Publications by authors named "Ali Ashkar"

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IL-21-reprogrammed Vδ1 T cells exert killing against solid tumors which is enhanced by CAR arming for off-the-shelf immunotherapy.
Ana L Portillo, Misaal Mehboob, Genesis Snyder, Adnan Moinuddin, Tyrah M Ritchie, Ali A Ashkar

Oncoimmunology· December 2025

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Maternal Diet-Induced Excess Adiposity in Mice Disrupts Mid-Gestation Decidual Immune and Vascular Homeostasis Without Impairing Spiral Artery Remodeling.
Christian J Bellissimo, Erica Yeo, Tatiane A Ribeiro, Patrycja A Jazwiec, Chethana Ellewela, Ali A Ashkar

Acta Physiol (Oxf)· December 2025

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Biological Sex Influences Human Bystander CD8 T Cell Activation.
Elizabeth Balint, Marie Joe Adaimy, Amelia Montemarano, Ana L Portillo, Ali A Ashkar

Eur J Immunol· June 2025

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The impact of oral cannabis consumption during pregnancy on maternal spiral artery remodelling, fetal growth and offspring behaviour in mice.
Tyrah M Ritchie, Emily Feng, Fatemeh Vahedi, Sofya Ermolina, Christian J Bellissimo, Ali A Ashkar

EBioMedicine· April 2025

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CD56 does not contribute to the antitumor, tissue homing, and glycolytic capacity of human NK cells.
Ana L Portillo, Eduardo A Rojas, Misaal Mehboob, Adnan Moinuddin, Elizabeth Balint, Ali A Ashkar

J Leukoc Biol· March 2025

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Metabolic adaptations determine whether natural killer cells fail or thrive within the tumor microenvironment.
Adnan Moinuddin, Sophie M Poznanski, Ana L Portillo, Jonathan K Monteiro, Ali A Ashkar

Immunol Rev· May 2024

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Bystander activated CD8 T cells mediate neuropathology during viral infection via antigen-independent cytotoxicity.
Elizabeth Balint, Emily Feng, Elizabeth C Giles, Tyrah M Ritchie, Alexander S Qian, Ali A Ashkar

Nat Commun· February 2024

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Charting a killer course to the solid tumor: strategies to recruit and activate NK cells in the tumor microenvironment.
Ana L Portillo, Jonathan K Monteiro, Eduardo A Rojas, Tyrah M Ritchie, Amy Gillgrass, Ali A Ashkar

Front Immunol· December 2023

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Natural Killer Cell-Derived Interferon-γ Regulates Macrophage-Mediated Immunopathology During Viral Infection.
Emily Feng, Jonathan K Monteiro, Ana L Portillo, Elizabeth Balint, Ali A Ashkar

J Infect Dis· October 2023

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Targeting the MR1-MAIT cell axis improves vaccine efficacy and affords protection against viral pathogens.
Rasheduzzaman Rashu, Marina Ninkov, Christine M Wardell, Jenna M Benoit, Nicole I Wang, Ali A Ashkar

PLoS Pathog· June 2023

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Type I Interferon Signaling is Required for Oncostatin-M Driven Inflammatory Responses in Mouse Lung.
Kyle MacDonald, Fernando Botelho, Ali A Ashkar, Carl D Richards

J Interferon Cytokine Res· November 2022

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Vaginal transmission causes prolonged Zika virus shedding in the vaginal mucosa and delays systemic dissemination.
Elizabeth Balint, Armaan Amin Somani, Elizabeth C Giles, Emily Feng, Fatemeh Vahedi, Ali A Ashkar

Immunol Cell Biol· July 2022

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Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection.
Amanda J Lee, Emily Feng, Marianne V Chew, Elizabeth Balint, Sophie M Poznanski, Ali A Ashkar

PLoS Pathog· May 2022

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Benralizumab's anti-eosinophil efficacy may be decreased by impaired NK cell activity.
Sophie M Poznanski, Ana Portillo, Manali Mukherjee, Anurag Bhalla, Kiho Son, Ali A Ashkar

Eur Respir J· April 2022

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Correction to "A Pathogen Repellent Plastic Wrap with Built-In Hierarchical Structuring Prevents the Contamination of Surfaces with Coronaviruses".
Roderick MacLachlan, Fatemeh Vahedi, Sara M Imani, Ali A Ashkar, Tohid F Didar

ACS Appl Mater Interfaces· April 2022

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Pathogen-Repellent Plastic Warp with Built-In Hierarchical Structuring Prevents the Contamination of Surfaces with Coronaviruses.
Roderick MacLachlan, Fatemeh Vahedi, Sara M Imani, Ali A Ashkar, Tohid F Didar

ACS Appl Mater Interfaces· March 2022

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Immunoregulatory Functions of Interferons During Genital HSV-2 Infection.
Emily Feng, Elizabeth Balint, Fatemah Vahedi, Ali A Ashkar

Front Immunol· December 2021

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Production of human CAR-NK cells with lentiviral vectors and functional assessment .
Ana L Portillo, Richard Hogg, Ali A Ashkar

STAR Protoc· December 2021

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From Mosquito Bites to Sexual Transmission: Evaluating Mouse Models of Zika Virus Infection.
Elizabeth Balint, Amelia Montemarano, Emily Feng, Ali A Ashkar

Viruses· November 2021

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AHR signaling is induced by infection with coronaviruses.
Federico Giovannoni, Zhaorong Li, Federico Remes-Lenicov, María E Dávola, Mercedes Elizalde, Ali A Ashkar

Nat Commun· August 2021

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Remote hyperinflammation drives neurological disease via T-cell-mediated innate-like cytotoxicity.
Elizabeth Balint, Ali A Ashkar

Cell Mol Immunol· July 2021

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Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells.
Alyssa Vito, Omar Salem, Nader El-Sayes, Ian P MacFawn, Ana L Portillo, Ali A Ashkar

Commun Biol· July 2021

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Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment.
Sophie M Poznanski, Kanwaldeep Singh, Tyrah M Ritchie, Jennifer A Aguiar, Isabella Y Fan, Ali A Ashkar

Cell Metab· June 2021

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Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors.
Ana L Portillo, Richard Hogg, Sophie M Poznanski, Eduardo A Rojas, Niamh J Cashell, Ali A Ashkar

iScience· June 2021

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Aging and Interferons: Impacts on Inflammation and Viral Disease Outcomes.
Emily Feng, Elizabeth Balint, Sophie M Poznanski, Ali A Ashkar, Mark Loeb

Cells· March 2021

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