Publications by authors named "Derek McKay"

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In silico integrative scRNA analysis of human colonic epithelium indicates four tuft cell subtypes.
Aydin I Herik, Sarthak Sinha, Rohit Arora, Caleb Small, Antoine Dufour, Derek M McKay

Am J Physiol Gastrointest Liver Physiol· February 2025

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Exploring the connection between erythrocyte membrane fatty acid composition and oxidative stress in patients undergoing the Crohn's disease Therapeutic Diet Intervention (CD-TDI).
Natasha Haskey, Clara Letef, James A Sousa, Munazza Yousuf, Lorian M Taylor, Derek M McKay

Therap Adv Gastroenterol· February 2025

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Calcitonin gene-related peptide promotes epithelial reparative and anticolitic functions of IL-4 educated human macrophages.
Blanca E Callejas, James A Sousa, Kyle L Flannigan, Arthur Wang, Eve Higgins, Derek M McKay

Am J Physiol Gastrointest Liver Physiol· January 2025

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GPx1 deficiency confers increased susceptibility to ferroptosis in macrophages from individuals with active Crohn's disease.
James A Sousa, Blanca E Callejas, Arthur Wang, Eve Higgins, Aydin Herik, Derek M McKay

Cell Death Dis· December 2024

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Selenium, Immunity, and Inflammatory Bowel Disease.
James A Sousa, Derek M McKay, Maitreyi Raman

Nutrients· October 2024

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Enteric tuft cells coordinate timely expulsion of the tapeworm Hymenolepis diminuta from the murine host by coordinating local but not systemic immunity.
Sruthi Rajeev, ShuHua Li, Aralia Leon-Coria, Arthur Wang, Lucas Kraemer, Derek M McKay

PLoS Pathog· July 2024

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Neuroimmunophysiology of the gastrointestinal tract.
Derek M McKay, Manon Defaye, Sruthi Rajeev, Wallace K MacNaughton, Yasmin Nasser

Am J Physiol Gastrointest Liver Physiol· June 2024

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Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium.
Ravi Holani, Chathurika Rathnayaka, Graham A D Blyth, Anshu Babbar, Priyoshi Lahiri, Derek M McKay

J Innate Immun· December 2023

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Butyrate reduces adherent-invasive -evoked disruption of epithelial mitochondrial morphology and barrier function: involvement of free fatty acid receptor 3.
Samira A Hamed, Armaan Mohan, Saranya Navaneetha Krishnan, Arthur Wang, Marija Drikic, Derek M McKay

Gut Microbes· December 2023

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Tissue imaging reveals disruption of epithelial mitochondrial networks and loss of mitochondria-associated cytochrome-C in inflamed human and murine colon.
Andrew K Chojnacki, Saranya Navaneetha Krishnan, Humberto Jijon, Timothy E Shutt, Pina Colarusso, Derek M McKay

Mitochondrion· January 2023

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Macrophage immunotherapy: overcoming impediments to realize promise.
Laura M Sly, Derek M McKay

Trends Immunol· December 2022

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Hymenolepis diminuta.
Sruthi Rajeev, ShuHua Li, Derek M McKay

Trends Parasitol· November 2022

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Chemokines and chemokine receptors: Insights from human disease and experimental models of helminthiasis.
Lucas Kraemer, Derek M McKay, Remo Castro Russo, Ricardo Toshio Fujiwara

Cytokine Growth Factor Rev· August 2022

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Advances in the Immunobiology of Parasitic Diseases.
Jorge Morales-Montor, Derek M McKay, Luis I Terrazas

Pathogens· July 2022

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Impact of experimental colitis on mitochondrial bioenergetics in intestinal epithelial cells.
Luke Goudie, Nicole L Mancini, Timothy E Shutt, Graham P Holloway, Chunlong Mu, Derek M McKay

Sci Rep· May 2022

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Crohn's disease therapeutic dietary intervention (CD-TDI): study protocol for a randomised controlled trial.
Maitreyi Raman, Christopher Ma, Lorian M Taylor, Levinus A Dieleman, Georgios V Gkoutos, Derek M McKay

BMJ Open Gastroenterol· January 2022

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Crohn's Disease Pathobiont Adherent-Invasive E coli Disrupts Epithelial Mitochondrial Networks With Implications for Gut Permeability.
Nicole L Mancini, Sruthi Rajeev, Timothy S Jayme, Arthur Wang, Åsa V Keita, Derek M McKay

Cell Mol Gastroenterol Hepatol· December 2021

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Interleukin-4 Programmed Macrophages Suppress Colitis and Do Not Enhance Infectious-Colitis, Inflammation-Associated Colon Cancer or Airway Hypersensitivity.
Blanca E Callejas, Graham A D Blyth, Nicholas Jendzjowsky, Arthur Wang, Anshu Babbar, Derek M McKay

Front Immunol· December 2021

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Cooperation between host immunity and the gut bacteria is essential for helminth-evoked suppression of colitis.
Adam Shute, Blanca E Callejas, ShuHua Li, Arthur Wang, Timothy S Jayme, Derek M McKay

Microbiome· September 2021

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Enteric Tuft Cells in Host-Parasite Interactions.
Sruthi Rajeev, Olivia Sosnowski, Shuhua Li, Thibault Allain, André G Buret, Derek M McKay

Pathogens· September 2021

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Infection with Blocks Colitis and Hastens Recovery While Colitis Has Minimal Impact on Expulsion of the Cestode from the Mouse Host.
Shuhua Li, Sruthi Rajeev, Arthur Wang, Derek M McKay

Pathogens· August 2021

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Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation.
Jean-Paul Motta, Corinne Rolland, Anissa Edir, Ana-Carolina Florence, David Sagnat, Derek M McKay

Mucosal Immunol· May 2021

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Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production.
Ravi Holani, Anshu Babbar, Graham A D Blyth, Fernando Lopes, Humberto Jijon, Derek M McKay

Gut Microbes· November 2020

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Acceptance of the 2020 Clark P. Read Mentor Award: Prioritize Open Bidirectional Communication.
Derek M McKay

J Parasitol· November 2020

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Brain TNF drives post-inflammation depression-like behavior and persistent pain in experimental arthritis.
Fernando Lopes, Fernando A Vicentini, Nina L Cluny, Alexander J Mathews, Benjamin H Lee, Derek M McKay

Brain Behav Immun· October 2020

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