Publications by authors named "Daniel Wacker"

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Crystal Structure of an LSD-Bound Human Serotonin Receptor.
Daniel Wacker, Sheng Wang, John D McCorvy, Robin M Betz, A J Venkatakrishnan, Anat Levit, Katherine Lansu, Zachary L Schools, Tao Che, David E Nichols

January 2017

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A comprehensive analysis of jurisdiction-specific laws related to scheduling or required prescription drug monitoring of gabapentin in the United States, 2016-2024.
Katherine Gora Combs, Rachel Vickers-Smith, Collin Stewart, Daniel Wacker, Juan M Hincapie-Castillo

Int J Drug Policy· December 2025

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Structural and dynamic studies uncover a distinct allosteric modulatory site at the μ-opioid receptor.
Haonan Zhang, Kirill Konovalov, Alexandra K Parpounas, Davide Provasi, Shifan Yang, Daniel Wacker

bioRxiv· October 2025

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Structural determinants of G protein subtype selectivity at the serotonin receptor 5-HT1A.
Audrey L Warren, Gregory Zilberg, Anwar Abbassi, Alejandro Abraham, Shifan Yang, Daniel Wacker

Sci Adv· August 2025

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Biased Signaling in Psychedelic Action.
Daniel Wacker, John D McCorvy

Annu Rev Pharmacol Toxicol· August 2025

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Can Targeting the Sodium Site via Water Molecules Lead to the Development of Safer Opioids?
Daniel Wacker, Marta Filizola

ACS Cent Sci· August 2024

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Structural pharmacology and therapeutic potential of 5-methoxytryptamines.
Audrey L Warren, David Lankri, Michael J Cunningham, Inis C Serrano, Lyonna F Parise, Daniel Wacker

Nature· June 2024

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Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HTR and 5-HTR.
Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Bianca Fiorillo, Davide Provasi, Daniel Wacker

Sci Adv· April 2024

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Molecular basis of human trace amine-associated receptor 1 activation.
Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Shifan Yang, Daniel Wacker

Nat Commun· January 2024

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Substrate binding and inhibition of the anion exchanger 1 transporter.
Michael J Capper, Shifan Yang, Alexander C Stone, Sezen Vatansever, Gregory Zilberg, Daniel Wacker

Nat Struct Mol Biol· October 2023

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Structural Insights into the Unexpected Agonism of Tetracyclic Antidepressants at Serotonin Receptors 5-HT1eR and 5-HT1FR.
Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Bianca Fiorillo, Davide Provasi, Daniel Wacker

bioRxiv· October 2023

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Molecular insights into GPCR mechanisms for drugs of abuse.
Omar B Sanchez-Reyes, Gregory Zilberg, John D McCorvy, Daniel Wacker

J Biol Chem· September 2023

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Molecular Basis of Human Trace Amine-Associated Receptor 1 Activation.
Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Shifan Yang, Daniel Wacker

bioRxiv· September 2023

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A Regional and Projection-Specific Role of RGSz1 in the Ventrolateral Periaqueductal Grey in the Modulation of Morphine Reward.
Farhana Sakloth, Omar B Sanchez-Reyes, Anne Ruiz, Andrew Nicolais, Randal A Serafini, Daniel Wacker

Mol Pharmacol· January 2023

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Artificial intelligence and machine learning-aided drug discovery in central nervous system diseases: State-of-the-arts and future directions.
Sezen Vatansever, Avner Schlessinger, Daniel Wacker, H Ümit Kaniskan, Jian Jin

Med Res Rev· May 2021

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Effects of the Minimal Extrathyroidal Extension on Early Response Rates after (Adjuvant) Initial Radioactive Iodine Therapy in PTC Patients.
Freba Ahmaddy, Vera Wenter, Harun Ilhan, Daniel Wacker, Marcus Unterrainer

Cancers (Basel)· November 2020

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Structure of a Hallucinogen-Activated Gq-Coupled 5-HT Serotonin Receptor.
Kuglae Kim, Tao Che, Ouliana Panova, Jeffrey F DiBerto, Jiankun Lyu, Daniel Wacker

Cell· September 2020

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A Novel Cryo-EM Structure Enables Development of Selective Cannabinoid Receptor Drugs.
Gregory Zilberg, Daniel Wacker

Biochemistry· May 2020

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Nanobody-enabled monitoring of kappa opioid receptor states.
Tao Che, Justin English, Brian E Krumm, Kuglae Kim, Els Pardon, Daniel Wacker

Nat Commun· March 2020

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VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells.
Justin G English, Reid H J Olsen, Katherine Lansu, Michael Patel, Karoline White, Daniel Wacker

Cell· August 2019

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VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells.
Justin G English, Reid H J Olsen, Katherine Lansu, Michael Patel, Karoline White, Daniel Wacker

Cell· July 2019

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Structural determinants of 5-HT receptor activation and biased agonism.
John D McCorvy, Daniel Wacker, Sheng Wang, Bemnat Agegnehu, Jing Liu

Nat Struct Mol Biol· September 2018

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How the ubiquitous GPCR receptor family selectively activates signalling pathways.
Michael J Capper, Daniel Wacker

Nature· June 2018

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Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone.
Sheng Wang, Tao Che, Anat Levit, Brian K Shoichet, Daniel Wacker

Nature· March 2018

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5-HT Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.
Yao Peng, John D McCorvy, Kasper Harpsøe, Katherine Lansu, Shuguang Yuan, Daniel Wacker

Cell· February 2018

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Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
Tao Che, Susruta Majumdar, Saheem A Zaidi, Pauline Ondachi, John D McCorvy, Daniel Wacker

Cell· January 2018

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