Publications by authors named "Bruce Bochner"

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The Bruton tyrosine kinase inhibitor acalabrutinib aborts ongoing acute food-induced anaphylactic reactions in humanized mice.
Betania Arce, Natalia M Vilela, Kristin L Chichester, Kristina A Sokol, Santiago Alvarez-Arango, Bruce S Bochner

J Allergy Clin Immunol· November 2025

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Engrafted NSG-SGM3 humanized mice spontaneously produce human immunoglobulins including IgE.
Erica V Lin, Rebecca A Krier-Burris, Kristina A Sokol, Betania Arce, Natalia M Vilela, Bruce S Bochner

Front Immunol· September 2025

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Analysis of human neutrophils from nasal polyps by single-cell RNA sequencing reveals roles of neutrophils in chronic rhinosinusitis.
Naruhito Iwasaki, Julie A Poposki, Masanori Kidoguchi, Aiko Oka, Aiko I Klingler, Bruce S Bochner

J Allergy Clin Immunol· March 2025

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scRNA-seq profiling of human granulocytes reveals expansion of developmentally flexible neutrophil precursors with mixed neutrophil and eosinophil properties in asthma.
Nana-Fatima Haruna, Yuliya Politanska, Andrew R Connelly, Kathrine O'Connor, Sourav Bhattacharya, Bruce S Bochner

J Leukoc Biol· November 2024

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Single cell RNA sequencing of human eosinophils from nasal polyps reveals eosinophil heterogeneity in chronic rhinosinusitis tissue.
Naruhito Iwasaki, Julie A Poposki, Aiko Oka, Masanori Kidoguchi, Aiko I Klingler, Bruce S Bochner

J Allergy Clin Immunol· October 2024

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Biologic therapy in rare eosinophil-associated disorders: remaining questions and translational research opportunities.
Paneez Khoury, Florence Roufosse, Fei Li Kuang, Steven J Ackerman, Praveen Akuthota, Bruce S Bochner

J Leukoc Biol· July 2024

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Prevention of allergic reactions during oxaliplatin desensitization through inhibition of Bruton tyrosine kinase.
Kristin A Erickson, James E Norton, Jennifer Law, Nicole Soriano, Malgorzata Strojny, Bruce S Bochner

J Allergy Clin Immunol· July 2024

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Controlled adsorption of multiple bioactive proteins enables targeted mast cell nanotherapy.
Fanfan Du, Clayton H Rische, Yang Li, Michael P Vincent, Rebecca A Krier-Burris, Bruce S Bochner

Nat Nanotechnol· May 2024

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Little to no mRNA for the α- or β-chains of FcεRI in human eosinophils.
Krishan D Chhiba, Fei Li Kuang, Sergejs Berdnikovs, Atsushi Kato, Bruce S Bochner

J Allergy Clin Immunol· February 2024

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Interactions between Siglec-8 and endogenous sialylated cis ligands restrain cell death induction in human eosinophils and mast cells.
Yun Cao, Clayton H Rische, Bruce S Bochner, Jeremy A O'Sullivan

Front Immunol· November 2023

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Siglecs as potential targets of therapy in human mast cell- and/or eosinophil-associated diseases.
Jeremy A O'Sullivan, Bradford A Youngblood, Robert P Schleimer, Bruce S Bochner

Semin Immunol· September 2023

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A phase II study of Bruton's tyrosine kinase inhibition for the prevention of anaphylaxis.
Ragha V Suresh, Collin Dunnam, Dhananjay Vaidya, Robert A Wood, Bruce S Bochner

J Clin Invest· August 2023

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A Cell-Free Protein Synthesis Platform to Produce a Clinically Relevant Allergen Panel.
Ariel Helms Thames, Clayton H Rische, Yun Cao, Rebecca A Krier-Burris, Fei Li Kuang, Bruce S Bochner

ACS Synth Biol· August 2023

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Siglecs in allergy and asthma.
Bruce S Bochner, Jeremy A O'Sullivan, Alan T Chang, Bradford A Youngblood

Mol Aspects Med· April 2023

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GlycoCAP: A Cell-Free, Bacterial Glycosylation Platform for Building Clickable Azido-Sialoglycoproteins.
Ariel Helms Thames, Sam J Moons, Derek A Wong, Thomas J Boltje, Bruce S Bochner

ACS Synth Biol· April 2023

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Bruton's tyrosine kinase inhibition for the prevention of anaphylaxis: an open-label, phase 2 trial.
Ragha V Suresh, Collin Dunnam, Dhananjay Vaidya, Robert A Wood, Bruce S Bochner

Res Sq· April 2023

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Drug delivery targets and strategies to address mast cell diseases.
Clayton H Rische, Ariel N Thames, Rebecca A Krier-Burris, Jeremy A O'Sullivan, Bruce S Bochner

Expert Opin Drug Deliv· February 2023

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Urine eosinophil-derived neurotoxin: A potential marker of activity in select eosinophilic disorders.
Michelle A Makiya, Paneez Khoury, Fei Li Kuang, Alexis Dominique Mata, Sana Mahmood, Bruce S Bochner

Allergy· January 2023

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Proposed refined diagnostic criteria and classification of eosinophil disorders and related syndromes.
Peter Valent, Amy D Klion, Florence Roufosse, Dagmar Simon, Georgia Metzgeroth, Bruce S Bochner

Allergy· January 2023

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Bioactive multi-protein adsorption enables targeted mast cell nanotherapy.
Fanfan Du, Clayton H Rische, Yang Li, Michael P Vincent, Rebecca A Krier-Burris, Bruce S Bochner

Res Sq· January 2023

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An International, Retrospective Study of Off-Label Biologic Use in the Treatment of Hypereosinophilic Syndromes.
Michael M Chen, Florence Roufosse, Sa A Wang, Srdan Verstovsek, Sandy R Durrani, Bruce S Bochner

J Allergy Clin Immunol Pract· May 2022

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Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells.
Piper A Robida, Clayton H Rische, Netali Ben-Baruch Morgenstern, Rethavathi Janarthanam, Yun Cao, Bruce S Bochner

Cells· March 2022

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Siglec-F Promotes IL-33-Induced Cytokine Release from Bone Marrow-Derived Eosinophils Independently of the ITIM and ITIM-like Motif Phosphorylation.
Stefanie Westermann, Axel Dietschmann, Daniela Doehler, Kirstin Castiglione, Bruce S Bochner

J Immunol· February 2022

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Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death .
Daniela J Carroll, Yun Cao, Bruce S Bochner, Jeremy A O'Sullivan

Front Immunol· December 2021

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COVID-19 vaccine-related presumed allergic reactions and second dose administration by using a two-step graded protocol.
Gayatri B Patel, Krishan D Chhiba, Michael M Chen, Amina Guo, Melissa M Watts, Bruce S Bochner

Allergy Asthma Proc· November 2021

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