Publications by authors named "Ellen Hoffman"

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Molecular and Genetic Mechanisms in Autism Spectrum Disorder.
April Pruitt, Abha R Gupta, Ellen J Hoffman

Ann Neurol· December 2025

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Dynamic convergence of neurodevelopmental disorder risk genes across neurodevelopment.
Meilin Fernandez Garcia, Kayla Retallick-Townsley, April Pruitt, Elizabeth Davidson, Novin Balafkan, Ellen J Hoffman

bioRxiv· July 2025

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Generation of stable brain cell cultures from embryonic zebrafish to interrogate phenotypes in zebrafish mutants of neurodevelopmental disorders.
G Lorenzo Odierna, Sarah Stednitz, April Pruitt, Joshua Arnold, Ellen J Hoffman

J Neurosci Methods· June 2025

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Review: Child Psychiatry in the Era of Genomics: The Promise of Translational Genetics Research for the Clinic.
Sarah E Fitzpatrick, Irene Antony, Erika L Nurmi, Thomas V Fernandez, Wendy K Chung, Ellen J Hoffman

JAACAP Open· June 2025

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A Blueprint for Translational Precision Medicine in Autism Spectrum Disorder and Related Neurogenetic Syndromes.
Robyn P Thom, Tracy L Warren, Suha Khan, Rebecca A Muhle, Paul P Wang, Ellen J Hoffman

J Child Adolesc Psychopharmacol· May 2025

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PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors.
Tyrone DeSpenza, Emre Kiziltug, Garrett Allington, Daniel G Barson, Stephen McGee, Ellen J Hoffman

Nat Neurosci· March 2025

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Brain-wide circuitry underlying altered auditory habituation in zebrafish models of autism.
Maya Wilde, Anahita Ghanbari, Tessa Mancienne, Ailís Moran, Rebecca E Poulsen, Ellen J Hoffman

bioRxiv· September 2024

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Pathogenic variants in autism gene cause hydrocephalus and disrupt neuronal connectivity by impairing ciliary microtubule dynamics.
Tyrone DeSpenza, Amrita Singh, Garrett Allington, Shujuan Zhao, Junghoon Lee, Ellen J Hoffman

Proc Natl Acad Sci U S A· July 2024

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Brain Registration and Evaluation for Zebrafish (BREEZE)-mapping: A pipeline for whole-brain structural and activity analyses.
David S Jin, Uma Neelakantan, Cheryl M Lacadie, Tianying Chen, Brendan Rooney, Ellen J Hoffman

STAR Protoc· December 2023

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Primary complex motor stereotypies are associated with de novo damaging DNA coding mutations that identify KDM5B as a risk gene.
Thomas V Fernandez, Zsanett P Williams, Tina Kline, Shreenath Rajendran, Farhan Augustine, Ellen J Hoffman

PLoS One· October 2023

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High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways.
Hellen Weinschutz Mendes, Uma Neelakantan, Yunqing Liu, Sarah E Fitzpatrick, Tianying Chen, Ellen J Hoffman

Cell Rep· March 2023

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PTEN mutations in autism spectrum disorder and congenital hydrocephalus: developmental pleiotropy and therapeutic targets.
Tyrone DeSpenza, Marina Carlson, Shreyas Panchagnula, Stephanie Robert, Phan Q Duy, Ellen J Hoffman

Trends Neurosci· December 2021

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Signaling Pathways and Sex Differential Processes in Autism Spectrum Disorder.
Kristen D Enriquez, Abha R Gupta, Ellen J Hoffman

Front Psychiatry· October 2021

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A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes.
François Kroll, Gareth T Powell, Marcus Ghosh, Gaia Gestri, Paride Antinucci, Ellen J Hoffman

Elife· January 2021

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Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus.
Sheng Chih Jin, Weilai Dong, Adam J Kundishora, Shreyas Panchagnula, Andres Moreno-De-Luca, Ellen J Hoffman

Nat Med· November 2020

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De Novo Damaging DNA Coding Mutations Are Associated With Obsessive-Compulsive Disorder and Overlap With Tourette's Disorder and Autism.
Carolina Cappi, Melody E Oliphant, Zsanett Péter, Gwyneth Zai, Maria Conceição do Rosário, Ellen J Hoffman

Biol Psychiatry· June 2020

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Zebrafish Models of Neurodevelopmental Disorders: Past, Present, and Future.
Catalina Sakai, Sundas Ijaz, Ellen J Hoffman

Front Mol Neurosci· August 2018

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Group-Based Compassion-Focused Therapy as an Adjunct to Outpatient Treatment for Eating Disorders: A Pilot Randomized Controlled Trial.
Allison Catherine Kelly, Lucene Wisniewski, Caitlin Martin-Wagar, Ellen Hoffman

Clin Psychol Psychother· March 2017

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Zebrafish: A Translational Model System for Studying Neuropsychiatric Disorders.
Sundas Ijaz, Ellen J Hoffman

J Am Acad Child Adolesc Psychiatry· September 2016

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Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2.
Ellen J Hoffman, Katherine J Turner, Joseph M Fernandez, Daniel Cifuentes, Marcus Ghosh

Neuron· February 2016

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Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism.
A Jeremy Willsey, Stephan J Sanders, Mingfeng Li, Shan Dong, Andrew T Tebbenkamp, Ellen J Hoffman

Cell· November 2013

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Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA).
Jeffry D Sander, Elizabeth J Dahlborg, Mathew J Goodwin, Lindsay Cade, Feng Zhang, Ellen Hoffman

Nat Methods· January 2011

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Progress in cytogenetics: implications for child psychopathology.
Ellen J Hoffman, Matthew W State

J Am Acad Child Adolesc Psychiatry· August 2010

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Indications for the use of diagnostic implantable and external ECG loop recorders.

Europace· May 2009

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A large-scale screen for coding variants in SERT/SLC6A4 in autism spectrum disorders.
Takeshi Sakurai, Jennifer Reichert, Ellen J Hoffman, Guiqing Cai, Hywel B Jones

Autism Res· August 2008

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