Publications by authors named "D V Subbaiah"

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Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease.
Katsutoshi Sato, Amol A Padgaonkar, Stacey J Baker, Stephen C Cosenza, Olga Rechkoblit, D R C Venkata Subbaiah

Nat Commun· August 2021

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Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5).
M V Ramana Reddy, Balireddy Akula, Stephen C Cosenza, Saikrishna Athuluridivakar, Muralidhar R Mallireddigari, D R C Venkata Subbaiah

J Med Chem· February 2014

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Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.
M V Ramana Reddy, Muralidhar R Mallireddigari, Venkat R Pallela, Stephen C Cosenza, Vinay K Billa, D R C Venkata Subbaiah

J Med Chem· July 2013

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Hydrothiolation of benzyl mercaptan to arylacetylene: application to the synthesis of (E) and (Z)-isomers of ON 01910·Na (Rigosertib®), a phase III clinical stage anti-cancer agent.
Venkat R Pallela, Muralidhar R Mallireddigari, Stephen C Cosenza, Balaiah Akula, D R C Venkata Subbaiah

Org Biomol Chem· March 2013

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(Z)-1-aryl-3-arylamino-2-propen-1-ones, highly active stimulators of tubulin polymerization: synthesis, structure-activity relationship (SAR), tubulin polymerization, and cell growth inhibition studies.
M V Ramana Reddy, Balaiah Akula, Stephen C Cosenza, Clement M Lee, Muralidhar R Mallireddigari, D R C Venkata Subbaiah

J Med Chem· June 2012

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