Publications by authors named "Alexei N Plotnikov"

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Rivaroxaban in patients with a recent acute coronary syndrome.
Jessica L Mega, Eugene Braunwald, Stephen D Wiviott, Jean-Pierre Bassand, Deepak L Bhatt, Christoph Bode, Paul Burton, Marc Cohen, Nancy Cook-Bruns, Keith A A Fox

January 2012

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Quantitative Model-Informed Dose Selection for a Milvexian Phase III Study in Patients With Atrial Fibrillation.
Wangda Zhou, Emily Bozenhardt, Gregory E Alexander, Matthew L Zierhut, Samira Merali, Alexei N Plotnikov

Clin Pharmacol Ther· January 2026

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Oral factor xia inhibitor milvexian after a recent acute coronary syndrome: Rationale and design of the phase 3 (Librexia ACS).
C Michael Gibson, M Cecilia Bahit, Roxana Mehran, Shamir R Mehta, Rasha Al Lamee, Alexei N Plotnikov

Am Heart J· July 2025

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Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Milvexian in Healthy Chinese Adults.
Zhu Luo, Jie Wang, Zhuolu Niu, Cuili Hu, Madhu Chintala, Alexei N Plotnikov

Drug Des Devel Ther· March 2025

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Milvexian vs apixaban for stroke prevention in atrial fibrillation: The LIBREXIA atrial fibrillation trial rationale and design.
Sneha S Jain, Kenneth W Mahaffey, Karen S Pieper, Wataru Shimizu, Tatjana Potpara, Alexei N Plotnikov

Am Heart J· November 2024

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P2Y12 Inhibitor Switching in Response to Routine Notification of CYP2C19 Clopidogrel Metabolizer Status Following Acute Coronary Syndromes.
Thomas J Povsic, E Magnus Ohman, Matthew T Roe, Jennifer White, Frank W Rockhold, Alexei N Plotnikov

JAMA Cardiol· July 2019

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Usefulness of Rivaroxaban for Secondary Prevention of Acute Coronary Syndrome in Patients With History of Congestive Heart Failure (from the ATLAS-ACS-2 TIMI-51 Trial).
Serge Korjian, Eugene Braunwald, Yazan Daaboul, Michael Mi, Deepak L Bhatt, Alexei N Plotnikov

Am J Cardiol· December 2018

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Rivaroxaban and Post-Stroke Neurological Outcomes in Patients With Acute Coronary Syndrome.
Yazan Daaboul, Serge Korjian, Alexei N Plotnikov, Paul Burton, Eugene Braunwald

J Am Coll Cardiol· March 2018

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The effect of rivaroxaban on myocardial infarction in the ATLAS ACS 2 - TIMI 51 trial.
Matthew A Cavender, C Michael Gibson, Eugene Braunwald, Stephen D Wiviott, Sabina A Murphy, Alexei N Plotnikov

Eur Heart J Acute Cardiovasc Care· October 2015

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Rivaroxaban in patients stabilized after a ST-segment elevation myocardial infarction: results from the ATLAS ACS-2-TIMI-51 trial (Anti-Xa Therapy to Lower Cardiovascular Events in Addition to Standard Therapy in Subjects with Acute Coronary Syndrome-Thrombolysis In Myocardial Infarction-51).
Jessica L Mega, Eugene Braunwald, Sabina A Murphy, Alexei N Plotnikov, Paul Burton

J Am Coll Cardiol· May 2013

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Effect of multiple doses of omeprazole on the pharmacokinetics, pharmacodynamics, and safety of a single dose of rivaroxaban.
Kenneth Todd Moore, Alexei Nikolaevich Plotnikov, An Thyssen, Nicole Vaccaro, Jay Ariyawansa

J Cardiovasc Pharmacol· December 2011

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Pharmacokinetics and pharmacodynamics of rivaroxaban and its effect on biomarkers of hypercoagulability in patients with chronic heart failure.
Mihai Gheorghiade, An Thyssen, Robert Zolynas, Venkatesh K Nadar, Barry H Greenberg, Alexei N Plotnikov

J Heart Lung Transplant· February 2011

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Antithrombotic therapies in patients with heart failure: hypothesis formulation from a research database.
Zhong Yuan, Rachel Weinstein, John Zhang, Mei Cheng, George Griffin, Alexei N Plotnikov

Pharmacoepidemiol Drug Saf· September 2010

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HCN212-channel biological pacemakers manifesting ventricular tachyarrhythmias are responsive to treatment with I(f) blockade.
Alexei N Plotnikov, Annalisa Bucchi, Iryna Shlapakova, Peter Danilo, Peter R Brink

Heart Rhythm· February 2008

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Xenografted adult human mesenchymal stem cells provide a platform for sustained biological pacemaker function in canine heart.
Alexei N Plotnikov, Iryna Shlapakova, Matthias J Szabolcs, Peter Danilo, Beverly H Lorell

Circulation· August 2007

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Long-term cardiac memory in canine heart is associated with the evolution of a transmural repolarization gradient.
Ruben Coronel, Tobias Opthof, Alexei N Plotnikov, Francien J G Wilms-Schopman, Iryna N Shlapakova

Cardiovasc Res· June 2007

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Dispersion of repolarization in canine ventricle and the electrocardiographic T wave: Tp-e interval does not reflect transmural dispersion.
Tobias Opthof, Ruben Coronel, Francien J G Wilms-Schopman, Alexei N Plotnikov, Iryna N Shlapakova

Heart Rhythm· March 2007

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Wild-type and mutant HCN channels in a tandem biological-electronic cardiac pacemaker.
Annalisa Bucchi, Alexei N Plotnikov, Iryna Shlapakova, Peter Danilo, Yelena Kryukova

Circulation· September 2006

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I(Kr) contributes to the altered ventricular repolarization that determines long-term cardiac memory.
Maria N Obreztchikova, Kornelis W Patberg, Alexei N Plotnikov, Nazira Ozgen, Irina N Shlapakova

Cardiovasc Res· July 2006

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Cardiac memory: mechanisms and clinical implications.
Kornelis W Patberg, Alexei Shvilkin, Alexei N Plotnikov, Parag Chandra, Mark E Josephson

Heart Rhythm· December 2005

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The cAMP response element binding protein modulates expression of the transient outward current: implications for cardiac memory.
Kornelis W Patberg, Maria N Obreztchikova, Sarah F Giardina, Aviva J Symes, Alexei N Plotnikov

Cardiovasc Res· November 2005

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Repolarization gradients in the canine left ventricle before and after induction of short-term cardiac memory.
Michiel J Janse, Eugene A Sosunov, Ruben Coronel, Tobias Opthof, Evgeny P Anyukhovsky, Alexei N Plotnikov

Circulation· September 2005

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Atrial gradient as a potential predictor of atrial fibrillation.
Parag Chandra, Tove S Rosen, Bengt Herweg, Alexei N Plotnikov, Peter Danilo

Heart Rhythm· April 2005

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Cardiac memory evolves with age in association with development of the transient outward current.
Alexei N Plotnikov, Eugene A Sosunov, Kornelis W Patberg, Evgeny P Anyukhovsky, Ravil Z Gainullin

Circulation· August 2004

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Biological pacemaker implanted in canine left bundle branch provides ventricular escape rhythms that have physiologically acceptable rates.
Alexei N Plotnikov, Eugene A Sosunov, Jihong Qu, Iryna N Shlapakova, Evgeny P Anyukhovsky

Circulation· February 2004

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