Publications by authors named "Daniel Ajona"

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Fasting and fasting-mimicking conditions in the cancer immunotherapy era.
Ruben Pio, Yaiza Senent, Beatriz Tavira, Daniel Ajona

J Physiol Biochem· May 2025

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Insights and perspectives into the discovery of complement-related biomarkers in cancer.
Daniel Ajona, Janire Debersaques, Ruben Pio

Curr Opin Immunol· October 2025

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Dual ENPP1/ATM depletion blunts DNA damage repair boosting radioimmune efficacy to abrogate triple-negative breast cancer.
Borja Ruiz-Fernández de Córdoba, Karmele Valencia, Connor Welch, Haritz Moreno, Susana Martínez-Canarias, Daniel Ajona

Signal Transduct Target Ther· June 2025

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A mouse model to assess immunotherapy-related colitis.
Yaiza Senent, Ana Remírez, Beatriz Tavira, Daniel Ajona

Methods Cell Biol· May 2025

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Co-targeting of epigenetic regulators and BCL-XL improves efficacy of immune checkpoint blockade therapy in multiple solid tumors.
Yaiza Senent, Vicente Fresquet, Victoria Jiménez, Karmele Valencia, Francisco Exposito, Daniel Ajona

Mol Cancer· May 2025

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The C5a/C5aR1 Axis Promotes Migration of Tolerogenic Dendritic Cells to Lymph Nodes, Impairing the Anticancer Immune Response.
Yaiza Senent, Ana Remírez, David Repáraz, Diana Llopiz, Daiana P Celias, Daniel Ajona

Cancer Immunol Res· March 2025

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The complement system in clinical oncology: Applications, limitations and challenges.
Daniel Ajona, Mark S Cragg, Ruben Pio

Semin Immunol· March 2025

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Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation.
Ander Puyalto, María Rodríguez-Remírez, Inés López, Irati Macaya, Elizabeth Guruceaga, Daniel Ajona

Mol Cancer· April 2024

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A novel [Zr]-anti-PD-1-PET-CT to assess response to PD-1/PD-L1 blockade in lung cancer.
Ander Puyalto, María Rodríguez-Remírez, Inés López, Fabiola Iribarren, Jon Ander Simón, Daniel Ajona

Front Immunol· October 2023

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Plasma fractalkine contributes to systemic myeloid diversity and PD-L1/PD-1 blockade in lung cancer.
Ana Bocanegra, Gonzalo Fernández-Hinojal, Daniel Ajona, Ester Blanco, Miren Zuazo

EMBO Rep· August 2023

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The complement system as a regulator of tumor-promoting activities mediated by myeloid-derived suppressor cells.
Yaiza Senent, Beatriz Tavira, Ruben Pio, Daniel Ajona

Cancer Lett· November 2022

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Gemcitabine-mediated depletion of immunosuppressive dendritic cells enhances the efficacy of therapeutic vaccination.
David Repáraz, Marta Ruiz, Leyre Silva, Belén Aparicio, Josune Egea, Daniel Ajona

Front Immunol· October 2022

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Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer.
Borja Ruiz-Fernández de Córdoba, Haritz Moreno, Karmele Valencia, Naiara Perurena, Pablo Ruedas, Daniel Ajona

Cancer Discov· May 2022

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Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis.
Sergio Ortiz-Espinosa, Xabier Morales, Yaiza Senent, Diego Alignani, Beatriz Tavira, Daniel Ajona

Cancer Lett· March 2022

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Persistence of High Levels of Serum Complement C5a in Severe COVID-19 Cases After Hospital Discharge.
Yaiza Senent, Susana Inogés, Ascensión López-Díaz de Cerio, Andres Blanco, Arantxa Campo, Daniel Ajona

Front Immunol· January 2022

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Two cell line models to study multiorganic metastasis and immunotherapy in lung squamous cell carcinoma.
Karmele Valencia, Cristina Sainz, Cristina Bértolo, Gabriel de Biurrun, Jackeline Agorreta, Daniel Ajona

Dis Model Mech· January 2022

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A model based on the quantification of complement C4c, CYFRA 21-1 and CRP exhibits high specificity for the early diagnosis of lung cancer.
Daniel Ajona, Ana Remirez, Cristina Sainz, Cristina Bertolo, Alvaro Gonzalez

Transl Res· July 2021

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The Complement System in Ovarian Cancer: An Underexplored Old Path.
Yaiza Senent, Daniel Ajona, Antonio González-Martín, Ruben Pio, Beatriz Tavira

Cancers (Basel)· July 2021

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Characterization of the perioperative changes of exosomal immune-related cytokines induced by prostatectomy in early-stage prostate cancer patients.
Mónica Macías, Ángel García-Cortés, Marcos Torres, Javier Ancizu-Marckert, Juan Ignacio Pascual, Daniel Ajona

Cytokine· May 2021

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SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation.
Esther Redin, Irati Garmendia, Teresa Lozano, Diego Serrano, Yaiza Senent, Daniel Ajona

J Immunother Cancer· March 2021

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Molecular biomarkers in early stage lung cancer.
María Rodríguez, Daniel Ajona, Luis M Seijo, Julián Sanz, Karmele Valencia

Transl Lung Cancer Res· February 2021

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Id1 and PD-1 Combined Blockade Impairs Tumor Growth and Survival of -mutant Lung Cancer by Stimulating PD-L1 Expression and Tumor Infiltrating CD8 T Cells.
Iosune Baraibar, Marta Roman, María Rodríguez-Remírez, Inés López, Anna Vilalta, Daniel Ajona

Cancers (Basel)· October 2020

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Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion.
Alejandro Athie, Francesco P Marchese, Jovanna González, Teresa Lozano, Ivan Raimondi, Daniel Ajona

J Cell Biol· September 2020

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Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade.
Daniel Ajona, Sergio Ortiz-Espinosa, Teresa Lozano, Francisco Exposito, Alfonso Calvo

Nat Cancer· January 2020

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YES1 Drives Lung Cancer Growth and Progression and Predicts Sensitivity to Dasatinib.
Irati Garmendia, María J Pajares, Francisco Hermida-Prado, Daniel Ajona, Cristina Bértolo

Am J Respir Crit Care Med· October 2019

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