brian Daniels, Lindsay M Fallon, Andrea Molina Palacios, Margarida B Veiga, Amy L Cook

Sch Psychol· November 2024

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Genetic and Cellular Basis of Impaired Phagocytosis and Photoreceptor Degeneration in CLN3 Disease.
Jimin Han, Sueanne Chear, Jana Talbot, Vicki Swier, Clarissa Booth, Anthony L Cook

Invest Ophthalmol Vis Sci· November 2024

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How is Excitotoxicity Being Modelled in iPSC-Derived Neurons?
Jan L Cheng, Anthony L Cook, Jana Talbot, Sharn Perry

Neurotox Res· October 2024

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An integrated view of the structure and function of the human 4D nucleome.

bioRxiv· October 2024

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HDAC6 inhibition as a mechanism to prevent neurodegeneration in the mSOD1 mouse model of ALS.
Andrew J Phipps, Samuel Dwyer, Jessica M Collins, Fariha Kabir, Rachel Ak Atkinson, Anthony L Cook

Heliyon· July 2024

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Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape.
Ashley L Cook, Surojit Sur, Laura Dobbyn, Evangeline Watson, Joshua D Cohen

bioRxiv· June 2024

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Experimental laboratory models as tools for understanding modifiable dementia risk.
Duncan Sinclair, Alison J Canty, Jenna M Ziebell, Adele Woodhouse, Jessica M Collins, Anthony L Cook

Alzheimers Dement· June 2024

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Genetic and cellular basis of impaired phagocytosis and photoreceptor degeneration in CLN3 disease.
Jimin Han, Sueanne Chear, Jana Talbot, Vicki Swier, Clarissa Booth, Anthony L Cook

bioRxiv· June 2024

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High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma.
Connor J Greatbatch, Qinyi Lu, Sandy Hung, Alexander J Barnett, Kristof Wing, Anthony L Cook

Hum Mol Genet· April 2024

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Polymer Patterning by Laser-Induced Multipoint Initiation of Frontal Polymerization.
Andrés L Cook, Mason A Dearborn, Trevor M Anderberg, Kavya Vaidya, Justin E Jureller

ACS Appl Mater Interfaces· April 2024

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Induced pluripotent stem cell derived pericytes respond to mediators of proliferation and contractility.
Natalie E King, Jo-Maree Courtney, Lachlan S Brown, Alastair J Fortune, Nicholas B Blackburn, Anthony L Cook

Stem Cell Res Ther· March 2024

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Deep Learning-Based Identification of Intraocular Pressure-Associated Genes Influencing Trabecular Meshwork Cell Morphology.
Connor J Greatbatch, Qinyi Lu, Sandy Hung, Son N Tran, Kristof Wing, Anthony L Cook

Ophthalmol Sci· March 2024

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Spatially coordinated heterochromatinization of long synaptic genes in fragile X syndrome.
Thomas Malachowski, Keerthivasan Raanin Chandradoss, Ravi Boya, Linda Zhou, Ashley L Cook

Cell· December 2023

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Seeing Neurodegeneration in a New Light Using Genetically Encoded Fluorescent Biosensors and iPSCs.
David Stellon, Jana Talbot, Alex W Hewitt, Anna E King, Anthony L Cook

Int J Mol Sci· January 2023

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The role of altered protein acetylation in neurodegenerative disease.
Fariha Kabir, Rachel Atkinson, Anthony L Cook, Andrew James Phipps, Anna Elizabeth King

Front Aging Neurosci· January 2023

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Lysosomal alterations and decreased electrophysiological activity in CLN3 disease patient-derived cortical neurons.
Sueanne Chear, Sharn Perry, Richard Wilson, Aidan Bindoff, Jana Talbot, Anthony L Cook

Dis Model Mech· December 2022

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An isogenic cell line panel for sequence-based screening of targeted anticancer drugs.
Ashley L Cook, Nicolas Wyhs, Surojit Sur, Blair Ptak, Maria Popoli

iScience· June 2022

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