Publications by authors named "Alexandre Cote"

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Revisiting the vulnerable dark triad hypothesis using a bifactor model.
Dominick Gamache, Véronique Maheux-Caron, David Théberge, Alexandre Côté, Marie-Anne Rancourt, Sébastien Hétu, Claudia Savard

October 2023

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Broader Issues in Test Translation and Validation: A Commentary Inspired by Macina et al. (2023).
Dominick Gamache, Philippe Leclerc, Alexandre Côté, David Théberge, Claudia Savard

J Pers Assess· October 2024

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Comprehensive Target Engagement by the EZH2 Inhibitor Tulmimetostat Allows for Targeting of ARID1A Mutant Cancers.
Patricia J Keller, Elizabeth J Adams, Rentian Wu, Alexandre Côté, Shilpi Arora

Cancer Res· August 2024

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Use of research evidence in legislatures: a systematic review.
Mathieu Ouimet, Morgane Beaumier, Adrien Cloutier, Alexandre Côté, Éric Montigny

Evid Policy· January 2023

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GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1.
Alexander M Taylor, Chris Bailey, Lisa D Belmont, Robert Campbell, Nico Cantone

J Med Chem· August 2022

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Social protection and access to assistive technology in low- and middle-income countries.
Alexandre Cote

Assist Technol· December 2021

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Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activity.
Jacob I Stuckey, Nico R Cantone, Alexandre Côté, Shilpi Arora, Valerie Vivat

J Biol Chem· August 2021

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A Proposed Classification of ICD-11 Severity Degrees of Personality Pathology Using the Self and Interpersonal Functioning Scale.
Dominick Gamache, Claudia Savard, Philippe Leclerc, Maude Payant, Nicolas Berthelot

Front Psychiatry· March 2021

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Latent profiles of patients with borderline pathology based on the alternative DSM-5 model for personality disorders.
Dominick Gamache, Claudia Savard, Philippe Leclerc, Maude Payant, Alexandre Côté

Borderline Personal Disord Emot Dysregul· February 2021

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Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time.
Avinash Khanna, Alexandre Côté, Shilpi Arora, Ludivine Moine, Victor S Gehling

ACS Med Chem Lett· June 2020

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Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhibitors.
Victor S Gehling, John P McGrath, Martin Duplessis, Avinash Khanna, Francois Brucelle

ACS Med Chem Lett· June 2020

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Introducing a short self-report for the assessment of DSM-5 level of personality functioning for personality disorders: The Self and Interpersonal Functioning Scale.
Dominick Gamache, Claudia Savard, Philippe Leclerc, Alexandre Côté

Personal Disord· September 2019

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GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like.
Shumei Wang, Vickie Tsui, Terry D Crawford, James E Audia, Daniel J Burdick

J Med Chem· October 2018

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Premature Termination of Psychotherapy in Patients With Borderline Personality Disorder: A Cluster-Analytic Study.
Dominick Gamache, Claudia Savard, Sophie Lemelin, Alexandre Côté, Évens Villeneuve

J Nerv Ment Dis· April 2018

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Premature psychotherapy termination in an outpatient treatment program for personality disorders: a survival analysis.
Dominick Gamache, Claudia Savard, Sophie Lemelin, Alexandre Côté, Evens Villeneuve

Compr Psychiatry· January 2018

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Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance.
Terry D Crawford, Steffan Vartanian, Alexandre Côté, Steve Bellon, Martin Duplessis

Bioorg Med Chem Lett· August 2017

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GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2).
Terry D Crawford, James E Audia, Steve Bellon, Daniel J Burdick, Archana Bommi-Reddy

ACS Med Chem Lett· July 2017

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Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300.
Terry D Crawford, F Anthony Romero, Kwong Wah Lai, Vickie Tsui, Alexander M Taylor

J Med Chem· December 2016

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Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition.
Srimoyee Ghosh, Alexander Taylor, Melissa Chin, Hon-Ren Huang, Andrew R Conery, Alexandre Cote

J Biol Chem· June 2016

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Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains.
Terry D Crawford, Vickie Tsui, E Megan Flynn, Shumei Wang, Alexander M Taylor

J Med Chem· June 2016

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Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637).
Alexander M Taylor, Alexandre Côté, Michael C Hewitt, Richard Pastor, Yves Leblanc

ACS Med Chem Lett· May 2016

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Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomain Inhibitors.
F Anthony Romero, Alexander M Taylor, Terry D Crawford, Vickie Tsui, Alexandre Côté

J Med Chem· February 2016

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Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials.
Brian K Albrecht, Victor S Gehling, Michael C Hewitt, Rishi G Vaswani, Alexandre Côté

J Med Chem· February 2016

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Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains.
Alexander M Taylor, Rishi G Vaswani, Victor S Gehling, Michael C Hewitt, Yves Leblanc

ACS Med Chem Lett· February 2016

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Development of methyl isoxazoleazepines as inhibitors of BET.
Michael C Hewitt, Yves Leblanc, Victor S Gehling, Rishi G Vaswani, Alexandre Côté

Bioorg Med Chem Lett· May 2015

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