Publications by authors named "Benjamin Barwick"

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Enhancing the targeting of the undruggable.
Benjamin G Barwick, Lawrence H Boise

Blood· December 2025

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Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR T cells.
Corynn Kasap, Adila Izgutdina, Bonell Patiño-Escobar, Amrik S Kang, Nikhil Chilakapati, Benjamin G Barwick

Blood· August 2025

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Structure-guided engineering of CCL27 enhances natural ligand CAR T-cells against CCR10 for multiple myeloma.
Nikhil Chilakapati, Bonell Patiño-Escobar, Emily Y Chen, Radhika Dalal, Jonathan de Montagnac, Benjamin G Barwick

bioRxiv· August 2025

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Heme promotes venetoclax resistance in multiple myeloma through MEK-ERK signaling and purine biosynthesis.
Remya Nair, An H Vu, Abigail K Freer, Karanpreet S Bhatia, Dongxue Wang, Benjamin G Barwick

Blood· February 2025

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Predictors of response to venetoclax and therapeutic potential of CDK7 inhibition in multiple myeloma.
Rudra P Dutta, Santiago Thibaud, Violetta Leshchenko, Meghana Ram, David T Melnekoff, Benjamin G Barwick

Blood Neoplasia· December 2024

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KDM6A regulates immune response genes in multiple myeloma.
Daphné Dupéré-Richer, Alberto Riva, Benjamin G Barwick, Sayantan Maji, Heidi Casellas Román

Blood· October 2024

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The epigenetic spectrum of IgM gammopathies.
Benjamin G Barwick

Blood· September 2024

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Functional multiomics reveals genetic and pharmacologic regulation of surface CD38 in multiple myeloma.
Priya Choudhry, Corynn Kasap, Bonell Patiño-Escobar, Olivia Gugliemini, Huimin Geng, Benjamin G Barwick

Blood Neoplasia· September 2024

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NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome.
Amin Sobh, Elena Encinas, Alisha Patel, Greeshma Surapaneni, Emilie Bonilla, Benjamin G Barwick

Blood· July 2024

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Interruption of KLF5 acetylation promotes PTEN-deficient prostate cancer progression by reprogramming cancer-associated fibroblasts.
Baotong Zhang, Mingcheng Liu, Fengyi Mai, Xiawei Li, Wenzhou Wang, Benjamin G Barwick

J Clin Invest· May 2024

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KDM6A Regulates Immune Response Genes in Multiple Myeloma.
Daphne Dupéré-Richer, Alberto Riva, Sayantan Maji, Benjamin G Barwick, Heidi Casellas Román

bioRxiv· February 2024

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Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells.
Corynn Kasap, Adila Izgutdina, Bonell Patiño-Escobar, Amrik Kang, Nikhil Chilakapati, Benjamin G Barwick

bioRxiv· February 2024

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Integrated epigenetic and transcriptional single-cell analysis of t(11;14) multiple myeloma and its BCL2 dependency.
Noémie Leblay, Sungwoo Ahn, Rémi Tilmont, Mansour Poorebrahim, Ranjan Maity, Benjamin G Barwick

Blood· January 2024

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Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma.
Seth J Welsh, Benjamin G Barwick, Erin W Meermeier, Daniel L Riggs, Chang-Xin Shi

Blood Cancer Discov· January 2024

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ETV4-Dependent Transcriptional Plasticity Maintains MYC Expression and Results in IMiD Resistance in Multiple Myeloma.
Paola Neri, Benjamin G Barwick, David Jung, Jonathan C Patton, Ranjan Maity

Blood Cancer Discov· January 2024

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Integrated Genomic Analysis of Primary Prostate Tumor Foci and Corresponding Lymph Node Metastases Identifies Mutations and Pathways Associated with Metastasis.
Carlos S Moreno, Cynthia L Winham, Mehrdad Alemozaffar, Emma R Klein, Ismaheel O Lawal, Benjamin G Barwick

Cancers (Basel)· November 2023

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Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias.
Ricardo de Matos Simoes, Ryosuke Shirasaki, Sondra L Downey-Kopyscinski, Geoffrey M Matthews, Benjamin G Barwick

Nat Cancer· May 2023

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CD8 T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor.
Nataliya Prokhnevska, Maria A Cardenas, Rajesh M Valanparambil, Ewelina Sobierajska, Benjamin G Barwick

Immunity· January 2023

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Inhibition of NADPH Oxidase-ROS Signal using Hyaluronic Acid Nanoparticles for Overcoming Radioresistance in Cancer Therapy.
Lei Zhu, Yi Zhao, Tongrui Liu, Minglong Chen, Wei Ping Qian, Benjamin G Barwick

ACS Nano· November 2022

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β adrenergic signaling regulates hematopoietic stem and progenitor cell commitment and therapy sensitivity in multiple myeloma.
Remya Nair, Vimal Subramaniam, Benjamin G Barwick, Vikas A Gupta, Shannon M Matulis

Haematologica· September 2022

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Therapeutic implications of mitochondrial stress-induced proteasome inhibitor resistance in multiple myeloma.
Aditi Sharma, Remya Nair, Abhinav Achreja, Anjali Mittal, Pulkit Gupta, Benjamin G Barwick

Sci Adv· September 2022

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Venetoclax ex vivo functional profiling predicts improved progression-free survival.
Vikas A Gupta, Shannon M Matulis, Benjamin G Barwick, R Devin Bog, Conrad W Shebelut

Blood Cancer J· August 2022

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PDZ Proteins SCRIB and DLG1 Regulate Myeloma Cell Surface CD86 Expression, Growth, and Survival.
Tyler Moser-Katz, Catherine M Gavile, Benjamin G Barwick, Kelvin P Lee, Lawrence H Boise

Mol Cancer Res· July 2022

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Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients.
Olayinka O Adebayo, Eric B Dammer, Courtney D Dill, Adeyinka O Adebayo, Saheed O Oseni, Benjamin G Barwick

Cancers (Basel)· April 2022

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Aberrant Extrafollicular B Cells, Immune Dysfunction, Myeloid Inflammation, and MyD88-Mutant Progenitors Precede Waldenstrom Macroglobulinemia.
Akhilesh Kaushal, Ajay K Nooka, Allison R Carr, Katherine E Pendleton, Benjamin G Barwick

Blood Cancer Discov· November 2021

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