Publications by authors named "Andrew Kernytsky"

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CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia.
Haydar Frangoul, David Altshuler, M Domenica Cappellini, Yi-Shan Chen, Jennifer Domm, Andrew Kernytsky

N Engl J Med· January 2021

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Evaluation of Homology-Independent CRISPR-Cas9 Off-Target Assessment Methods.
Hemangi G Chaudhari, Jon Penterman, Holly J Whitton, Sarah J Spencer, Nicole Flanagan, Andrew Kernytsky

CRISPR J· December 2020

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A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model.
Fang Wang, Jeremy Travins, Zhizhong Lin, Yaguang Si, Yue Chen, Andrew Kernytsky

J Inherit Metab Dis· November 2016

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MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis.
Katya Marjon, Michael J Cameron, Phong Quang, Michelle F Clasquin, Everton Mandley, Andrew Kernytsky

Cell Rep· April 2016

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IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition.
Andrew Kernytsky, Fang Wang, Erica Hansen, Stefanie Schalm, Kimberly Straley

Blood· January 2015

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An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.
Dan Rohle, Janeta Popovici-Muller, Nicolaos Palaskas, Sevin Turcan, Christian Grommes, Andrew Kernytsky

Science· May 2013

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Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation.
Fang Wang, Jeremy Travins, Byron DeLaBarre, Virginie Penard-Lacronique, Stefanie Schalm, Andrew Kernytsky

Science· May 2013

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A framework for variation discovery and genotyping using next-generation DNA sequencing data.
Mark A DePristo, Eric Banks, Ryan Poplin, Kiran V Garimella, Jared R Maguire, Andrew M Kernytsky

Nat Genet· May 2011

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Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia.
Kiran Musunuru, James P Pirruccello, Ron Do, Gina M Peloso, Candace Guiducci, Andrew Kernytsky

N Engl J Med· December 2010

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The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data.
Aaron McKenna, Matthew Hanna, Eric Banks, Andrey Sivachenko, Kristian Cibulskis, Andrew Kernytsky

Genome Res· September 2010

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Targeted exon sequencing by in-solution hybrid selection.
Brendan Blumenstiel, Kristian Cibulskis, Sheila Fisher, Matthew DeFelice, Andrew Barry, Andrew Kernytsky

Curr Protoc Hum Genet· July 2010

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Using genetic algorithms to select most predictive protein features.
Andrew Kernytsky, Burkhard Rost

Proteins· April 2009

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Membrane protein prediction methods.
Marco Punta, Lucy R Forrest, Henry Bigelow, Andrew Kernytsky, Jinfeng Liu

Methods· April 2007

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Using multiple structure alignments, fast model building, and energetic analysis in fold recognition and homology modeling.
Donald Petrey, Zhexin Xiang, Christopher L Tang, Lei Xie, Marina Gimpelev, Andrew Kernytsky

Proteins· January 2004

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Static benchmarking of membrane helix predictions.
Andrew Kernytsky, Burkhard Rost

Nucleic Acids Res· July 2003

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Transmembrane helix predictions revisited.
Chien Peter Chen, Andrew Kernytsky, Burkhard Rost

Protein Sci· December 2002

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