Publications by authors named "Christie Orschell"

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16,16 dimethyl-prostaglandin E2 Administration Prior to Lethal Irradiation Ameliorates Long-term Immune Suppression.
Tong Wu, P Artur Plett, Carol H Sampson, Hui Lin Chua, Alexa Fisher, Christie M Orschell

Radiat Res· November 2025

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Dose Optimization and Receptor Utilization of Prostaglandin E Analogs for Radioprotection and Radiomitigation of H-ARS and DEARE.
Tong Wu, P Artur Plett, Hailin Feng, Carol H Sampson, Louis M Pelus, Christie M Orschell

Radiat Res· October 2025

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The Radioprotective Effects of 16, 16 dimethyl Prostaglandin E2 on Survival and Hematopoiesis are Mediated Through Co-Stimulation of the EP3 and EP4 Receptors.
Seiji Fukuda, Andrea M Patterson, Tong Wu, Pratibha Singh, P Artur Plett, Christie M Orschell

Radiat Res· June 2025

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IEPA, a novel radiation countermeasure, alleviates acute radiation syndrome in rodents.
Radoslaw Wesolowski, Brian L Fish, Michael Eibl, Stella Bähr, Srishti Munjal Mehta, Christie M Orschell

Int J Radiat Biol· January 2025

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Effect of Age at Time of Irradiation, Sex, Genetic Diversity, and Granulopoietic Cytokine Radiomitigation on Lifespan and Lymphoma Development in Murine H-ARS Survivors.
P Artur Plett, Hui Lin Chua, Tong Wu, Carol H Sampson, Theresa A Guise, Christie M Orschell

Radiat Res· September 2024

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Pharmacokinetics and Biodistribution of 16,16 dimethyl Prostaglandin E2 in Non-Irradiated and Irradiated Mice and Non-Irradiated Non-Human Primates.
Brooke Langevin, Pratibha Singh, P Artur Plett, Carol H Sampson, Andi Masters, Christie M Orschell

Radiat Res· January 2024

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The delayed effects of acute radiation exposure (DEARE): characteristics, mechanisms, animal models, and promising medical countermeasures.
Tong Wu, Christie M Orschell

Int J Radiat Biol· June 2023

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Further Characterization of Multi-Organ DEARE and Protection by 16,16 Dimethyl Prostaglandin E2 in a Mouse Model of the Hematopoietic Acute Radiation Syndrome.
Tong Wu, Louis M Pelus, P Artur Plett, Carol H Sampson, Hui Lin Chua, Christie M Orschell

Radiat Res· May 2023

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Medical countermeasures for the hematopoietic-subsyndrome of acute radiation syndrome in space.
Dawn N Kernagis, Elizabeth Balcer-Kubiczek, Soha Bazyar, Christie M Orschell, Isabel L Jackson

Life Sci Space Res (Amst)· November 2022

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Hematopoietic Stem Cell Identification Postirradiation.
Andrea M Patterson, Christie M Orschell, Louis M Pelus

Methods Mol Biol· October 2022

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Establishing a Murine Model of the Hematopoietic Acute Radiation Syndrome.
P Artur Plett, Louis M Pelus, Christie M Orschell

Methods Mol Biol· October 2022

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Age and Sex Divergence in Hematopoietic Radiosensitivity in Aged Mouse Models of the Hematopoietic Acute Radiation Syndrome.
Andrea M Patterson, Sasidhar Vemula, P Artur Plett, Carol H Sampson, Hui Lin Chua, Christie M Orschell

Radiat Res· September 2022

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Impact of Age, Sex, and Genetic Diversity in Murine Models of the Hematopoietic Acute Radiation Syndrome (H-ARS) and the Delayed Effects of Acute Radiation Exposure (DEARE).
Christie M Orschell, Tong Wu, Andrea M Patterson

Curr Stem Cell Rep· September 2022

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Upregulation of SIRT1 Contributes to dmPGE2-dependent Radioprotection of Hematopoietic Stem Cells.
Liqiong Liu, Hongge Li, Andrea M Patterson, P Artur Plett, Carol H Sampson, Christie M Orschell

Stem Cell Rev Rep· April 2022

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Prostaglandin E Enhances Aged Hematopoietic Stem Cell Function.
Andrea M Patterson, P Artur Plett, Carol H Sampson, Edward Simpson, Yunlong Liu, Christie M Orschell

Stem Cell Rev Rep· October 2021

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Corrigendum: Polypharmacy to Mitigate Acute and Delayed Radiation Syndromes.
Tracy Gasperetti, Tessa Miller, Feng Gao, Jayashree Narayanan, Elizabeth R Jacobs, Christie M Orschell

Front Pharmacol· August 2021

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Polypharmacy to Mitigate Acute and Delayed Radiation Syndromes.
Tracy Gasperetti, Tessa Miller, Feng Gao, Jayashree Narayanan, Elizabeth R Jacobs, Christie M Orschell

Front Pharmacol· May 2021

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Establishing Pediatric Mouse Models of the Hematopoietic Acute Radiation Syndrome and the Delayed Effects of Acute Radiation Exposure.
Andrea M Patterson, Rajendran Sellamuthu, P Artur Plett, Carol H Sampson, Hui Lin Chua, Christie M Orschell

Radiat Res· April 2021

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Optimizing and Profiling Prostaglandin E2 as a Medical Countermeasure for the Hematopoietic Acute Radiation Syndrome.
Andrea M Patterson, Tong Wu, Hui Lin Chua, Carol H Sampson, Alexa Fisher, Christie M Orschell

Radiat Res· February 2021

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Mitigating oxygen stress enhances aged mouse hematopoietic stem cell numbers and function.
Maegan L Capitano, Safa F Mohamad, Scott Cooper, Bin Guo, Xinxin Huang, Christie M Orschell

J Clin Invest· January 2021

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Fate of Hematopoiesis During Aging. What Do We Really Know, and What are its Implications?
Hal E Broxmeyer, Yan Liu, Reuben Kapur, Christie M Orschell, Arafat Aljoufi

Stem Cell Rev Rep· December 2020

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A Potential Role for Excess Tissue Iron in Development of Cardiovascular Delayed Effects of Acute Radiation Exposure.
Steven J Miller, Supriya Chittajallu, Carol Sampson, Alexa Fisher, Joseph L Unthank, Christie M Orschell

Health Phys· November 2020

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Development of a Model of the Acute and Delayed Effects of High Dose Radiation Exposure in Jackson Diversity Outbred Mice; Comparison to Inbred C57BL/6 Mice.
Andrea M Patterson, P Artur Plett, Hui Lin Chua, Carol H Sampson, Alexa Fisher, Christie M Orschell

Health Phys· November 2020

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Immune Reconstitution and Thymic Involution in the Acute and Delayed Hematopoietic Radiation Syndromes.
Tong Wu, P Artur Plett, Hui Lin Chua, Max Jacobsen, George E Sandusky, Christie M Orschell

Health Phys· November 2020

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The Access Technology Program of the Indiana Clinical Translational Sciences Institute (CTSI): A model to facilitate access to cutting-edge technologies across a state.
Christie M Orschell, Todd C Skaar, Melanie E DeFord, Joel Ybe, Julie Driscol

J Clin Transl Sci· August 2020

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