Publications by authors named "David Demets"

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Dapagliflozin in heart failure with preserved and mildly reduced ejection fraction: rationale and design of the DELIVER trial.
Scott D Solomon, Rudolf A de Boer, David DeMets, Adrian F Hernandez, Silvio E Inzucchi, Mikhail N Kosiborod, Carolyn S P Lam, Felipe Martinez, Sanjiv J Shah, Daniel Lindholm

Eur J Heart Fail· July 2021

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Response to Cleland and Anzar.
Janet Wittes, David L DeMets, KyungMann Kim, Dennis G Maki, Marc A Pfeffer

Clin Trials· August 2025

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Aspirin in primary prevention: Undue reliance on an uninformative trial led to misinformed clinical guidelines.
Janet Wittes, David L DeMets, KyungMann Kim, Dennis G Maki, Marc A Pfeffer

Clin Trials· August 2025

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Symptoms Burden as a Clinical Outcomes Assessment in Heart Failure Patients With Atrial Fibrillation.
Ian A Carroll, Jonathan P Piccini, Benjamin A Steinberg, Wendy S Tzou, Jennifer C Richards, David L DeMets

JACC Heart Fail· April 2025

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Society for Clinical Trials Data Monitoring Committee initiative website: Closing the gap.
David L DeMets, Susan Halabi, Lehana Thabane, Janet Wittes

Clin Trials· December 2024

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The Case for Access to Data Monitoring Committee Charters.
Deborah Zarin, Janet T Wittes, Thomas R Fleming, Frank Rockhold, Susan Ellenberg, David L DeMets

NEJM Evid· September 2024

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Training the Next Generation of Data Monitoring Committee Members: An Initiative of the Heart Failure Collaboratory.
Thomas R Fleming, Janet Wittes, Mona Fiuzat, Michael R Bristow, Frank W Rockhold, David L DeMets

JACC Heart Fail· August 2024

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Guidance for Healthcare Providers on Newest Guidelines for Over-the-Counter Drug Treatment of Mild Symptoms of COVID-19.
Gage Collamore, Mark J DiCorcia, Yash Nagpal, Lawrence Fiedler, Michael A Garone, David L DeMets

Am J Med· June 2024

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Training New DMC Members: A Call to Action.
Frank Rockhold, Kenneth Mahaffey, David DeMets

Ther Innov Regul Sci· March 2024

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Author Correction: Dapagliflozin in heart failure with improved ejection fraction: a prespecified analysis of the DELIVER trial.
Orly Vardeny, James C Fang, Akshay S Desai, Pardeep S Jhund, Brian Claggett, David DeMets

Nat Med· December 2023

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Bringing data monitoring committee charters into the sunlight.
David L DeMets, Deborah A Zarin, Frank Rockhold, Susan S Ellenberg, Thomas Fleming

Clin Trials· August 2023

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The Data Monitoring Committee: A Collective or a Collection?
Janet Wittes, Thomas Fleming, David DeMets, Susan Ellenberg, Hertzel Gerstein

Ther Innov Regul Sci· July 2023

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Dapagliflozin in heart failure with improved ejection fraction: a prespecified analysis of the DELIVER trial.
Orly Vardeny, James C Fang, Akshay S Desai, Pardeep S Jhund, Brian Claggett, David DeMets

Nat Med· December 2022

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Efficacy and Safety of Dapagliflozin in Heart Failure With Mildly Reduced or Preserved Ejection Fraction According to Age: The DELIVER Trial.
Alexander Peikert, Felipe A Martinez, Muthiah Vaduganathan, Brian L Claggett, Ian J Kulac, David DeMets

Circ Heart Fail· October 2022

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Dapagliflozin in Patients Recently Hospitalized With Heart Failure and Mildly Reduced or Preserved Ejection Fraction.
Jonathan W Cunningham, Muthiah Vaduganathan, Brian L Claggett, Ian J Kulac, Akshay S Desai, David DeMets

J Am Coll Cardiol· October 2022

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Experiences of the Data Monitoring Committee for the RECOVERY trial, a large-scale adaptive platform randomised trial of treatments for patients hospitalised with COVID-19.
Peter A G Sandercock, Janet Darbyshire, David DeMets, Robert Fowler, David G Lalloo

Trials· October 2022

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Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction.
Scott D Solomon, John J V McMurray, Brian Claggett, Rudolf A de Boer, David DeMets

N Engl J Med· September 2022

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Dapagliflozin across the range of ejection fraction in patients with heart failure: a patient-level, pooled meta-analysis of DAPA-HF and DELIVER.
Pardeep S Jhund, Toru Kondo, Jawad H Butt, Kieran F Docherty, Brian L Claggett, David DeMets

Nat Med· September 2022

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Updates for Health Providers on Monoclonal Antibodies for COVID-19: Less Promising Adjunct and Never an Alternative to Vaccinations.
Maja Berges, Keith Foster, Jennifer Foster, Lisa Martinez, Sean Martinez, David L DeMets

Am J Med· May 2022

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Ivermectin in COVID-19: The Case for a Moratorium on Prescriptions.
Andreea Molnar, Stephanie Lau, Maja Berges, Raymond B Masa, Joshua J Solano, David L DeMets

Ther Innov Regul Sci· May 2022

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The challenges of data safety monitoring for a pragmatic study: Lessons from the ADAPTABLE study.
Zhen Huang, Frank W Rockhold, W Schuyler Jones, Adrian F Hernandez, Debbe McCall, David L DeMets

Contemp Clin Trials· April 2022

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Baseline Characteristics of Patients With HF With Mildly Reduced and Preserved Ejection Fraction: DELIVER Trial.
Scott D Solomon, Muthiah Vaduganathan, Brian L Claggett, Rudolf A de Boer, David DeMets

JACC Heart Fail· March 2022

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Data monitoring committee interim reports: We must get there soon!
David L DeMets, Janet Wittes

Clin Trials· February 2022

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Dapagliflozin and new-onset type 2 diabetes in patients with chronic kidney disease or heart failure: pooled analysis of the DAPA-CKD and DAPA-HF trials.
Peter Rossing, Silvio E Inzucchi, Priya Vart, Niels Jongs, Kieran F Docherty, David L DeMets

Lancet Diabetes Endocrinol· January 2022

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Primary care providers should prescribe aspirin to prevent cardiovascular disease based on benefit-risk ratio, not age.
Kyungmann Kim, Charles H Hennekens, Lisa Martinez, J Michael Gaziano, Marc A Pfeffer, David L DeMets

Fam Med Community Health· December 2021

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Monitoring clinical trials in infectious diseases.
David L DeMets, Thomas R Fleming, Susan S Ellenberg

J Allergy Infect Dis· January 2021

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