Publications by authors named "Dean Betts"

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p66Shc silencing promotes aerobic glycolysis via signalling between the transcription factors NRF2 and HIF1-α.
Asad Lone, Reza Khazaee, Alexandra M Kozlov, Marc C J Courchesne, Karen Nygard, Dean H Betts

Free Radic Biol Med· December 2025

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Spatial heterogeneity of lactylation: Insights into gene expression, metabolism, and lactate transport in human embryonic stem cells.
Alexandra M Kozlov, Zuleika C L Leung, Rachel B Wilson, Sukhdeep Bhangal, Karen Nygard, Dean H Betts

Biol Open· December 2025

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p66Shc deletion confers apoptotic resistance to loss of EGFR-ERK signalling in neural stem cells.
Andrew M Powell, Robert C Cumming, Dean H Betts

Cell Death Dis· July 2025

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Elongation factor 1A1 regulates metabolic substrate preference in mammalian cells.
Rachel B Wilson, Alexandra M Kozlov, Helia Hatam Tehrani, Jessica S Twumasi-Ankrah, Yun Jin Chen, Dean H Betts

J Biol Chem· March 2024

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Deletion of Dysregulates ERK and STAT3 Activity in Mouse Embryonic Stem Cells, Enhancing Their Naive-Like Self-Renewal in the Presence of Leukemia Inhibitory Factor.
Andrew M Powell, Nicole A Edwards, Hailey Hunter, Patti Kiser, Andrew J Watson, Dean H Betts

Stem Cells Dev· August 2023

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Opening the "Black Box" Underlying Barriers to the Use of Canine Induced Pluripotent Stem Cells: A Narrative Review.
Alexander G Kuzma-Hunt, Vipra Shah, Sierra DiMarco, Keith A Russell, Dean H Betts

Stem Cells Dev· June 2023

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Selecting Normalizers for MicroRNA RT-qPCR Expression Analysis in Murine Preimplantation Embryos and the Associated Conditioned Culture Media.
David C Hawke, Andrew J Watson, Dean H Betts

J Dev Biol· April 2023

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Expression and localization of NRF2/Keap1 signalling pathway genes in mouse preimplantation embryos exposed to free fatty acids.
Grace Dionne, Michele Calder, Dean H Betts, Basim Abu Rafea, Andrew J Watson

Gene Expr Patterns· December 2022

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Evaluating Autophagy in Preimplantation Embryos.
Zuleika C L Leung, Hailey L M Hunter, Basim Abu Rafea, Andrew J Watson, Dean H Betts

Autophagy Rep· July 2022

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Modulation of PKM1/2 Levels by Steric Blocking Morpholinos Alters the Metabolic and Pluripotent State of Murine Pluripotent Stem Cells.
Joshua G Dierolf, Hailey L M Hunter, Andrew J Watson, Dean H Betts

Stem Cells Dev· June 2022

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Free fatty acid treatment of mouse preimplantation embryos demonstrates contrasting effects of palmitic acid and oleic acid on autophagy.
Zuleika C L Leung, Basim Abu Rafea, Andrew J Watson, Dean H Betts

Am J Physiol Cell Physiol· May 2022

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3D Immunofluorescent Image Colocalization Quantification in Mouse Epiblast Stem Cells.
Joshua G Dierolf, Andrew J Watson, Dean H Betts

Methods Mol Biol· May 2022

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Flow Cytometric Characterization of Pluripotent Cell Protein Markers in Naïve, Formative, and Primed Pluripotent Stem Cells.
Joshua G Dierolf, Kristin Chadwick, Courtney R Brooks, Andrew J Watson, Dean H Betts

Methods Mol Biol· May 2022

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Effects of palmitic acid on localization of embryo cell fate and blastocyst formation gene products.
Michele D Calder, Robert Chen, Anastasia MacDonald, Zoe MacNeily, Zuleika Chin Lai Leung, Dean H Betts

Reproduction· February 2022

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Cell Therapy in Veterinary Medicine as a Proof-of-Concept for Human Therapies: Perspectives From the North American Veterinary Regenerative Medicine Association.
Boaz Arzi, Tracy L Webb, Thomas G Koch, Susan W Volk, Dean H Betts

Front Vet Sci· November 2021

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Pannexin 1 binds β-catenin to modulate melanoma cell growth and metabolism.
Samar Sayedyahossein, Kenneth Huang, Zhigang Li, Christopher Zhang, Alexandra M Kozlov, Dean H Betts

J Biol Chem· August 2021

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Differential localization patterns of pyruvate kinase isoforms in murine naïve, formative, and primed pluripotent states.
Joshua G Dierolf, Andrew J Watson, Dean H Betts

Exp Cell Res· August 2021

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Murine Blastocysts Release Mature MicroRNAs Into Culture Media That Reflect Developmental Status.
David Connor Hawke, Danyal Baber Ahmed, Andrew John Watson, Dean Harvey Betts

Front Genet· May 2021

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Analysis of TERT Isoforms across TCGA, GTEx and CCLE Datasets.
Mathushan Subasri, Parisa Shooshtari, Andrew J Watson, Dean H Betts

Cancers (Basel)· April 2021

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Extracellular vesicles, microRNA and the preimplantation embryo: non-invasive clues of embryo well-being.
David Connor Hawke, Andrew John Watson, Dean Harvey Betts

Reprod Biomed Online· January 2021

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The use of induced pluripotent stem cells in domestic animals: a narrative review.
Rachel A Scarfone, Samantha M Pena, Keith A Russell, Dean H Betts, Thomas G Koch

BMC Vet Res· December 2020

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Targeted expression profiling reveals distinct stages of early canine fibroblast reprogramming are regulated by 2-oxoglutarate hydroxylases.
Ian C Tobias, Mian-Mian C Kao, Thomas Parmentier, Hailey Hunter, Jonathan LaMarre, Dean H Betts

Stem Cell Res Ther· December 2020

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Oleic Acid Counters Impaired Blastocyst Development Induced by Palmitic Acid During Mouse Preimplantation Development: Understanding Obesity-Related Declines in Fertility.
Maisoon D Yousif, Michele D Calder, Jin Tong Du, Kelsey N Ruetz, Kylie Crocker, Dean H Betts

Reprod Sci· November 2020

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Lactate preconditioning promotes a HIF-1α-mediated metabolic shift from OXPHOS to glycolysis in normal human diploid fibroblasts.
Alexandra M Kozlov, Asad Lone, Dean H Betts, Robert C Cumming

Sci Rep· May 2020

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Dynamic regulation of connexins in stem cell pluripotency.
Jessica L Esseltine, Courtney R Brooks, Nicole A Edwards, Mathushan Subasri, Jacinda Sampson, Dean H Betts

Stem Cells· January 2020

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