Publications by authors named "Christoph Spahn"

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Democratising deep learning for microscopy with ZeroCostDL4Mic.
Lucas von Chamier, Romain F Laine, Johanna Jukkala, Christoph Spahn, Daniel Krentzel, Elias Nehme, Martina Lerche, Sara Hernández-Pérez, Pieta K Mattila, Eleni Karinou

Nat Commun· April 2021

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Activation of the Yersinia type III secretion system induces large-scale spatial reorganization of chromosomal and virulence plasmid DNA.
Francesca Ermoli, Christoph Spahn, Ismath Sadhir, Helge B Bode, Andreas Diepold

Cell Rep· November 2025

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Yersinia actively downregulates type III secretion and adhesion at higher cell densities.
Francesca Ermoli, Gabriele Malengo, Christoph Spahn, Corentin Brianceau, Timo Glatter

PLoS Pathog· August 2025

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The nucleoid of rapidly growing Escherichia coli localizes close to the inner membrane and is organized by transcription, translation, and cell geometry.
Christoph Spahn, Stuart Middlemiss, Estibaliz Gómez-de-Mariscal, Ricardo Henriques, Helge B Bode

Nat Commun· April 2025

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Cell-free biosynthesis combined with deep learning accelerates de novo-development of antimicrobial peptides.
Amir Pandi, David Adam, Amir Zare, Van Tuan Trinh, Stefan L Schaefer, Christoph Spahn

Nat Commun· November 2023

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Nanoscale organization of the MHC I peptide-loading complex in human dendritic cells.
Nicole Koller, Philipp Höllthaler, Martina Barends, Marius Döring, Christoph Spahn

Cell Mol Life Sci· August 2022

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DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches.
Christoph Spahn, Estibaliz Gómez-de-Mariscal, Romain F Laine, Pedro M Pereira, Lucas von Chamier

Commun Biol· July 2022

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Multi-Color, Bleaching-Resistant Super-Resolution Optical Fluctuation Imaging with Oligonucleotide-Based Exchangeable Fluorophores.
Marius Glogger, Christoph Spahn, Jörg Enderlein, Mike Heilemann

Angew Chem Int Ed Engl· March 2021

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Microbial Cationic Peptides as a Natural Defense Mechanism against Insect Antimicrobial Peptides.
Tien Duy Vo, Christoph Spahn, Mike Heilemann, Helge B Bode

ACS Chem Biol· March 2021

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Protein-Specific, Multicolor and 3D STED Imaging in Cells with DNA-Labeled Antibodies.
Christoph Spahn, Florian Hurter, Mathilda Glaesmann, Christos Karathanasis, Marko Lampe

Angew Chem Int Ed Engl· December 2019

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Whole-Cell, 3D, and Multicolor STED Imaging with Exchangeable Fluorophores.
Christoph Spahn, Jonathan B Grimm, Luke D Lavis, Marko Lampe, Mike Heilemann

Nano Lett· January 2019

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A toolbox for multiplexed super-resolution imaging of the E. coli nucleoid and membrane using novel PAINT labels.
Christoph K Spahn, Mathilda Glaesmann, Jonathan B Grimm, Anthony X Ayala, Luke D Lavis

Sci Rep· October 2018

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The Pearling Transition Provides Evidence of Force-Driven Endosomal Tubulation during Infection.
Yunfeng Gao, Christoph Spahn, Mike Heilemann, Linda J Kenney

mBio· June 2018

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Sequential Super-Resolution Imaging of Bacterial Regulatory Proteins: The Nucleoid and the Cell Membrane in Single, Fixed E. coli Cells.
Christoph Spahn, Mathilda Glaesmann, Yunfeng Gao, Yong Hwee Foo, Marko Lampe

Methods Mol Biol· April 2018

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Erratum to: Sequential Super-Resolution Imaging of Bacterial Regulatory Proteins, the Nucleoid and the Cell Membrane in Single, Fixed E. coli Cells.
Christoph Spahn, Mathilda Glaesmann, Yunfeng Gao, Yong Hwee Foo, Marko Lampe

Methods Mol Biol· January 2017

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Nanoscopy of bacterial cells immobilized by holographic optical tweezers.
Robin Diekmann, Deanna L Wolfson, Christoph Spahn, Mike Heilemann, Mark Schüttpelz

Nat Commun· December 2016

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Temporal accumulation analysis provides simplified artifact-free analysis of membrane-protein nanoclusters.
Christoph Spahn, Frank Herrmannsdörfer, Thomas Kuner, Mike Heilemann

Nat Methods· November 2016

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BACE-1 is expressed in the blood-brain barrier endothelium and is upregulated in a murine model of Alzheimer's disease.
Kavi Devraj, Slobodan Poznanovic, Christoph Spahn, Gerhard Schwall, Patrick N Harter

J Cereb Blood Flow Metab· July 2016

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Single cell super-resolution imaging of E. coli OmpR during environmental stress.
Yong Hwee Foo, Christoph Spahn, Hongfang Zhang, Mike Heilemann, Linda J Kenney

Integr Biol (Camb)· October 2015

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Correlative super-resolution imaging of RNA polymerase distribution and dynamics, bacterial membrane and chromosomal structure in Escherichia coli.
Christoph Spahn, Francesca Cella-Zannacchi, Ulrike Endesfelder, Mike Heilemann

Methods Appl Fluoresc· March 2015

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Click chemistry facilitates direct labelling and super-resolution imaging of nucleic acids and proteins†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4ra01027bClick here for additional data file.
Anika Raulf, Christoph K Spahn, Patrick J M Zessin, Kieran Finan, Stefan Bernhardt

RSC Adv· July 2014

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Increasing the brightness of cyanine fluorophores for single-molecule and superresolution imaging.
Kathrin Klehs, Christoph Spahn, Ulrike Endesfelder, Steven F Lee, Alexandre Fürstenberg

Chemphyschem· March 2014

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Super-resolution imaging of Escherichia coli nucleoids reveals highly structured and asymmetric segregation during fast growth.
Christoph Spahn, Ulrike Endesfelder, Mike Heilemann

J Struct Biol· March 2014

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Dielectric analysis and multi-cell electrofusion of the yeast Pichia pastoris for electrophysiological studies.
Ulrich Terpitz, Sebastian Letschert, Ulrich Bonda, Christoph Spahn, Chonglin Guan

J Membr Biol· December 2012

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