Publications by authors named "David N Hauser"

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Dopamine: Functions, Signaling, and Association with Neurological Diseases.
Marianne O Klein, Daniella S Battagello, Ariel R Cardoso, David N Hauser, Jackson C Bittencourt, Ricardo G Correa

Cell Mol Neurobiol· January 2019

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Longitudinal Characterization of Transcriptomic, Functional, and Morphological Features in Human iPSC-Derived Neurons and Their Application to Investigate Translational Progranulin Disease Biology.
Gaëlle Robin, J Corey Evans, David N Hauser, Paul Wren, Andreas Zembrzycki

Front Aging Neurosci· November 2020

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Differences in Stability, Activity and Mutation Effects Between Human and Mouse Leucine-Rich Repeat Kinase 2.
Rebekah G Langston, Iakov N Rudenko, Ravindran Kumaran, David N Hauser, Alice Kaganovich

Neurochem Res· June 2019

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Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice.
Laura Pellegrini, David N Hauser, Yan Li, Adamantios Mamais, Alexandra Beilina

Hum Mol Genet· September 2018

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The Effects of Variants in the Parkin, PINK1, and DJ-1 Genes along with Evidence for their Pathogenicity.
David N Hauser, Christopher T Primiani, Mark R Cookson

Curr Protein Pept Sci· November 2017

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Hexokinases link DJ-1 to the PINK1/parkin pathway.
David N Hauser, Adamantios Mamais, Melissa M Conti, Christopher T Primiani, Ravindran Kumaran

Mol Neurodegener· September 2017

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The Polg Mutator Phenotype Does Not Cause Dopaminergic Neurodegeneration in DJ-1-Deficient Mice.
David N Hauser, Christopher T Primiani, Rebekah G Langston, Ravindran Kumaran, Mark R Cookson

eNeuro· October 2015

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Post-translational decrease in respiratory chain proteins in the Polg mutator mouse brain.
David N Hauser, Allissa A Dillman, Jinhui Ding, Yan Li, Mark R Cookson

PLoS One· June 2015

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Use of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimers.
Janani Prahlad, David N Hauser, Nicole M Milkovic, Mark R Cookson, Mark A Wilson

J Neurochem· September 2014

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Arsenite stress down-regulates phosphorylation and 14-3-3 binding of leucine-rich repeat kinase 2 (LRRK2), promoting self-association and cellular redistribution.
Adamantios Mamais, Ruth Chia, Alexandra Beilina, David N Hauser, Christine Hall

J Biol Chem· August 2014

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Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.
Alexandria Beilina, Iakov N Rudenko, Alice Kaganovich, Laura Civiero, Hien Chau, David N Hauser

Proc Natl Acad Sci U S A· February 2014

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Dopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4.
David N Hauser, April A Dukes, Amanda D Mortimer, Teresa G Hastings

Free Radic Biol Med· December 2013

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mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex.
Allissa A Dillman, David N Hauser, J Raphael Gibbs, Michael A Nalls, Melissa K McCoy

Nat Neurosci· April 2013

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Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism.
David N Hauser, Teresa G Hastings

Neurobiol Dis· March 2013

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The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation.
Iakov N Rudenko, Alice Kaganovich, David N Hauser, Aleksandra Beylina, Ruth Chia

Biochem J· August 2012

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Astrocytes in Parkinson's disease and DJ-1.
David N Hauser, Mark R Cookson

J Neurochem· May 2011

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p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both.
Derek Narendra, Lesley A Kane, David N Hauser, Ian M Fearnley, Richard J Youle

Autophagy· November 2010

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