Publications by authors named "David P. Fairlie"

Claim this Profile
G
Genome of venomous caterpillar reveals recruitment of immune peptides and their adaptation as pain-inducing toxins.
Mohaddeseh H Goudarzi, Samuel D Robinson, Fernanda C Cardoso, Kushal Suryamohan, Nicole Lawrence, David P Fairlie

Proc Natl Acad Sci U S A· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Macrophage MR1 antigen presentation promotes MAIT cell immunity and lung microbiota modulation.
Jieru Deng, Yuting Yan, Xiaoyue Zhang, Calum J Walsh, Emmanuel Montassier, David P Fairlie

Science· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Restoration of MAIT cell function in healthcare-associated bacterial infections supports recovery of carbapenem efficacy against resistant bacteria.
Xue Yiting, Asad Mustafa Karim, Wan Rong Sia, Fei Han, Kai Lin Chan, David P Fairlie

bioRxiv· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Histone deacetylase 7 mediates lipopolysaccharide-inducible mitochondrial fission in macrophages.
Rishika Abrol, Syeda Farhana Afroz, James E B Curson, Karoline D Raven, Kaustav Das Gupta, David P Fairlie

J Cell Sci· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A molecular basis underpinning TRBV28 T-cell receptor recognition of MR1-antigen.
Wael Awad, Nicholas A Gherardin, Lisa Ciacchi, Andrew N Keller, Ligong Liu, David P Fairlie

J Biol Chem· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pro-ferroptotic lipids as key control points for caveola formation and disassembly.
Yeping Wu, Ye-Wheen Lim, Kerrie-Ann McMahon, Nick Martel, James Rae, David P Fairlie

Cell Rep· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Herpes simplex virus type 1 impairs mucosal-associated invariant T cells.
Lauren Stern, Zoe Emanuel, Renee Traves, Katherine Willis, Shivam K Purohit, David P Fairlie

mBio· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cigarette smoke components modulate the MR1-MAIT axis.
Wael Awad, Jemma R Mayall, Weijun Xu, Matt D Johansen, Timothy Patton, David P Fairlie

J Exp Med· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Human MAIT cell response profiles biased toward IL-17 or IL-10 are distinct effector states directed by the cytokine milieu.
Caroline Boulouis, Elli Mouchtaridi, Thomas R Müller, Jeffrey Y W Mak, David P Fairlie

Proc Natl Acad Sci U S A· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Protease-activated receptor 2: A promising therapeutic target for women's cancers.
Himani Shah, David P Fairlie, Junxian Lim

J Pharmacol Exp Ther· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel inhibitor of class IIa histone deacetylases attenuates collagen-induced arthritis.
Eunice K Poon, Ligong Liu, Kai-Chen Wu, Junxian Lim, Matthew J Sweet, David P Fairlie

Br J Pharmacol· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Selective regulation of IFN-γ and IL-4 co-producing unconventional T cells by purinergic signaling.
Calvin Xu, Andreas Obers, Minyi Qin, Alice Brandli, Joelyn Wong, David P Fairlie

J Exp Med· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MR1 presents vitamin B6-related compounds for recognition by MR1-reactive T cells.
Mitchell P McInerney, Wael Awad, Michael N T Souter, Yang Kang, Carl J H Wang, David P Fairlie

Proc Natl Acad Sci U S A· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MAIT cell plasticity enables functional adaptation that drives antibacterial immune protection.
Huimeng Wang, Michael N T Souter, Marcela de Lima Moreira, Shihan Li, Yuchen Zhou, David P Fairlie

Sci Immunol· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain.
Yizhuo Wang, James E B Curson, Divya Ramnath, Kaustav Das Gupta, Robert C Reid, David P Fairlie

Biochem J· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles.
Tobias Kammann, Curtis Cai, Takuya Sekine, Elli Mouchtaridi, Caroline Boulouis, David P Fairlie

Sci Immunol· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Varicella Zoster Virus disrupts MAIT cell polyfunctional effector responses.
Shivam K Purohit, Lauren Stern, Alexandra J Corbett, Jeffrey Y W Mak, David P Fairlie

PLoS Pathog· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis.
Jeffrey Y W Mak, Ryan J D Rivero, Huy N Hoang, Xin Yi Lim, Jieru Deng, David P Fairlie

Angew Chem Int Ed Engl· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MAIT cell-MR1 reactivity is highly conserved across multiple divergent species.
Matthew D Edmans, Timothy K Connelley, Sophie Morgan, Troi J Pediongco, Siddharth Jayaraman, David P Fairlie

J Biol Chem· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MAIT cell activation and recruitment in inflammation and tissue damage in acute appendicitis.
Yichao Zheng, Fei Han, Zhengyu Wu, Bingjie Wang, Xingchi Chen, David P Fairlie

Sci Adv· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PAR2 activation on human tubular epithelial cells engages converging signaling pathways to induce an inflammatory and fibrotic milieu.
David A Vesey, Abishek Iyer, Evan Owen, Danielle Kamato, David W Johnson, David P Fairlie

Front Pharmacol· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mouse mucosal-associated invariant T cell receptor recognition of MR1 presenting the vitamin B metabolite, 5-(2-oxopropylideneamino)-6-d-ribitylaminouracil.
Lisa Ciacchi, Jeffrey Y W Mak, Jeremy P Le, David P Fairlie, James McCluskey

J Biol Chem· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
W
Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm.
Zhixuan Wu, Sophie Shen, Dalia Mizikovsky, Yuanzhao Cao, Marina Naval-Sanchez, David P Fairlie

Dev Cell· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies.
Tobias Kammann, Jean-Baptiste Gorin, Tiphaine Parrot, Yu Gao, Andrea Ponzetta, David P Fairlie

J Immunol· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sulfated bile acid is a host-derived ligand for MAIT cells.
Emi Ito, Shinsuke Inuki, Yoshihiro Izumi, Masatomo Takahashi, Yuki Dambayashi, David P Fairlie

Sci Immunol· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis