Publications by authors named "David A Knorr"

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Fc-optimized CD40 agonistic antibody elicits tertiary lymphoid structure formation and systemic antitumor immunity in metastatic cancer.
Juan C Osorio, David A Knorr, Polina Weitzenfeld, Lucas Blanchard, Ning Yao, Maria Baez, Carlo Sevilla, Meghan DiLillo, Jahan Rahman, Ved P Sharma

October 2025

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Mucin 16-Directed Therapy in Pediatric Sarcomas: Case Evidence of Ubamatamab Efficacy in Epithelioid Sarcoma and Its Implications for Other Sarcoma Subtypes.
Denise M Connolly, Gabriel Revon-Rivière, Rose Chami, Denise Mills, Ailish C Coblentz, David A Knorr

JCO Precis Oncol· August 2025

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Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade.
Lucas Blanchard, Estefania Vina, Jerko Ljubetic, Cécile Meneur, Dorian Tarroux, David A Knorr

Cell Rep Med· June 2025

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Intratumoral Fc-optimized agonistic CD40 antibody induces tumor rejection and systemic antitumor immunity in patients with metastatic cancer.
Juan C Osorio, David A Knorr, Polina Weitzenfeld, Ning Yao, Maria Baez

Res Sq· June 2024

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FcγRIIB Is an Immune Checkpoint Limiting the Activity of Treg-Targeting Antibodies in the Tumor Microenvironment.
David A Knorr, Lucas Blanchard, Rom S Leidner, Shawn M Jensen, Ryan Meng

Cancer Immunol Res· March 2024

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The antitumor activities of anti-CD47 antibodies require Fc-FcγR interactions.
Juan C Osorio, Patrick Smith, David A Knorr, Jeffrey V Ravetch

Cancer Cell· December 2023

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IL-15 synergizes with CD40 agonist antibodies to induce durable immunity against bladder cancer.
Jeffrey L Wong, Patrick Smith, Juan Angulo-Lozano, Daniel Ranti, Bernard H Bochner, David A Knorr

Proc Natl Acad Sci U S A· August 2023

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The Antitumor Activities of Anti-CD47 Antibodies Require Fc-FcγR interactions.
Juan C Osorio, Patrick Smith, David A Knorr, Jeffrey V Ravetch

bioRxiv· June 2023

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Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models.
Scott Parker, Charlotte McDowall, Luis Sanchez-Perez, Cristina Osorio, Patrick C Duncker, David A Knorr

Sci Transl Med· February 2023

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IL-15 synergizes with CD40 agonist antibodies to induce durable immunity against bladder cancer.
Jeffrey L Wong, Patrick Smith, Juan Angulo-Lozano, Daniel Ranti, Bernard H Bochner, David A Knorr

bioRxiv· February 2023

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PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine.
Ramin Sedaghat Herati, David A Knorr, Laura A Vella, Luisa Victoria Silva, Lakshmi Chilukuri

Nat Immunol· August 2022

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Disease- and Therapy-Specific Impact on Humoral Immune Responses to COVID-19 Vaccination in Hematologic Malignancies.
David J Chung, Gunjan L Shah, Sean M Devlin, Lakshmi V Ramanathan, Sital Doddi, David A Knorr

Blood Cancer Discov· November 2021

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Predictors of Humoral Response to SARS-CoV-2 Vaccination after Hematopoietic Cell Transplantation and CAR T-cell Therapy.
Roni Tamari, Ioannis Politikos, David A Knorr, Santosha A Vardhana, Jennifer C Young

Blood Cancer Discov· November 2021

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Differentiation syndrome-induced Myopericarditis in the induction therapy of acute Promyelocytic leukemia: a case report.
Shabari Mangalore Shenoy, Thomas Di Vitantonio, Anna Plitt, Rocio Perez-Johnston, Jillian Gutierrez, David A Knorr

Cardiooncology· November 2021

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COVID-19 vaccine efficacy in patients with chronic lymphocytic leukemia.
Lindsey E Roeker, David A Knorr, Meghan C Thompson, Mariely Nivar, Sonia Lebowitz

Leukemia· September 2021

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Pharmacologic modulation of RNA splicing enhances anti-tumor immunity.
Sydney X Lu, Emma De Neef, James D Thomas, Erich Sabio, Benoit Rousseau, David A Knorr

Cell· July 2021

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Site-Selective Chemoenzymatic Modification on the Core Fucose of an Antibody Enhances Its Fcγ Receptor Affinity and ADCC Activity.
Chao Li, Gene Chong, Guanghui Zong, David A Knorr, Stylianos Bournazos

J Am Chem Soc· May 2021

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Dendritic cell targeting with Fc-enhanced CD40 antibody agonists induces durable antitumor immunity in humanized mouse models of bladder cancer.
Christopher S Garris, Jeffrey L Wong, Jeffrey V Ravetch, David A Knorr

Sci Transl Med· May 2021

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Anti-SARS-CoV-2 antibody response in patients with chronic lymphocytic leukemia.
Lindsey E Roeker, David A Knorr, Melissa S Pessin, Lakshmi V Ramanathan, Meghan C Thompson

Leukemia· November 2020

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Spontaneous Remission in a Patient With Acute Myeloid Leukemia Leading to Undetectable Minimal Residual Disease.
Daniel Helbig, Andres E Quesada, Wenbin Xiao, Mikhail Roshal, Martin S Tallman, David A Knorr

J Hematol· April 2020

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Immunotherapy for acute myeloid leukemia: from allogeneic stem cell transplant to novel therapeutics.
David A Knorr, Aaron D Goldberg, Eytan M Stein, Martin S Tallman

Leuk Lymphoma· December 2019

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Immunotherapy and Hyperprogression: Unwanted Outcomes, Unclear Mechanism.
David A Knorr, Jeffrey V Ravetch

Clin Cancer Res· February 2019

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Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity.
David A Knorr, Rony Dahan, Jeffrey V Ravetch

Proc Natl Acad Sci U S A· October 2018

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Loss of T Follicular Helper Cells in the Peripheral Blood of Patients with Chronic Graft-versus-Host Disease.
David A Knorr, Hongbo Wang, Mukta Aurora, Margaret L MacMillan, Shernan G Holtan

Biol Blood Marrow Transplant· May 2016

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Clinical utility of natural killer cells in cancer therapy and transplantation.
David A Knorr, Veronika Bachanova, Michael R Verneris, Jeffrey S Miller

Semin Immunol· April 2014

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