Publications by authors named "D Machover"

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The methioninase from the alkalithermophile Thermobrachium celere possesses suitable properties for treatment of cancer.
Nathan Ferchaud, David Kopečný, Miroslav Peřina, Angélique Boyer, Sihem Hentati, David Machover

Int J Biol Macromol· November 2025

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Treatment of patients with carcinomas in advanced stages with 5-fluorouracil, folinic acid and pyridoxine in tandem.
David Machover, Wathek Almohamad, Vincent Castagné, Christophe Desterke, Léa Gomez

Sci Rep· May 2024

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PLP-Dependent Enzyme Methionine γ-Lyase: Insights into the Michaelis Complex from Molecular Dynamics and Free Energy Simulations.
Xingyu Chen, Nathan Ferchaud, Pierre Briozzo, David Machover, Thomas Simonson

Biochemistry· September 2023

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Pharmacologic modulation of 5-fluorouracil by folinic acid and pyridoxine for treatment of patients with advanced breast carcinoma.
David Machover, Emma Goldschmidt, Wathek Almohamad, Vincent Castagné, Julien Dairou

Sci Rep· May 2022

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A Computational Model for the PLP-Dependent Enzyme Methionine -Lyase.
Xingyu Chen, Pierre Briozzo, David Machover, Thomas Simonson

Front Mol Biosci· April 2022

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