Publications by authors named "Brian Rodrigues"

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Brief episode of STZ-induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n-6 PUFA.
Sanjoy Ghosh, Dake Qi, Ding An, Thomas Pulinilkunnil, Ashraf Abrahani, Kuo-Hsing Kuo, Richard B Wambolt, Michael Allard, Sheila M Innis, Brian Rodrigues

Am J Physiol Heart Circ Physiol· December 2004

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Cardioprotective effects of a 'twincretin' drug tirzepatide in heart failure following myocardial infarction.
Rui Shang, Brian Rodrigues

Cardiovasc Res· April 2025

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Heparanase Stimulation of Physiologic Cardiac Hypertrophy Is Suppressed After Chronic Diabetes, Resulting in Cardiac Remodeling and Dysfunction.
Chae Syng Lee, Rui Shang, Fulong Wang, Parisa Khayambashi, Hualin Wang, Brian Rodrigues

Diabetes· August 2024

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Downregulation of adipose LPL by PAR2 contributes to the development of hypertriglyceridemia.
Yiheng Huang, Liujun Chen, Lisha Li, Yadan Qi, Haibin Tong, Brian Rodrigues

JCI Insight· July 2024

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Lipoprotein lipase as a target for obesity/diabetes related cardiovascular disease.
Rui Shang, Brian Rodrigues

J Pharm Pharm Sci· July 2024

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Reduction in Insulin Uncovers a Novel Effect of VEGFB on Cardiac Substrate Utilization.
Rui Shang, Chae Syng Lee, Hualin Wang, Roger Dyer, Christophe Noll, Brian Rodrigues

Arterioscler Thromb Vasc Biol· January 2024

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Flow-Induced Secretion of Endothelial Heparanase Regulates Cardiac Lipoprotein Lipase and Changes Following Diabetes.
Chae Syng Lee, Yajie Zhai, Rui Shang, Trevor Wong, Aurora J Mattison, Brian Rodrigues

J Am Heart Assoc· December 2022

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Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia-associated insulin resistance.
Haoning Howard Cen, Bahira Hussein, José Diego Botezelli, Su Wang, Jiashuo Aaron Zhang, Brian Rodrigues

FASEB J· January 2022

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Cardiac-specific VEGFB overexpression reduces lipoprotein lipase activity and improves insulin action in rat heart.
Rui Shang, Nathaniel Lal, Chae Syng Lee, Yajie Zhai, Karanjit Puri, Brian Rodrigues

Am J Physiol Endocrinol Metab· December 2021

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Lipoprotein Lipase and Its Delivery of Fatty Acids to the Heart.
Rui Shang, Brian Rodrigues

Biomolecules· July 2021

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Loss of function of transcription factor EB remodels lipid metabolism and cell death pathways in the cardiomyocyte.
Purvi C Trivedi, Jordan J Bartlett, Angella Mercer, Logan Slade, Marc Surette, Brian Rodrigues

Biochim Biophys Acta Mol Basis Dis· October 2020

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Involvement of Heparanase in Endothelial Cell-Cardiomyocyte Crosstalk.
Rui Shang, Nathaniel Lal, Karanjit Puri, Bahira Hussein, Brian Rodrigues

Adv Exp Med Biol· July 2020

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Diabetes Mellitus Severity and a Switch From Using Lipoprotein Lipase to Adipose-Derived Fatty Acid Results in a Cardiac Metabolic Signature That Embraces Cell Death.
Karanjit Puri, Nathaniel Lal, Rui Shang, Sanjoy Ghosh, Stephane Flibotte, Brian Rodrigues

J Am Heart Assoc· November 2019

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Heparanase protects the heart against chemical or ischemia/reperfusion injury.
Fulong Wang, Thomas Pulinilkunnil, Stephane Flibotte, Corey Nislow, Israel Vlodavsky, Brian Rodrigues

J Mol Cell Cardiol· June 2019

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Vascular Endothelial Growth Factor B and Its Signaling.
Nathaniel Lal, Karanjit Puri, Brian Rodrigues

Front Cardiovasc Med· April 2018

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Reducing insulin via conditional partial gene ablation in adults reverses diet-induced weight gain.
Melissa M Page, Søs Skovsø, Haoning Cen, Amy P Chiu, Derek A Dionne, Brian Rodrigues

FASEB J· March 2018

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Dual effects of hyperglycemia on endothelial cells and cardiomyocytes to enhance coronary LPL activity.
Amy Pei-Ling Chiu, Denise Bierende, Nathaniel Lal, Fulong Wang, Andrea Wan, Brian Rodrigues

Am J Physiol Heart Circ Physiol· January 2018

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Autophagy, Metabolic Disease, and Pathogenesis of Heart Dysfunction.
Fulong Wang, Jocelyn Jia, Brian Rodrigues

Can J Cardiol· July 2017

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Loss of VEGFB and its signaling in the diabetic heart is associated with increased cell death signaling.
Nathaniel Lal, Amy Pei-Ling Chiu, Fulong Wang, Dahai Zhang, Jocelyn Jia, Brian Rodrigues

Am J Physiol Heart Circ Physiol· June 2017

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Heparanase Overexpression Induces Glucagon Resistance and Protects Animals From Chemically Induced Diabetes.
Dahai Zhang, Fulong Wang, Nathaniel Lal, Amy Pei-Ling Chiu, Andrea Wan, Brian Rodrigues

Diabetes· January 2017

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High glucose facilitated endothelial heparanase transfer to the cardiomyocyte modifies its cell death signature.
Fulong Wang, Jocelyn Jia, Nathaniel Lal, Dahai Zhang, Amy Pei-Ling Chiu, Brian Rodrigues

Cardiovasc Res· December 2016

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Cardiomyocyte-endothelial cell control of lipoprotein lipase.
Amy Pei-Ling Chiu, Andrea Wan, Brian Rodrigues

Biochim Biophys Acta· October 2016

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Endothelial cell-cardiomyocyte crosstalk in diabetic cardiomyopathy.
Andrea Wan, Brian Rodrigues

Cardiovasc Res· August 2016

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Lipoprotein lipase and angiopoietin-like 4 - Cardiomyocyte secretory proteins that regulate metabolism during diabetic heart disease.
Prasanth Puthanveetil, Andrea Wan, Brian Rodrigues

Crit Rev Clin Lab Sci· May 2016

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Cardiomyocyte VEGF Regulates Endothelial Cell GPIHBP1 to Relocate Lipoprotein Lipase to the Coronary Lumen During Diabetes Mellitus.
Amy Pei-Ling Chiu, Andrea Wan, Nathaniel Lal, Dahai Zhang, Fulong Wang, Brian Rodrigues

Arterioscler Thromb Vasc Biol· January 2016

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Aggravated restenosis and atherogenesis in ApoCIII transgenic mice but lack of protection in ApoCIII knockouts: the effect of authentic triglyceride-rich lipoproteins with and without ApoCIII.
Haibo Li, Yingchun Han, Rong Qi, Yuhui Wang, Xiaohong Zhang, Brian Rodrigues

Cardiovasc Res· September 2015

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