Publications by authors named "David Altshuler"

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CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia.
Haydar Frangoul, David Altshuler, M Domenica Cappellini, Yi-Shan Chen, Jennifer Domm, Brenda K Eustace, Juergen Foell, Josu de la Fuente, Stephan Grupp, Rupert Handgretinger

January 2021

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Specificity of CRISPR-Cas9 Editing in Exagamglogene Autotemcel - Update.
Angela Yen, Tony Boitano, Zachary Zappala, Sudipta Mahajan, Thomas Willems, David Altshuler

N Engl J Med· October 2025

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A Phase 2 Study of Multiparametric Magnetic Resonance Imaging-Guided High-Dose Response-Adaptive Radiation Therapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma: Results From an Interim Analysis.
Michelle M Kim, Madhava P Aryal, Krithika Suresh, Benjamin S Rosen, Hemant Parmar, David Altshuler

Int J Radiat Oncol Biol Phys· July 2025

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Specificity of CRISPR-Cas9 Editing in Exagamglogene Autotemcel.
Angela Yen, Zachary Zappala, Rebecca S Fine, Timothy D Majarian, Parin Sripakdeevong, David Altshuler

N Engl J Med· May 2024

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Step-by-Step Dissection of the Extreme Lateral Transodontoid Approach to the Anterior Craniovertebral Junction: Surgical Anatomy and Technical Nuances.
Irakliy Abramov, Mohamed A Labib, David Altshuler, Lena Mary Houlihan, Nicolas I Gonzalez-Romo

World Neurosurg· February 2024

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Corrigendum to "Ventricular Volume Change as a Predictor of Shunt-Dependent Hydrocephalus in Aneurysmal Subarachnoid Hemorrhage" [World Neurosurgery (2022) 17880].
Haley K Talbot-Stetsko, Kristen D Pawlowski, Bryan L Aaron, Arjun R Adapa, David B Altshuler

World Neurosurg· December 2023

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Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.
Yoshie Umemura, Daniel Orringer, Larry Junck, Maria L Varela, Molly E J West, David Altshuler

Lancet Oncol· September 2023

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The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits.
Maria C Costanzo, Marcin von Grotthuss, Jeffrey Massung, Dongkeun Jang, Lizz Caulkins, David Altshuler

Cell Metab· April 2023

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Inaxaplin for Proteinuric Kidney Disease in Persons with Two Variants.
Ogo Egbuna, Brandon Zimmerman, George Manos, Anne Fortier, Madalina C Chirieac, David Altshuler

N Engl J Med· March 2023

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Anterior petrosal (Kawase) approach to petroclival meningioma: 2-dimensional operative video.
Eva M Wu, David Altshuler, Stephanie H Chen, Jacques J Morcos

Neurosurg Focus Video· April 2022

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Exercise improves health-related quality of life sleep and fatigue domains in adult high- and low-grade glioma patients.
Zachary Miklja, Nicolette Gabel, David Altshuler, Lin Wang, Shawn L Hervey-Jumper

Support Care Cancer· February 2022

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Ventricular Volume Change as a Predictor of Shunt-Dependent Hydrocephalus in Aneurysmal Subarachnoid Hemorrhage.
Haley K Talbot-Stetsko, Kristen D Pawlowski, Bryan L Aaron, Arjun R Adapa, David B Altshuler

World Neurosurg· January 2022

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Imaging Errors in Distinguishing Pituitary Adenomas From Other Sellar Lesions.
David B Altshuler, Chris A Andrews, Hemant A Parmar, Stephen E Sullivan, Jonathan D Trobe

J Neuroophthalmol· December 2021

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Vascular compromise in a torsed transposed ulnar nerve case in support of intravenous contrast administration.
Yoav Morag, David Altshuler, Kara Udager, Lynda C Yang

Clin Imaging· February 2021

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Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.
Vasiliki Lagou, Reedik Mägi, Jouke- Jan Hottenga, Harald Grallert, John R B Perry, David Altshuler

Nat Commun· February 2021

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Functional characterization of tumor antigen-specific T-cells isolated from the tumor microenvironment of sleeping beauty induced murine glioma models.
Mahmoud S Alghamri, Felipe J Núñez, Neha Kamran, Stephen Carney, David Altshuler

Methods Enzymol· January 2021

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Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.
Vasiliki Lagou, Reedik Mägi, Jouke- Jan Hottenga, Harald Grallert, John R B Perry, David Altshuler

Nat Commun· January 2021

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Isolation and characterization of immune cells from the tumor microenvironment of genetically engineered pediatric high-grade glioma models using the sleeping beauty transposon system.
Maria Belen Garcia-Fabiani, Andrea Comba, Padma Kadiyala, Santiago Haase, Felipe Javier Núñez, David Altshuler

Methods Enzymol· December 2020

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Normal cerebral ventricular volume growth in childhood.
Noah S Cutler, Sudharsan Srinivasan, Bryan L Aaron, Sharath Kumar Anand, Michael S Kang, David B Altshuler

J Neurosurg Pediatr· November 2020

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Using a Mobile Application for Evaluation of Procedural Learning in Neurosurgery.
Sravanthi Koduri, David B Altshuler, Siri Sahib S Khalsa, Cormac O Maher, Greg Wnuk

World Neurosurg· June 2020

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Prospects of biological and synthetic pharmacotherapies for glioblastoma.
David B Altshuler, Padma Kadiyala, Felipe J Nuñez, Fernando M Nuñez, Stephen Carney

Expert Opin Biol Ther· March 2020

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, , and polymorphisms and ability to return to work in adult patients with low- and high-grade glioma.
David B Altshuler, Lin Wang, Lili Zhao, Zachary Miklja, Joey Linzey

Neurooncol Pract· September 2019

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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
Jason Flannick, Josep M Mercader, Christian Fuchsberger, Miriam S Udler, Anubha Mahajan, David Altshuler

Nature· June 2019

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Health Related Quality of Life in Adult Low and High-Grade Glioma Patients Using the National Institutes of Health Patient Reported Outcomes Measurement Information System (PROMIS) and Neuro-QOL Assessments.
Nicolette Gabel, David B Altshuler, Amanda Brezzell, Emily M Briceño, Nicholas R Boileau

Front Neurol· March 2019

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High-Density Lipoprotein-Mimicking Nanodiscs for Chemo-immunotherapy against Glioblastoma Multiforme.
Padma Kadiyala, Dan Li, Fernando M Nuñez, David Altshuler, Robert Doherty

ACS Nano· February 2019

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