Publications by authors named "Alan R Tall"

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Effects of torcetrapib in patients at high risk for coronary events.
Philip J Barter, Mark Caulfield, Mats Eriksson, Scott M Grundy, John J P Kastelein, Michel Komajda, Jose Lopez-Sendon, Lori Mosca, Jean-Claude Tardif, David D Waters

November 2007

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Interleukin-17 receptor-A signalling: atheroprotective role in JAK2 clonal haematopoiesis.
Kun Zhao, Cheng-Chieh Hsu, Yash Pershad, Caitlyn Vlasschaert, Robert W Corty, Alan R Tall

Eur Heart J· December 2025

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Aggressive Cholesterol Lowering Normalizes Atherosclerosis Regression in Mice.
Brian D Hardaway, Trevor P Fidler, Mojdeh Tavallaie, Kleopatra Avrampou, Cheng-Chieh Hsu, Alan R Tall

bioRxiv· November 2025

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Cholesterol Crystals as Triggers of NLRP3 Inflammasome Activation in Atherosclerosis.
Mustafa Yalcinkaya, Alan R Tall

Curr Atheroscler Rep· August 2025

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IL-18 inhibition enlarges lesions, necrotic cores and thickens fibrous caps in clonal hematopoiesis-driven atherosclerosis.
Mojdeh Tavallaie, Cheng-Chieh Hsu, Brian D Hardaway, Huijuan Dou, Trevor Fidler, Alan R Tall

bioRxiv· June 2025

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Comprehensive Multimodal Profiling of Atherosclerosis Reveals Bhlhe40 as a Potential Regulator of Vascular Smooth Muscle Cell Phenotypic Modulation.
Chinyere O Ibikunle, Chenyi Xue, Eunyoung Kim, Hanying Yan, Johana Coronel, Alan R Tall

bioRxiv· May 2025

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Inflammatory crosstalk impairs phagocytic receptors and aggravates atherosclerosis in clonal hematopoiesis in mice.
Wenli Liu, Brian D Hardaway, Eunyoung Kim, Jessica Pauli, Justus Leonard Wettich, Alan R Tall

J Clin Invest· November 2024

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Genetic and epigenetic regulation of inflammasomes: Role in atherosclerosis.
Mustafa Yalcinkaya, Alan R Tall

Atherosclerosis· September 2024

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Hematopoietic and eosinophil-specific LNK(SH2B3) deficiency promotes eosinophilia and arterial thrombosis.
Huijuan Dou, Ranran Wang, Mojdeh Tavallaie, Tong Xiao, Malgorzata Olszewska, Alan R Tall

Blood· April 2024

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Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk.
Wenli Liu, Joachim Pircher, Art Schuermans, Qurrat Ul Ain, Zhe Zhang, Alan R Tall

Blood· April 2024

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Cholesterol trafficking to the ER leads to the activation of CaMKII/JNK/NLRP3 and promotes atherosclerosis.
Mustafa Yalcinkaya, Wenli Liu, Tong Xiao, Sandra Abramowicz, Ranran Wang, Alan R Tall

J Lipid Res· April 2024

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An epigenetic switch in macrophages promotes fibrosis in the failing heart.
Alan R Tall, Trevor P Fidler

Nat Cardiovasc Res· March 2024

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Suppression of IL-1β promotes beneficial accumulation of fibroblast-like cells in atherosclerotic plaques in clonal hematopoiesis.
Trevor P Fidler, Andrew Dunbar, Eunyoung Kim, Brian Hardaway, Jessica Pauli, Alan R Tall

Nat Cardiovasc Res· January 2024

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BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Clonal Hematopoiesis.
Mustafa Yalcinkaya, Wenli Liu, Leigh-Anne Thomas, Malgorzata Olszewska, Tong Xiao, Alan R Tall

Circulation· November 2023

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Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.
Zhi Yu, Trevor P Fidler, Yunfeng Ruan, Caitlyn Vlasschaert, Tetsushi Nakao, Alan R Tall

J Clin Invest· September 2023

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Hematopoietic NLRP3 and AIM2 Inflammasomes Promote Diabetes-Accelerated Atherosclerosis, but Increased Necrosis Is Independent of Pyroptosis.
Cheng-Chieh Hsu, Trevor P Fidler, Jenny E Kanter, Vishal Kothari, Farah Kramer, Alan R Tall

Diabetes· July 2023

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Blockade of IL-6 signaling alleviates atherosclerosis in -deficient clonal hematopoiesis.
Wenli Liu, Mustafa Yalcinkaya, Inés Fernández Maestre, Malgorzata Olszewska, Patrick B Ampomah, Alan R Tall

Nat Cardiovasc Res· June 2023

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Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1β secretion.
Mustafa Yalcinkaya, Panagiotis Fotakis, Wenli Liu, Kaori Endo-Umeda, Huijuan Dou, Alan R Tall

Cardiovasc Res· May 2023

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Inflammasomes and Atherosclerosis: a Mixed Picture.
Alan R Tall, Karin E Bornfeldt

Circ Res· May 2023

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Clonal hematopoiesis and ischemic stroke.
Nan Wang, Alan R Tall

Blood· February 2023

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Cholesterol mass efflux capacity and coronary artery calcium: The Multi-Ethnic Study of Atherosclerosis.
Parveen K Garg, William Tressel, Robyn L McClelland, Michael H Criqui, James H Stein, Alan R Tall

J Clin Lipidol· December 2022

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AIMing 2 treat atherosclerosis.
Oliver Soehnlein, Alan R Tall

Nat Rev Cardiol· September 2022

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Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis.
Wenli Liu, Nataliya Östberg, Mustafa Yalcinkaya, Huijuan Dou, Kaori Endo-Umeda, Alan R Tall

J Clin Invest· July 2022

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Macular Degeneration and CETP Inhibition.
Alan R Tall, Daniel J Rader, John J P Kastelein

JAMA Cardiol· July 2022

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Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis.
Kaori Endo-Umeda, Eunyoung Kim, David G Thomas, Wenli Liu, Huijuan Dou, Alan R Tall

Arterioscler Thromb Vasc Biol· June 2022

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Clonal hematopoiesis in cardiovascular disease and therapeutic implications.
Alan R Tall, Jose J Fuster

Nat Cardiovasc Res· February 2022

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