Publications by authors named "Anne Jansen"

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Checkpoint Blockade Combinations in Tumor Mutational Burden/Load-High Tumors: Insights from the Atezolizumab + Bevacizumab and Nivolumab + Ipilimumab Cohorts in the Drug Rediscovery Protocol.
Karlijn Verkerk, Soemeya F Haj Mohammad, Laurien J Zeverijn, Birgit S Geurts, Ilse A C Spiekman, Anne M L Jansen

Clin Cancer Res· December 2025

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Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol.
Ilse A C Spiekman, Niven Mehra, Laurien J Zeverijn, Birgit S Geurts, Karlijn Verkerk, Anne M L Jansen

Int J Cancer· October 2025

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A Stranger in the Slide: A Rare Collision of a Spitz Melanocytoma With a Novel MYH9::LTK Fusion and a Common BRAF Mutated Nevus Mimicking a Melanoma With a Preexistent Nevus.
Puk R Meijs-Hermanns, Juliette M J Spitzer-Naaijkens, Lennart A Kester, Anne M L Jansen, Willeke A M Blokx

Am J Dermatopathol· August 2025

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Cemento-osseous dysplasia with a NOTCH4 mutation: a case report.
Gerben E Breimer, Nard G Janssen, Anne M L Jansen, Pieter J Slootweg

Virchows Arch· August 2025

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Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics.
Guy Froyen, Pieter-Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Anne M L Jansen

Mol Oncol· June 2025

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Genetic concordance in melanoma: insights from primary tumors and their matched distant metastases.
Thamila Kerkour, Ruud W J Meijers, Loes M Hollestein, Anne M L Jansen, Ayla Haanappel

Melanoma Res· June 2025

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Clinical outcomes and genomic profiles of MAP2K1-mutated primary cutaneous melanocytic tumours.
Chiel F Ebbelaar, Anne M L Jansen, Leonie C M Speet, Frans Schutgens, Sietske Zoetemeyer, Anne-Marie Cleton-Jansen

EBioMedicine· April 2025

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Safety, Efficacy, and Biomarker Analysis of Crizotinib in MET-Mutated Non-Small Cell Lung Cancer-Results from the Drug Rediscovery Protocol.
Karlijn Verkerk, Tijmen J W T van der Wel, Laurien J Zeverijn, Birgit S Geurts, Ilse A C Spiekman, Anne M L Jansen

Clin Cancer Res· December 2024

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The Innate Immune Landscape of dMMR/MSI Cancers Predicts the Outcome of Nivolumab Treatment: Results from the Drug Rediscovery Protocol.
Laurien J Zeverijn, Birgit S Geurts, Thomas W Battaglia, Jade M van Berge Henegouwen, Gijs F de Wit, Anne M L Jansen

Clin Cancer Res· October 2024

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Efficacy of Pembrolizumab and Biomarker Analysis in Patients with WGS-Based Intermediate to High Tumor Mutational Load: Results from the Drug Rediscovery Protocol.
Birgit S Geurts, Laurien J Zeverijn, Lindsay V M Leek, Jade M van Berge Henegouwen, Louisa R Hoes, Anne M L Jansen

Clin Cancer Res· September 2024

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Comparative Performance Analysis of Idylla and Archer in the Detection of Gene Fusions in Spitzoid Melanocytic Tumors.
Chiel F Ebbelaar, Marijke van Dijk, Gerben E Breimer, Ruud W J Meijers, Laura B C Klein, Anne M L Jansen

Mod Pathol· August 2024

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Characterization of discordance between mismatch repair deficiency and microsatellite instability testing may prevent inappropriate treatment with immunotherapy.
Birgit S Geurts, Laurien J Zeverijn, Jade M van Berge Henegouwen, Hanneke van der Wijngaart, Louisa R Hoes, Anne Ml Jansen

