Publications by authors named "Boon Louis"

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IFNγ-Induced PD-L1+MHCII+ Macrophages and Tim-3+ Tumor-Reactive CD8+ T Cells Predict a Response to Anti-PD-1 Therapy in Tumor-Bearing Mice.
Jelena Gabrilo, Sylvie Vande Velde, Coralie Henin, Sébastien Denanglaire, Abdulkader Azouz, Louis Boon

Cancer Immunol Res· December 2025

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Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti-PD-1 Immunotherapy.
Sana M Arnouk, Daliya Kancheva, Helena Van Damme, Guillaume E Courtoy, Romina Mora Barthelmess, Louis Boon

Cancer Res· December 2025

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Tumor desialylation surpasses anti-PD-L1 checkpoint therapy in restoring anti-tumor immunity in a murine model for colorectal cancer.
Irene van der Haar Àvila, Tao Zhang, Victor Lorrain, Eelco Keuning, Laraib Amir Ali, Louis Boon

Int J Cancer· November 2025

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Allogeneic hematopoietic cell transplantation initiates atherosclerosis in mice via CD8+ T cells.
Ivana Jorgacevic, Haroon Shaikh, Hla Ali, Maja Bundalo, Sarah Schäfer, Louis Boon

Cardiovasc Res· November 2025

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Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis.
Riem Gawish, Rajagopal Varada, Florian Deckert, Anastasiya Hladik, Linda Steinbichl, Louis Boon

J Exp Med· September 2025

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Macrophage IL-4 polarization is restricted by soluble CD40 agonists and antigen-induced CD154 but not by constitutive CD154 expressed by CD4+ T cells.
Mariana Suárez-Martins, Ignacio González-Alayón, Cecilia Casaravilla, Louis Boon, Pedro H Papotto

J Leukoc Biol· July 2025

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The bispecific antibody targeting VISTA and PD-L1 shows enhanced tumor inhibitory activity in pancreatic, endometrial and breast cancers compared to mono- and combination immune checkpoint blockade.
Przemysław Bielski, Jan Barczyński, Michał Mikitiuk, Maja Myrcha, Kamil Rykała, Louis Boon

Front Immunol· May 2025

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Synthetic High-Throughput Microarrays of Peptidoglycan Fragments as a Novel Sero-Diagnostic Tool for Patient Antibody Profiling.
Alexandra Tsouka, Yanyan Fu, Manuel G Ricardo, Peter H Seeberger, Yue Wang, Louis Boon

Angew Chem Int Ed Engl· April 2025

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Modulating IL-21-driven B cell responses in idiopathic inflammatory myopathies via inhibition of the JAK/STAT pathway.
Ana Merino-Vico, Merve Kocyigit, Giulia Frazzei, Lisa Landman, Louis Boon

Arthritis Res Ther· April 2025

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An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence.
Asma Farhat, Mariem Radhouani, Florian Deckert, Sophie Zahalka, Lisabeth Pimenov, Louis Boon

Sci Immunol· March 2025

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Multi-Epitope DC Vaccines with Melanoma Antigens for Immunotherapy of Melanoma.
Athanasios Seretis, Lukas Amon, Christoph H Tripp, Giuseppe Cappellano, Florian Hornsteiner, Louis Boon

Vaccines (Basel)· March 2025

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Peptidoglycan accumulates in distinct brain regions and cell types over lifetime but is absent in newborns.
Carolin Zeiher, Heidrun Kuhrt, Aline Rifflet, Karsten Winter, Louis Boon

Brain Behav Immun· January 2025

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Mgl2 cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation in mice.
Peter C Cook, Sheila L Brown, Emma L Houlder, Julio Furlong-Silva, Daniel P Conn, Louis Boon

Nat Commun· January 2025

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Anti-IL-5 treatment, but not neutrophil interference, attenuates inflammation in a mixed granulocytic asthma mouse model, elicited by air pollution.
Joyceline De Volder, Annelies Bontinck, Valerie Haelterman, Louis Boon, Guy F Joos

Respir Res· January 2025

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Trabectedin promotes oncolytic virus antitumor efficacy, viral gene expression, and immune effector function in models of bone sarcoma.
Emily M Ringwalt, Mark A Currier, Andrea M Glaspell, Chun-Yu Chen, Matthew V Cannon, Louis Boon

Mol Ther Oncol· December 2024

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Interferon gamma-mediated prevention of tumor progression in a mouse model of multiple myeloma.
Zoltán Kellermayer, Sabrin Tahri, Madelon M E de Jong, Natalie Papazian, Cathelijne Fokkema, Louis Boon

Hemasphere· December 2024

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PD-L1 blockade immunotherapy rewires cancer-induced emergency myelopoiesis.
Athina Boumpas, Antonis S Papaioannou, Pavlos Bousounis, Maria Grigoriou, Veronica Bergo, Louis Boon

Front Immunol· October 2024

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Internal regulation between constitutively expressed T cell co-inhibitory receptors BTLA and CD5 and tolerance in recent thymic emigrants.
Adeolu O Adegoke, Govindarajan Thangavelu, Ting-Fang Chou, Marcos I Petersen, Kiyokazu Kakugawa, Louis Boon

Open Biol· October 2024

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A deep intronic splice-altering variant causes APECED syndrome through antisense oligonucleotide-targetable pseudoexon inclusion.
Sebastian Ochoa, Amy P Hsu, Andrew J Oler, Dhaneshwar Kumar, Daniel Chauss, Louis Boon

Sci Transl Med· September 2024

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CD8 T Cells Drive Plaque Smooth Muscle Cell Dedifferentiation in Experimental Atherosclerosis.
Sarah Schäfer, Rajinikanth Gogiraju, Melanie Rösch, Yvonne Kerstan, Lina Beck, Louis Boon

Arterioscler Thromb Vasc Biol· August 2024

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Author Correction: A spatial architecture-embedding HLA signature to predict clinical response to immunotherapy in renal cell carcinoma.
Lisa Kinget, Stefan Naulaerts, Jannes Govaerts, Isaure Vanmeerbeek, Jenny Sprooten, Louis Boon

Nat Med· August 2024

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Targeting conserved TIM3VISTA tumor-associated macrophages overcomes resistance to cancer immunotherapy.
Isaure Vanmeerbeek, Stefan Naulaerts, Jenny Sprooten, Raquel S Laureano, Jannes Govaerts, Louis Boon

Sci Adv· July 2024

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Corrigendum: Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors.
Siddhi N Paudel, Brian J Hutzen, Katherine E Miller, Elizabeth A R Garfinkle, Chun-Yu Chen, Louis Boon

Front Immunol· July 2024

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Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors.
Siddhi N Paudel, Brian J Hutzen, Katherine E Miller, Elizabeth A R Garfinkle, Chun-Yu Chen, Louis Boon

Front Immunol· July 2024

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Immunological synapse formation between T regulatory cells and cancer-associated fibroblasts promotes tumour development.
Athina Varveri, Miranta Papadopoulou, Zacharias Papadovasilakis, Ewoud B Compeer, Aigli-Ioanna Legaki, Louis Boon

Nat Commun· June 2024

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