Publications by authors named "Alessandro Angelini"

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Macrocycle synthesis strategy based on step-wise "adding and reacting" three components enables screening of large combinatorial libraries.
Ganesh K Mothukuri, Sangram S Kale, Carl L Stenbratt, Alessandro Zorzi, Jonathan Vesin, Julien Bortoli Chapalay, Kaycie Deyle, Gerardo Turcatti, Laura Cendron, Alessandro Angelini

June 2020

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Identification of a novel minor-groove DNA binder that represses mitochondrial gene expression and induces apoptosis in highly aggressive leiomyosarcoma cells.
Eleonora Malavasi, Raffaella Picco, Showmeya Mallavarapu, Martina Minisini, Francesca D'Este, Alessandro Angelini

Cell Death Discov· November 2025

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Quantitative Affinity Screening of Macrocyclic Peptide Libraries Using Yeast Surface Display Technology.
Ylenia Mazzocato, Zhanna Romanyuk, Monica Chinellato, Camilla Mazzucco, Linda Trevisan, Alessandro Angelini

Methods Mol Biol· July 2025

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Challenges and Achievements of Peptide Synthesis in Aqueous and Micellar Media.
Francesca Bordignon, Alessandro Scarso, Alessandro Angelini

Chembiochem· June 2025

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Screening macrocyclic peptide libraries by yeast display allows control of selection process and affinity ranking.
Sara Linciano, Ylenia Mazzocato, Zhanna Romanyuk, Filippo Vascon, Lluc Farrera-Soler, Alessandro Angelini

Nat Commun· June 2025

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Albumin-based strategies to effectively prolong the circulation half-life of small immunomodulatory payloads in cancer therapy.
Sara Linciano, Emilia Vigolo, Antonio Rosato, Yoichi Kumada, Alessandro Angelini

Curr Opin Biotechnol· December 2024

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Combination of Coevolutionary Information and Supervised Learning Enables Generation of Cyclic Peptide Inhibitors with Enhanced Potency from a Small Data Set.
Ylenia Mazzocato, Nicola Frasson, Matthew Sample, Cristian Fregonese, Angela Pavan, Alessandro Angelini

ACS Cent Sci· December 2024

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Development of a novel and broadly applicable sandwich ELISA assay based on rabbit single-chain variable fragments and a modified Ig-binding domain of protein L fused to a polystyrene-binding peptide.
Yodai Yamamoto, Haruka Taniguchi, Ngoc Minh Nguyen, Fuki Yokoyama, Kiattawee Choowongkomon, Alessandro Angelini

J Immunol Methods· November 2024

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Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation.
Alexander L Nielsen, Zsolt Bognar, Ganesh K Mothukuri, Anne Zarda, Mischa Schüttel, Alessandro Angelini

Angew Chem Int Ed Engl· June 2024

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Folding of Class IIa HDAC Derived Peptides into α-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
Monica Chinellato, Stefano Perin, Alberto Carli, Luana Lastella, Barbara Biondi, Alessandro Angelini

J Mol Biol· May 2024

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Crystal structure of human serum albumin in complex with megabody reveals unique human and murine cross-reactive binding site.
Sofia De Felice, Zhanna Romanyuk, Monica Chinellato, Giulia Zoia, Sara Linciano, Alessandro Angelini

Protein Sci· February 2024

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In vitro binding analysis of legacy-linear and new generation-cyclic perfluoro-alkyl substances on sex hormone binding globulin and albumin, suggests low impact on serum hormone kinetics of testosterone.
Angela Pavan, Laura Cendron, Andrea Di Nisio, Federica Pedrucci, Iva Sabovic, Alessandro Angelini

Toxicology· December 2023

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A novel genetically-encoded bicyclic peptide inhibitor of human urokinase-type plasminogen activator with better cross-reactivity toward the murine orthologue.
Ylenia Mazzocato, Stefano Perin, Julia Morales-Sanfrutos, Zhanna Romanyuk, Stefano Pluda, Alessandro Angelini

Bioorg Med Chem· November 2023

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Development and characterization of a latex turbidimetric immunoassay using rabbit anti-CRP single-chain Fv antibodies.
Yoichi Kumada, Reina Tanibata, Kimitaka Yamamoto, Hiroshi Noguchi, Alessandro Angelini

J Immunol Methods· September 2023

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Amphiphilic Poly(vinyl alcohol) Membranes Leaving Out Chemical Cross-Linkers: Design, Synthesis, and Function of Tailor-Made Poly(vinyl alcohol)-b-poly(styrene) Copolymers.
Alessandro Angelini, Anja Car, Ionel Adrian Dinu, Luigi Leva, Wilfredo Yave

Macromol Rapid Commun· August 2023

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Antiviral mechanisms of two broad-spectrum monoclonal antibodies for rabies prophylaxis and therapy.
Maira Zorzan, Martina Castellan, Matteo Gasparotto, Guilherme Dias de Melo, Barbara Zecchin, Alessandro Angelini

Front Immunol· August 2023

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Investigation of the Interaction between Human Serum Albumin and Branched Short-Chain Perfluoroalkyl Compounds.
Giulia Moro, Stefano Liberi, Filippo Vascon, Sara Linciano, Sofia De Felice, Alessandro Angelini

Chem Res Toxicol· November 2022

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Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway.
Lorenzo Maso, Filippo Vascon, Monica Chinellato, Frédéric Goormaghtigh, Pierangelo Bellio, Alessandro Angelini

Structure· November 2022

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Bicyclic peptide-based assay for uPA cancer biomarker.
Giulia Moro, Patrick Severin Sfragano, Jessica Ghirardo, Ylenia Mazzocato, Alessandro Angelini

Biosens Bioelectron· October 2022

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Molecular analysis and therapeutic applications of human serum albumin-fatty acid interactions.
Sara Linciano, Giulia Moro, Alessandro Zorzi, Alessandro Angelini

J Control Release· August 2022

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Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale.
Sevan Habeshian, Manuel Leonardo Merz, Gontran Sangouard, Ganesh Kumar Mothukuri, Mischa Schüttel, Alessandro Angelini

Nat Commun· July 2022

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Guidelines, Strategies, and Principles for the Directed Evolution of Cross-Reactive Antibodies Using Yeast Surface Display Technology.
Sara Linciano, Ee Lin Wong, Ylenia Mazzocato, Monica Chinellato, Tiziano Scaravetti, Alessandro Angelini

Methods Mol Biol· May 2022

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Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription.
Martina Minisini, Eros Di Giorgio, Emanuela Kerschbamer, Emiliano Dalla, Massimo Faggiani, Alessandro Angelini

Nucleic Acids Res· March 2022

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Structural Analysis of Human Serum Albumin in Complex with the Fibrate Drug Gemfibrozil.
Stefano Liberi, Sara Linciano, Giulia Moro, Luca De Toni, Laura Cendron, Alessandro Angelini

Int J Mol Sci· February 2022

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Peptide-Based Inhibitors of ADAM and ADAMTS Metalloproteinases.
Stefano Pluda, Ylenia Mazzocato, Alessandro Angelini

Front Mol Biosci· July 2021

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