Publications by authors named "Doug Frantz"

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Pharmacokinetic and Biodistribution Studies of [F]-Taccalonolide: A Covalent Microtubule Stabilizer with Antitumor Efficacy.
Luke N Jaskowski, Nicholas A Clanton, Nancy J Wilkinson, Jennifer L Bartels, Peter M LoCoco, Amber N Frantz, Doug E Frantz

ACS Med Chem Lett· August 2025

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Ni-Catalyzed Cyanation of (Hetero)Aryl Electrophiles Using the Nontoxic Cyanating Reagent K[Fe(CN)].
Nicolas A Wilson, William M Palmer, Meredith K Slimp, Eric M Simmons, Matthew V Joannou, Doug E Frantz

ACS Catal· April 2025

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Site-Selective Functionalization of Unactivated Allylic C-H Bonds via Direct Deprotonation with KTMP: Application to the Formal Total Synthesis of (+)-Artemisinin from Amorphadiene.
Nicholas A Clanton, Nicolas A Wilson, Eliezer Ortiz, Shawn T Blumberg, Doug E Frantz

Org Lett· January 2023

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Pd-Catalyzed Chemoselective O‑Benzylation of Ambident 2‑Quinolinone Nucleophiles.
Melissa Cadena, Roberto Silva Villatoro, Jyoti Shah Gupta, Cody Phillips, Jonathan B Allen, Doug E Frantz

ACS Catal· August 2022

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Author Correction: Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs.
Jay W Schneider, Saji Oommen, Muhammad Y Qureshi, Sean C Goetsch, David R Pease, Doug E Frantz

Nat Med· July 2021

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A Metal-Free Reductive N-Alkylation of Indoles with Aldehydes.
Nicholas A Clanton, Taylor E Spiller, Eliezer Ortiz, Zhinong Gao, Juan Manuel Rodriguez-Poirier, Doug E Frantz

Org Lett· May 2021

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Synthesis and Biological Evaluations of Electrophilic Steroids Inspired by the Taccalonolides.
Nicholas A Clanton, Shayne D Hastings, Griffin B Foultz, Julie A Contreras, Samantha S Yee, Doug E Frantz

ACS Med Chem Lett· December 2020

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Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs.
Jay W Schneider, Saji Oommen, Muhammad Y Qureshi, Sean C Goetsch, David R Pease, Doug E Frantz

Nat Med· November 2020

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Pd- and Ni-Based Systems for the Catalytic Borylation of Aryl (Pseudo)halides with B(OH).
Charissa Munteanu, Taylor E Spiller, Jun Qiu, Albert J DelMonte, Steven R Wisniewski, Doug E Frantz

J Org Chem· August 2020

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An Electrophilic Natural Product Provides a Safe and Robust Odor Neutralization Approach To Counteract Malodorous Organosulfur Metabolites Encountered in Skunk Spray.
Lin Du, Charissa Munteanu, Jarrod B King, Doug E Frantz, Robert H Cichewicz

J Nat Prod· July 2019

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Direct Lewis Acid Catalyzed Conversion of Enantioenriched N-Acyloxazolidinones to Chiral Esters, Amides, and Acids.
Jason M Stevens, Ana Cristina Parra-Rivera, Darryl D Dixon, Gregory L Beutner, Albert J DelMonte, Doug E Frantz

J Org Chem· December 2018

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Cationic Alkynyl Heck Reaction toward Substituted Allenes Using BobCat: A New Hybrid Pd(0)-Catalyst Incorporating a Water-Soluble dba Ligand.
Robynne K Neff, Doug E Frantz

J Am Chem Soc· December 2018

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Ru(II)-Catalyzed Synthesis of Substituted Furans and Their Conversion to Butenolides.
Marie El Arba, Sara E Dibrell, Frederick Meece, Doug E Frantz

Org Lett· September 2018

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Unified Approach to Substituted Allenoates via Pd-Catalyzed β-Hydride Elimination of (E)-Enol Triflates.
Marie El Arba, Sara E Dibrell, Ian T Crouch, Doug E Frantz

Org Lett· October 2017

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Palladium-Catalyzed Synthesis of Alkynes via a Tandem Decarboxylation/Elimination of (E)-Enol Triflates.
Charissa Munteanu, Doug E Frantz

Org Lett· August 2016

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Iron-Catalyzed Stereoselective Cross-Coupling Reactions of Stereodefined Enol Carbamates with Grignard Reagents.
Ana Cristina Parra Rivera, Raymond Still, Doug E Frantz

Angew Chem Int Ed Engl· June 2016

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Development of an ex vivo lymph node explant model for identification of novel molecules active against Leishmania major.
Alex G Peniche, Yaneth Osorio, Adam R Renslo, Doug E Frantz, Peter C Melby

Antimicrob Agents Chemother· September 2014

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A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth.
Lei Wang, Jianjun Chang, Diana Varghese, Michael Dellinger, Subodh Kumar, Doug E Frantz

Nat Commun· December 2013

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Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites.
Claudia L L Valentim, Donato Cioli, Frédéric D Chevalier, Xiaohang Cao, Alexander B Taylor, Doug E Frantz

Science· December 2013

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The bat flower: a source of microtubule-destabilizing and -stabilizing compounds with synergistic antiproliferative actions.
April L Risinger, Jiangnan Peng, Cristina C Rohena, Hector R Aguilar, Doug E Frantz

J Nat Prod· October 2013

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Allosteric inhibition of hypoxia inducible factor-2 with small molecules.
Thomas H Scheuermann, Qiming Li, He-Wen Ma, Jason Key, Lei Zhang, Doug E Frantz

Nat Chem Biol· April 2013

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Pd-catalyzed asymmetric β-hydride elimination en route to chiral allenes.
Ian T Crouch, Robynne K Neff, Doug E Frantz

J Am Chem Soc· April 2013

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Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor.
Jamie L Rogers, Liela Bayeh, Thomas H Scheuermann, Jamie Longgood, Jason Key, Doug E Frantz

J Med Chem· February 2013

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Synchronized aromaticity as an enthalpic driving force for the aromatic Cope rearrangement.
David J Babinski, Xiaoguang Bao, Marie El Arba, Bo Chen, David A Hrovat, Doug E Frantz

J Am Chem Soc· October 2012

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Regulated expression of pH sensing G Protein-coupled receptor-68 identified through chemical biology defines a new drug target for ischemic heart disease.
Jamie L Russell, Sean C Goetsch, Hector R Aguilar, Helen Coe, Xiang Luo, Doug E Frantz

ACS Chem Biol· June 2012

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