Publications by authors named "Christopher Scanlan"

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Redirecting adenoviruses to tumour cells using therapeutic antibodies: Generation of a versatile human bispecific adaptor.
Snezana Vasiljevic, Emma V Beale, Camille Bonomelli, Iona S Easthope, Laura K Pritchard, Christopher N Scanlan

Mol Immunol· December 2015

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Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies.
Laura K Pritchard, Daniel I R Spencer, Louise Royle, Camille Bonomelli, Gemma E Seabright, Christopher N Scanlan

Nat Commun· June 2015

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Fragments of bacterial endoglycosidase s and immunoglobulin g reveal subdomains of each that contribute to deglycosylation.
Emma V Dixon, Jolyon K Claridge, David J Harvey, Kavitha Baruah, Xiaojie Yu, Christopher N Scanlan

J Biol Chem· May 2014

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Emerging principles for the therapeutic exploitation of glycosylation.
Martin Dalziel, Max Crispin, Christopher N Scanlan, Nicole Zitzmann, Raymond A Dwek

Science· January 2014

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Travelling wave ion mobility and negative ion fragmentation for the structural determination of N-linked glycans.
David J Harvey, Charlotte A Scarff, Matthew Edgeworth, Max Crispin, Christopher N Scanlan

Electrophoresis· August 2013

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Engineering hydrophobic protein-carbohydrate interactions to fine-tune monoclonal antibodies.
Xiaojie Yu, Kavitha Baruah, David J Harvey, Snezana Vasiljevic, Dominic S Alonzi, Christopher N Scanlan

J Am Chem Soc· July 2013

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Dissecting the molecular mechanism of IVIg therapy: the interaction between serum IgG and DC-SIGN is independent of antibody glycoform or Fc domain.
Xiaojie Yu, Snezana Vasiljevic, Daniel A Mitchell, Max Crispin, Christopher N Scanlan

J Mol Biol· April 2013

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MALDI-MS/MS with traveling wave ion mobility for the structural analysis of N-linked glycans.
David J Harvey, Charlotte A Scarff, Max Crispin, Christopher N Scanlan, Camille Bonomelli

J Am Soc Mass Spectrom· November 2012

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Chemical and structural analysis of an antibody folding intermediate trapped during glycan biosynthesis.
Thomas A Bowden, Kavitha Baruah, Charlotte H Coles, David J Harvey, Xiaojie Yu, Christopher N Scanlan

J Am Chem Soc· October 2012

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Selective deactivation of serum IgG: a general strategy for the enhancement of monoclonal antibody receptor interactions.
Kavitha Baruah, Thomas A Bowden, Benjamin A Krishna, Raymond A Dwek, Max Crispin, Christopher N Scanlan

J Mol Biol· June 2012

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An endoglycosidase with alternative glycan specificity allows broadened glycoprotein remodelling.
Jonathan J Goodfellow, Kavitha Baruah, Keisuke Yamamoto, Camille Bonomelli, Benjamin Krishna, Christopher N Scanlan

J Am Chem Soc· May 2012

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The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.
Camille Bonomelli, Katie J Doores, D Cameron Dunlop, Victoria Thaney, Raymond A Dwek, Christopher N Scanlan

PLoS One· February 2012

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A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Robert Pejchal, Katie J Doores, Laura M Walker, Reza Khayat, Po-Ssu Huang, Christopher N Scanlan

Science· November 2011

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Use of the α-mannosidase I inhibitor kifunensine allows the crystallization of apo CTLA-4 homodimer produced in long-term cultures of Chinese hamster ovary cells.
Chao Yu, Max Crispin, Andreas F-P Sonnen, David J Harvey, Veronica T Chang, Christopher N Scanlan

Acta Crystallogr Sect F Struct Biol Cryst Commun· July 2011

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Ion mobility mass spectrometry for extracting spectra of N-glycans directly from incubation mixtures following glycan release: application to glycans from engineered glycoforms of intact, folded HIV gp120.
David J Harvey, Frank Sobott, Max Crispin, Antoni Wrobel, Camille Bonomelli, Christopher N Scanlan

J Am Soc Mass Spectrom· March 2011

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Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity.
Leopold Kong, Neil C Sheppard, Guillaume B E Stewart-Jones, Cynthia L Robson, Hongying Chen, Christopher N Scanlan

J Mol Biol· October 2010

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A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.
Katie J Doores, Zara Fulton, Vu Hong, Mitul K Patel, Christopher N Scanlan

Proc Natl Acad Sci U S A· October 2010

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Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.
Katie J Doores, Camille Bonomelli, David J Harvey, Snezana Vasiljevic, Raymond A Dwek, Christopher N Scanlan

Proc Natl Acad Sci U S A· August 2010

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Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans.
D Cameron Dunlop, Camille Bonomelli, Fatma Mansab, Snezana Vasiljevic, Katie J Doores, Christopher N Scanlan

Glycobiology· July 2010

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Application of negative ion MS/MS to the identification of N-glycans released from carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1).
David J Harvey, Kavitha Baruah, Christopher N Scanlan

J Mass Spectrom· January 2009

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Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
D Cameron Dunlop, Alexander Ulrich, Ben J Appelmelk, Dennis R Burton, Raymond A Dwek, Christopher N Scanlan

AIDS· October 2008

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A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.
Rena D Astronomo, Hing-Ken Lee, Christopher N Scanlan, Ralph Pantophlet, Cheng-Yuan Huang

J Virol· July 2008

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Making autoantibodies safe.
Christopher N Scanlan, Dennis R Burton, Raymond A Dwek

Proc Natl Acad Sci U S A· March 2008

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Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody.
Christopher N Scanlan, Gayle E Ritchie, Kavitha Baruah, Max Crispin, David J Harvey

J Mol Biol· September 2007

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Exploiting the defensive sugars of HIV-1 for drug and vaccine design.
Christopher N Scanlan, John Offer, Nicole Zitzmann, Raymond A Dwek

Nature· April 2007

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