Publications by authors named "David U"

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Integrating mutation, copy number, and gene expression data to identify driver genes of recurrent chromosome-arm losses.
Ron Saad, Ron Shamir, Uri Ben-David

Cell Rep· November 2025

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DeepTarget predicts anti-cancer mechanisms of action of small molecules by integrating drug and genetic screens.
Sanju Sinha, Neelam Sinha, Marlenne Perales, Adi Tarrab, Trinh Nguyen

NPJ Precis Oncol· November 2025

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Quantity of fat consumed predisposes cardiac tissues to greater metabolic risk than their level of saturation.
Ubong Edem David, Esther Oluwasola Aluko, Abodunrin Adebayo Ojetola, Adesoji Adedipe Fasanmade

Sci Rep· October 2025

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A single-center experience on endoscopic assisted evacuation of chronic subdural hematoma: is there a role for endoscopic evacuation in the modern era?
Netanel Ben-Shalom, Marcio Yuri Ferreira, James Feghali, Alon Orlev, Idan Levitan

Neurosurg Rev· September 2025

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Targeting vulnerabilities of aneuploid cells for cancer therapy.
Johanna Zerbib, Amit Bloomberg, Uri Ben-David

Trends Cancer· July 2025

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Evolutionary rescue by aneuploidy in tumors exposed to anticancer drugs.
Remus Stana, Uri Ben-David, Daniel B Weissman, Yoav Ram

Genetics· July 2025

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Neonatal seizures in Uyo: the burden, etiological factors and outcome.
Eno Etim Nyong, Mkpouto Udeme Akpan, Kingsley Irelosen Akhimienho, Ifunanya Ularinma Ebiekpi, Utibe David David

BMC Pediatr· June 2025

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CCL2 blockade combined with PD-1/P-selectin immunomodulators impedes breast cancer brain metastasis.
Sahar Israeli Dangoor, Rami Khoury, Koren Salomon, Sabina Pozzi, Shir Shahar

Brain· May 2025

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Cell and nuclear size are associated with chromosomal instability and tumorigenicity in cancer cells that undergo whole genome doubling.
Mathew Bloomfield, Sydney Huth, Daniella McCausland, Ron Saad, Nazia Bano

bioRxiv· April 2025

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High CDC20 levels increase sensitivity of cancer cells to MPS1 inhibitors.
Siqi Zheng, Linoy Raz, Lin Zhou, Yael Cohen-Sharir, Ruifang Tian

EMBO Rep· February 2025

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The cGAS-STING, p38 MAPK, and p53 pathways link genome instability to accelerated cellular senescence in ATM-deficient murine lung fibroblasts.
Majd Haj, Yann Frey, Amit Levon, Avishai Maliah, Tal Ben-Yishay

Proc Natl Acad Sci U S A· January 2025

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A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer.
Veronica Rendo, Michael Schubert, Nicholas Khuu, Maria F Suarez Peredo Rodriguez, Declan Whyte

Nat Commun· January 2025

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Increased RNA and Protein Degradation Is Required for Counteracting Transcriptional Burden and Proteotoxic Stress in Human Aneuploid Cells.
Marica Rosaria Ippolito, Johanna Zerbib, Yonatan Eliezer, Eli Reuveni, Sonia Viganò

Cancer Discov· December 2024

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The Antihypertensive Potential of Aqueous extract of (L.) Merr. is Up-regulation of Cyclic Guanosine Monophosphate and Down-regulation of the Renin-angiotensin System.
Esther Oluwasola Aluko, Ubong Edem David, Abodunrin Adebayo Ojetola, Adesoji Adedipe Fasanmade

Cardiovasc Hematol Disord Drug Targets· November 2024

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Chromosome 7 Gain Compensates for Chromosome 10 Loss in Glioma.
Nishanth Ulhas Nair, Alejandro A Schäffer, E Michael Gertz, Kuoyuan Cheng, Johanna Zerbib

Cancer Res· October 2024

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Aneuploidy as a driver of human cancer.
Eran Sdeor, Hajime Okada, Ron Saad, Tal Ben-Yishay, Uri Ben-David

Nat Genet· October 2024

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Aqueous extract of Peristrophe bivalvis (L.) Merr. leaf reversed the detrimental effects of nitric oxide synthase inhibitor on blood lipid profile and glucose level.
Esther Oluwasola Aluko, Ubong Edem David, Abodunrin Adebayo Ojetola, Adesoji Adedipe Fasanmade

PLoS One· September 2024

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Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage.
Johanna Zerbib, Marica Rosaria Ippolito, Yonatan Eliezer, Giuseppina De Feudis, Eli Reuveni

Nat Commun· September 2024

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Feeder-free culture of human pluripotent stem cells drives MDM4-mediated gain of chromosome 1q.
Dylan Stavish, Christopher J Price, Gabriele Gelezauskaite, Haneen Alsehli, Kimberly A Leonhard

Stem Cell Reports· August 2024

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A p62-dependent rheostat dictates micronuclei catastrophe and chromosome rearrangements.
Sara Martin, Simone Scorzoni, Sara Cordone, Alice Mazzagatti, Galina V Beznoussenko

Science· August 2024

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An Audit of Mortality Pattern in the Neonatology Unit of the University of Uyo Teaching Hospital, Uyo, Nigeria: A Seven-Year Review.
Enobong Edet Ekpenyong, Usenobong Morgan Akpan, Iso Precious Oloyede, Ifunanya Ularinma Ebiekpi, Utibe David David

Niger Med J· May 2024

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CKAP5 stabilizes CENP-E at kinetochores by regulating microtubule-chromosome attachments.
R Bhagya Lakshmi, Pinaki Nayak, Linoy Raz, Apurba Sarkar, Akshay Saroha

EMBO Rep· April 2024

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Machine-learning analysis reveals an important role for negative selection in shaping cancer aneuploidy landscapes.
Juman Jubran, Rachel Slutsky, Nir Rozenblum, Lior Rokach, Uri Ben-David

Genome Biol· April 2024

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Chromosome 7 to the rescue: overcoming chromosome 10 loss in gliomas.
Nishanth Ulhas Nair, Alejandro A Schäffer, E Michael Gertz, Kuoyuan Cheng, Johanna Zerbib

bioRxiv· January 2024

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Immunosignatures associated with TP53 status and co-mutations classify prognostically head and neck cancer patients.
Andrea Sacconi, Paola Muti, Claudio Pulito, Giulia Urbani, Matteo Allegretti

Mol Cancer· November 2023

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