J Pathol· July 2024

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Efficacy and Safety of Panitumumab in Patients With RAF/RAS-Wild-Type Glioblastoma: Results From the Drug Rediscovery Protocol.
Ilse A C Spiekman, Birgit S Geurts, Laurien J Zeverijn, Gijs F de Wit, Vincent van der Noort, Anne M L Jansen

Oncologist· May 2024

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Trastuzumab plus pertuzumab for HER2-amplified advanced colorectal cancer: Results from the drug rediscovery protocol (DRUP).
Ilse A C Spiekman, Laurien J Zeverijn, Birgit S Geurts, Karlijn Verkerk, Soemeya F Haj Mohammad, Anne M L Jansen

Eur J Cancer· May 2024

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Limited clinical activity of palbociclib and ribociclib monotherapy in advanced cancers with cyclin D-CDK4/6 pathway alterations in the Dutch DRUP and Australian MoST trials.
Laurien J Zeverijn, Eleonora J Looze, Subotheni Thavaneswaran, J Maxime van Berge Henegouwen, Robert J Simes, Anne M L Jansen

Int J Cancer· October 2023

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Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours.
Birgit S Geurts, Thomas W Battaglia, J Maxime van Berge Henegouwen, Laurien J Zeverijn, Gijs F de Wit, Anne M L Jansen

BMC Cancer· March 2023

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and Mutation Status and Response to Checkpoint Inhibition in Advanced Melanoma.
Olivier J van Not, Willeke A M Blokx, Alfons J M van den Eertwegh, Melissa M de Meza, John B Haanen, Anne M L Jansen

JCO Precis Oncol· September 2022

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Whole Exome Sequencing in Multi-Incident Families Identifies Novel Candidate Genes for Multiple Sclerosis.
Julia Horjus, Tineke van Mourik-Banda, Marco A P Heerings, Marina Hakobjan, Ward De Witte, Anne J Jansen

Int J Mol Sci· September 2022

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Towards diagnostic criteria for malignant deep penetrating melanocytic tumors using single nucleotide polymorphism array and next-generation sequencing.
Chiel F Ebbelaar, Anne M R Schrader, Marijke van Dijk, Ruud W J Meijers, Wendy W J de Leng, Anne M L Jansen

Mod Pathol· August 2022

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Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment.
Louisa R Hoes, Jade M van Berge Henegouwen, Hanneke van der Wijngaart, Laurien J Zeverijn, Daphne L van der Velden, Anne M L Jansen

Clin Cancer Res· April 2022

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FAIR Genomes metadata schema promoting Next Generation Sequencing data reuse in Dutch healthcare and research.
K Joeri van der Velde, Gurnoor Singh, Rajaram Kaliyaperumal, XiaoFeng Liao, Sander de Ridder, Anne M L Jansen

Sci Data· April 2022

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Differences in local immune cell landscape between Q fever and atherosclerotic abdominal aortic aneurysms identified by multiplex immunohistochemistry.
Kimberley R G Cortenbach, Alexander H J Staal, Teske Schoffelen, Mark A J Gorris, Lieke L Van der Woude, Anne F M Jansen

Elife· February 2022

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Patients with Biallelic BRCA1/2 Inactivation Respond to Olaparib Treatment Across Histologic Tumor Types.
Hanneke van der Wijngaart, Louisa R Hoes, J Maxime van Berge Henegouwen, Daphne L van der Velden, Laurien J Zeverijn, Anne M L Jansen

Clin Cancer Res· November 2021

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Genome-wide copy number variations as molecular diagnostic tool for cutaneous intermediate melanocytic lesions: a systematic review and individual patient data meta-analysis.
Chiel F Ebbelaar, Anne M L Jansen, Lourens T Bloem, Willeke A M Blokx

Virchows Arch· October 2021

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Multi-omics examination of Q fever fatigue syndrome identifies similarities with chronic fatigue syndrome.
Ruud P H Raijmakers, Megan E Roerink, Anne F M Jansen, Stephan P Keijmel, Ranko Gacesa

J Transl Med· November 2020

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