Publications by authors named "Alex Spyropoulos"

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Influence of Direct Oral Anticoagulant Levels and Thrombin Generation on Postoperative Bleeding [SONAR]: A Nested Case-Control Study.
Joseph R Shaw, Na Li, Matthieu Grussé, Patrick Van Dreden, Melanie St John, Alex C Spyropoulos

Thromb Haemost· December 2025

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Perioperative use of factor concentrates and blood products-a survey of clinical practices in the United States: communication from the ISTH Subcommittee on Perioperative and Critical Care.
Jerrold H Levy, Joseph R Shaw, Kamrouz Ghadimi, Cheryl L Maier, James Douketis, Alex C Spyropoulos

J Thromb Haemost· December 2025

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Direct oral anticoagulant management for neuraxial anaesthesia and deep peripheral nerve blocks.
Aiman Suleiman, William J Sauer, Matthias Eikermann, Christopher Tam, James D Douketis, Alex C Spyropoulos

Br J Anaesth· December 2025

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"Perioperative management of direct oral anticoagulants in patients having a high-bleed-risk surgery or neuraxial procedure: the Perioperative Anticoagulant Use for Surgery Evaluation 2 pilot randomized trial": reply.
James D Douketis, Joseph R Shaw, Alex C Spyropoulos

J Thromb Haemost· December 2025

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Perioperative management of direct oral anticoagulants in patients having a high-bleed-risk surgery or neuraxial procedure: the Perioperative Anticoagulant Use for Surgery Evaluation (PAUSE)-2 pilot randomized trial.
James D Douketis, Na Li, Melanie St John, Joanne Nixon, Karen Moffat, Alex C Spyropoulos

J Thromb Haemost· July 2025

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A Risk Assessment Model for Predicting Perioperative Venous Thromboembolism in Patients Receiving Surgery under Anesthesia Care.
Aline M Grimm, Felix Borngaesser, Fran Ganz-Lord, Annika Bald, Peter Shamamian, Alex C Spyropoulos

Anesthesiology· July 2025

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Venous Thromboembolism Prevention in the Hospitalized Medical Patient.
Nikolaos Tsaftaridis, Anthony Cholagh, Scott Kaatz, Alex C Spyropoulos

Med Clin North Am· July 2025

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Preserving Trial Endpoint Specificity and Cause of Death Attribution in Cardiovascular Trials: Insights From MARINER.
Shea E Hogan, Mario Enrico Canonico, Robert W King, Cecilia C Low Wang, Mark R Nehler, Alex C Spyropoulos

JACC Adv· June 2025

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Perioperative Management of Patients Taking Factor XI Inhibitors: Small Steps Toward a Giant Leap.
James D Douketis, P Gabriel Steg, Suzanne C Cannegieter, Alex C Spyropoulos

J Am Coll Cardiol· June 2025

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Practical guideline for major hereditary thrombophilia.
Liang V Tang, Pierre-Emmanuel Morange, Javier Corral, Georgios Ntaios, Alex C Spyropoulos

Innovation (Camb)· June 2025

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Thromboembolism Risk Profiles in Non-valvular Atrial Fibrillation: How Can Machine Learning-Based Analysis Add to Our Understanding?
Mark Goldin, Alex C Spyropoulos

J Gen Intern Med· May 2025

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Investigating interassay variability between direct oral anticoagulant calibrated anti-factor Xa assays: a substudy of the perioperative anticoagulation use for surgery evaluation (PAUSE) trial.
Ryan M Baker, Rita Selby, Karen A Moffat, Melanie St John, Alex C Spyropoulos

Res Pract Thromb Haemost· May 2025

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Duration of anticoagulation for venous thromboembolism in pediatric patients: Evaluation of the Duration of Therapy for Thrombosis in Children (Kids-DOTT) trial outcomes at 2 years.
Neil A Goldenberg, Sam Schulman, John M Kittelson, Thomas C Abshire, James F Casella, Alex C Spyropoulos

J Thromb Haemost· February 2025

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Standardized Management of Direct Oral Anticoagulants for Elective Procedures.
Alex C Spyropoulos, James D Douketis

JAMA Netw Open· February 2025

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Reversal of Direct Oral Anticoagulants (DOACs) for Critical Bleeding or Urgent Procedures.
Mark Goldin, Nikolaos Tsaftaridis, Jack Jnani, Alex C Spyropoulos

J Clin Med· February 2025

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Anticoagulation Among Patients Hospitalized for COVID-19 : A Systematic Review and Prospective Meta-analysis.

Ann Intern Med· January 2025

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Universal clinical decision support tool for thromboprophylaxis in hospitalized COVID-19 patients: post hoc analysis of the IMPROVE-DD cluster randomized trial.
Mark Goldin, Nikolaos Tsaftaridis, Ioannis Koulas, Jeffrey Solomon, Michael Qiu, Alex C Spyropoulos

J Thromb Haemost· November 2024

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Perioperative Management of Patients Taking Direct Oral Anticoagulants: A Review.
James D Douketis, Alex C Spyropoulos

JAMA· September 2024

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Rivaroxaban Versus Apixaban: A Comparison Without a Simple Solution.
Marc Cohen, Alex C Spyropoulos, Shaun G Goodman, Sarah A Spinler, Marc P Bonaca

Mayo Clin Proc Innov Qual Outcomes· August 2024

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2023 ISTH update of the 2022 ISTH guidelines for antithrombotic treatment in COVID-19.
Sam Schulman, Donald M Arnold, Charlotte A Bradbury, Lisa Broxmeyer, Jean Marie Connors, Alex C Spyropoulos

J Thromb Haemost· June 2024

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Venous thromboembolism risk models in hospitalized medical patients: the time for implementation, not never-ending development.
Alex C Spyropoulos, Eduardo Ramacciotti

Res Pract Thromb Haemost· May 2024

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System-Wide Thromboprophylaxis Interventions for Hospitalized Patients at Risk of Venous Thromboembolism: Focus on Cross-Platform Clinical Decision Support.
Nikolaos Tsaftaridis, Mark Goldin, Alex C Spyropoulos

J Clin Med· April 2024

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Clinical Pathways and Outcomes of Andexanet Alfa Administration for the Reversal of Critical Bleeding in Patients on Oral Direct Factor Xa Inhibitors.
Mark Goldin, Kolton Smith, Ioannis Koulas, Tungming Leung, Mayuri Ravi, Alex C Spyropoulos

TH Open· April 2024

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Prevention and management of venous thromboembolism. International Consensus Statement. Guidelines according to scientific evidence.
Andrew N Nicolaides, Jawed Fareed, Alex C Spyropoulos, Rt Horn Lord Kakkar, Pier L Antignani

Int Angiol· February 2024

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Universal EHRs Clinical Decision Support for Thromboprophylaxis in Medical Inpatients: A Cluster Randomized Trial.
Alex C Spyropoulos, Mark Goldin, Ioannis Koulas, Jeffrey Solomon, Michael Qiu

JACC Adv· October 2023

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