Publications by authors named "Darren Baker"

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Protein kinase Cι dictates tumor trajectory, cell plasticity, and immune surveillance in lung adenocarcinoma.
Duy T Nguyen, Luis I Prieto, Cheng Zhang, Hu Li, Andras Khoor, Darren J Baker

Cell Rep· December 2025

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The Sixth Annual Symposium of the Midwest Aging Consortium.
Ines Sturmlechner, Sarah A Ashiqueali, Hélène Martini, Karla Valdivieso, Ana Catarina Franco, Darren J Baker

J Gerontol A Biol Sci Med Sci· December 2025

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An Unbiased Cell-Culture Selection Yields DNA Aptamers as Novel Senescent Cell-Specific Reagents.
Keenan S Pearson, Sarah K Jachim, Caroline D Doherty, Brandon A Wilbanks, Luis I Prieto, Darren J Baker

Aging Cell· November 2025

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Advancing biological understanding of cellular senescence with computational multiomics.
Sheng Li, Paula A Agudelo Garcia, Constantin Aliferis, Michael J Becich, Jazmin Calyeca, Darren J Baker

Nat Genet· October 2025

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Protocol to test path integration in mice using an L-maze behavioral assay.
Sara I Graves, Darren J Baker

STAR Protoc· October 2025

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BubR1 Insufficiency Drives Transcriptomic Alterations and Pathology Associated With Cardiac Aging and Heart Failure.
Renju Pun, Aliya L Haas, Aradhana Thapa, Sylar R Takafuji, Rexton M Suzuki, Darren J Baker

Aging Cell· September 2025

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Evaluation of [F]F-CNBI and [F]F-CNPI PET Probes in GSK-3β Transgenic Mice.
Manasa Kethamreddy, Surendra Reddy Gundam, Andy Gonzalez Rivera, Aditya Bansal, Do Young Lim, Darren J Baker

ACS Chem Neurosci· September 2025

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Single-cell and spatial transcriptomics map senescent vascular cells in arterial remodeling during atherosclerosis in mice.
Krystyna Mazan-Mamczarz, Dimitrios Tsitsipatis, Bennett G Childs, Angelica E Carr, Carla Rocha Dos Santos, Darren J Baker

Nat Aging· August 2025

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p16-expressing microglia and endothelial cells promote tauopathy and neurovascular abnormalities in PS19 mice.
Sara I Graves, Charlton F Meyer, Karthik B Jeganathan, Darren J Baker

Neuron· July 2025

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Neuroinflammation in Alzheimer disease.
Michael T Heneka, Wiesje M van der Flier, Frank Jessen, Jeroen Hoozemanns, Dietmar Rudolf Thal, Darren J Baker

Nat Rev Immunol· May 2025

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An unbiased cell-culture selection yields DNA aptamers as novel senescent cell-specific reagents.
Keenan S Pearson, Sarah K Jachim, Caroline D Doherty, Brandon A Wilbanks, Luis I Prieto, Darren J Baker

bioRxiv· March 2025

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IL-23R is a senescence-linked circulating and tissue biomarker of aging.
Chase M Carver, Sonia L Rodriguez, Elizabeth J Atkinson, Andrew J Dosch, Niels C Asmussen, Darren J Baker

Nat Aging· February 2025

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Chronic social stress induces p16-mediated senescent cell accumulation in mice.
Carey E Lyons, Jean Pierre Pallais, Seth McGonigle, Rachel P Mansk, Charles W Collinge, Darren J Baker

Nat Aging· January 2025

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SenNet recommendations for detecting senescent cells in different tissues.
Vidyani Suryadevara, Adam D Hudgins, Adarsh Rajesh, Alberto Pappalardo, Alla Karpova, Darren J Baker

Nat Rev Mol Cell Biol· December 2024

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Gene deletion of Pregnancy-associated Plasma Protein-A (PAPP-A) improves pathology and cognition in an Alzheimer's disease mouse model.
Laurie K Bale, Sally A West, Naomi M Gades, Darren J Baker, Cheryl A Conover

Exp Neurol· December 2024

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Loss of HD-PTP function results in lipodystrophy, defective cellular signaling and altered lipid homeostasis.
Destiny F Schultz, Brian A Davies, Johanna A Payne, Cole P Martin, Annabel Y Minard, Darren J Baker

J Cell Sci· September 2024

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Guidelines for minimal information on cellular senescence experimentation in vivo.
Mikolaj Ogrodnik, Juan Carlos Acosta, Peter D Adams, Fabrizio d'Adda di Fagagna, Darren J Baker

Cell· August 2024

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Chronic Social and Psychological Stress Impact Select Neuropathologies in the PS19 Mouse Model of Tauopathy.
Carey E Lyons, Sara I Graves, Maria Razzoli, Karthik Jeganathan, Rachel P Mansk, Darren J Baker

Psychosom Med· June 2024

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Senescent Macrophages Release Inflammatory Cytokines and RNA-Loaded Extracellular Vesicles to Circumvent Fibroblast Senescence.
Camille Laliberté, Bianca Bossé, Véronique Bourdeau, Luis I Prieto, Genève Perron-Deshaies, Darren J Baker

Biomedicines· May 2024

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Caloric Restriction Improves Spatial Learning Deficits in Tau Mice.
Valeria Cogut, Taylor L McNeely, Tyler J Bussian, Sara I Graves, Darren J Baker

J Alzheimers Dis· April 2024

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Senescence Targeting Methods Impact Alzheimer's Disease Features in 3xTg Mice.
Pei Y Ng, Cheng Zhang, Hu Li, Darren J Baker

J Alzheimers Dis· February 2024

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Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence.
Margaret Johnson, April Bell, Kristen L Lauing, Erik Ladomersky, Lijie Zhai, Darren J Baker

Clin Cancer Res· December 2023

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An untapped window of opportunity for glioma: targeting therapy-induced senescence prior to recurrence.
Cecile Riviere-Cazaux, Lucas P Carlstrom, Bryan J Neth, Ian E Olson, Karishma Rajani, Darren J Baker

NPJ Precis Oncol· November 2023

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Senescent Microglia Represent a Subset of Disease-Associated Microglia in P301S Mice.
Pei Y Ng, Cheng Zhang, Hu Li, Darren J Baker

J Alzheimers Dis· September 2023

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Senescent cells as thermostats of antitumor immunity.
Luis I Prieto, Ines Sturmlechner, Jörg J Goronzy, Darren J Baker

Sci Transl Med· June 2023

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