Publications by authors named "Clark Chen"

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The Comparative Performance of Large Language Models on the Hand Surgery Self-Assessment Examination.
Clark J Chen, Keenan Sobol, Connor Hickey, James Raphael

Hand (N Y)· January 2026

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A novel intraoperative classification for brachial plexus birth injury based on operative findings in 162 patients.
Dan A Zlotolow, Clark J Chen, Christopher S Crowe, Eugene Park, Scott H Kozin

J Hand Surg Eur Vol· December 2025

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Redefining the therapeutic landscape of glioblastomas and brain metastasis through cesium brachytherapy and low-kV intra-operative radiation therapy (IORT).
Carlin Chuck, Abigail Teshome, Alice Lin, Sumaiya Sayeed, Elaina Wang, Hsien-Chung Chen, Clark C Chen

J Neurooncol· November 2025

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Feedforward miR-181d degradation modulates population variance of methyl-guanine methyl transferase and temozolomide resistance.
Gatikrushna Singh, Shilpi Singh, Iteeshree Mohapatra, Stefan Kim, Mayur Sharma, Clark C Chen

Cell Rep· November 2025

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Droplet Hi-C enables scalable, single-cell profiling of chromatin architecture in heterogeneous tissues.
Lei Chang, Yang Xie, Brett Taylor, Zhaoning Wang, Jiachen Sun, Clark C Chen

Nat Biotechnol· October 2025

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Author Correction: Droplet Hi-C enables scalable, single-cell profiling of chromatin architecture in heterogeneous tissues.
Lei Chang, Yang Xie, Brett Taylor, Zhaoning Wang, Jiachen Sun, Clark C Chen

Nat Biotechnol· October 2025

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Harnessing ferroptosis to transform glioblastoma therapy and surmount treatment resistance.
Shilpi Singh, Iteeshree Mohapatra, Debashis Barik, Haoyi Zheng, Stefan Kim, Clark C Chen

Cell Death Discov· October 2025

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Trends in glioblastoma treatment, survival, and disparities in access to care in the United States from 2004 to 2019: a National Cancer Database analysis.
John Pham, Jonathan Sisti, David J Cote, Keiko Kang, Robert G Briggs, Clark C Chen

J Neurosurg· September 2025

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Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial.
Farshad Nassiri, Vikas Patil, Leeor S Yefet, Olivia Singh, Jeff Liu, Clark C Chen

Nat Med· September 2025

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FLAIR extending beyond a quadrant (FEQ) of the cerebrum as a qualitative imaging biomarker: a conceptual proposition and proof-of-principle.
Ali A Alattar, Jiri Bartek, Carlin Chuck, Giovanni Kozel, Elaina J Wang, Hsien-Chung Chen, Clark C Chen

Clin Exp Metastasis· September 2025

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Enabling CAR-T Cell Immunotherapy in Glioblastoma by Modifying Tumor Microenvironment via Oncolytic Adenovirus Encoding Bispecific T Cell Engager.
Moon Jung Choi, Eui Young So, Bedia Akosman, Young Eun Lee, Alexander G Raufi, Clark C Chen

bioRxiv· August 2025

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Acquired resistance to molecularly targeted therapies for cancer.
Nolan M Stubbs, Tyler J Roady, Maximilian P Schwermann, Elias O Eteshola, William J MacDonald, Liang Cheng, Clark C Chen

Cancer Drug Resist· June 2025

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Robot-assisted trigeminal nerve rhizotomy with radiofrequency ablation using Globus ExcelsiusGPS: illustrative case.
Joseph Rajasekaran, Rajan Thakore, Rohaid Ali, Hael Abdulrazeq, Carlin Chuck, Clark C Chen

J Neurosurg Case Lessons· June 2025

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Treatment practices and survival outcomes for IDH-wildtype glioblastoma patients according to MGMT promoter methylation status: insights from the U.S. National Cancer Database.
John Pham, David J Cote, Keiko Kang, Robert G Briggs, David Gomez, Clark C Chen

J Neurooncol· May 2025

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Imipridones ONC201/ONC206 + RT/TMZ triple (IRT) therapy reduces intracranial tumor burden, prolongs survival in orthotopic IDH-WT GBM mouse model, and suppresses MGMT.
Lanlan Zhou, Leiqing Zhang, Jun Zhang, Laura Jinxuan Wu, Shengliang Zhang, Clark C Chen

Oncotarget· March 2025

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IGV-001 cellular immunotherapy for newly diagnosed glioblastoma: overcoming the logistic challenge.
Eric T Wong, Deus Cielo, Konstantina Svokos, Curt Doberstein, Prakash Sampath, Clark C Chen

Front Oncol· March 2025

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Reduced EZH1/2 expression in imipridone-treated cells correlates with synergy following combinations with EZH1/2 or HDAC inhibitors in diffuse glioma and other tumors.
Yiqun Zhang, Kelsey E Huntington, Attila A Seyhan, Nikos Tapinos, Rishi R Lulla, Clark C Chen

Am J Cancer Res· March 2025

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Vasopressor Use in Acute Spinal Cord Injury: Current Evidence and Clinical Implications.
Mazen Taman, Hael Abdulrazeq, Carlin Chuck, Rahul A Sastry, Rohaid Ali, Clark C Chen

J Clin Med· January 2025

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Neuro-oncology application of next-generation, optically tracked robotic stereotaxis with intraoperative computed tomography: a pilot experience.
Carlin Chuck, Rohaid Ali, Christine K Lee, Athar N Malik, Konstantina A Svokos, Clark C Chen

Neurosurg Focus· December 2024

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Patient-reported outcome and preference after craniotomy and laser interstitial thermal therapy ablation: a pilot study.
Isabela Peña Pino, Jiri Bartek, Sharona Ben-Haim, Clark C Chen

Neurosurg Focus· November 2024

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Cell migration simulator-based biomarkers for glioblastoma.
Jay Hou, Mariah McMahon, Tyler Jubenville, Jann N Sarkaria, Clark C Chen

Neurooncol Adv· November 2024

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"Doctor, What Would You do if You Were Me?" - A Survey of Physician Perspectives Toward Glioblastoma Resection.
Bayard Wilson, Crina M Peterson, Hua Wei, Mao Ying, Jiri Bartek, Clark C Chen

World Neurosurg· October 2024

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Early experience and perioperative risk of GammaTile for upfront brain metastases: Report from a prospective multicenter study.
Sabrina L Zeller, Sauson Soldozy, Shaye Busse, Clark C Chen, Andrew Venteicher

Neurooncol Adv· September 2024

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Directionally non-rotating electric field therapy delivered through implanted electrodes as a glioblastoma treatment platform: A proof-of-principle study.
Jun Ma, Shilpi Singh, Ming Li, Davis Seelig, Gregory F Molnar, David Chen, Clark C Chen

Neurooncol Adv· July 2024

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The ClearPoint Prism® Laser Ablation System: A New Platform for Laser Interstitial Thermal Therapy (LITT) in Neuro-Oncology.
Hannah Wilson, Sanjay Dhawan, Truong Huy Do, Samuel H Jones, Clark C Chen

Neurosurg Pract· March 2024

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