Publications by authors named "Eng Charis"

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Targeted RNA sequencing of thyroid tumors from individuals with PTEN hamartoma tumor syndrome reveals a unique transcriptome with a predominantly RAS-like expression profile.
Gilman Plitt, Takae Mitzukami, Lamis Yehia, Laura Rabinowitz, Christopher C Griffith, Charis Eng

Surgery· January 2026

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Sensitivity Analysis of the Efficacy of Everolimus for Neurocognitive Symptoms in PTEN Hamartoma Tumor Syndrome.
Yiran Liu, Runqiu Wang, Siddharth Srivastava, Booil Jo, Thomas Frazier, Charis Eng

Adv Ther· December 2025

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Altered Primary Somatosensory Neuron Development in a Pten Heterozygous Model for Autism Spectrum Disorder.
Alejandra Fernandez, Nick Sarn, Charis Eng, Kevin M Wright

Autism Res· November 2025

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Neurodevelopmental and Neurologic Manifestations of Hamartoma Tumor Syndrome: Management Recommendations.
Andrew Dhawan, Darren Liu, Sarah Baitamouni, Kristin Anthony, Siddharth Srivastava, Charis Eng

Neurol Genet· October 2025

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A structurally informed human protein-protein interactome reveals proteome-wide perturbations caused by disease mutations.
Dapeng Xiong, Yunguang Qiu, Junfei Zhao, Yadi Zhou, Dongjin Lee, Charis Eng

Nat Biotechnol· September 2025

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Elucidating PTEN conformational dynamics and phosphatase regulation via integrative modeling and mutation prediction.
Jennifer Erin Dawson, Iris Nira Smith, Ann Marie Tushar, Charis Eng

Structure· September 2025

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Which Score for What? Operationalizing Standardized Cognitive Test Performance for the Assessment of Change.
Cristan Farmer, Audrey Thurm, Tanvi Das, E Martina Bebin, Jonathan A Bernstein, Charis Eng

Am J Intellect Dev Disabil· September 2025

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Retraction: Phosphatase and Tensin Homologue Deleted on Chromosome 10 (PTEN) Has Nuclear Localization Signal-Like Sequences for Nuclear Import Mediated by Major Vault Protein.
Ji-Hyun Chung, Margaret E Ginn-Pease, Charis Eng

Cancer Res· September 2025

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Editor's Note: Nuclear-Cytoplasmic Partitioning of Phosphatase and Tensin Homologue Deleted on Chromosome 10 (PTEN) Differentially Regulates the Cell Cycle and Apoptosis.
Ji-Hyun Chung, Charis Eng

Cancer Res· September 2025

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The new microbiome on the block: challenges and opportunities of using human tumor sequencing data to study microbes.
Yingjie Li, Anjun Ma, Evan Johnson, Charis Eng, Subhajyoti De

Nat Methods· September 2025

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Neurobehavioral Signatures in Overgrowth Intellectual Disability Syndromes: Dissecting Genotype-Phenotype Relationships in the PI3K-AKT-MTOR Pathway.
Aaron D Besterman, Gerhard Hellemann, Irma Gutierrez-Mejia, Dzung C Nguyen, Joshua Sadik, Charis Eng

medRxiv· August 2025

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Cancer and Overgrowth Manifestations of PTEN Hamartoma Tumor Syndrome: Management Recommendations from the International PHTS Consensus Guidelines Working Group.
Andrew Dhawan, Sarah Baitamouni, Darren Liu, Lamis Yehia, Kristin Anthony, Charis Eng

Clin Cancer Res· May 2025

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Genotype-specific neoplastic risk profiles in patients with VHL disease.
Athina Ganner, Alfonso Massimiliano Ferrara, Peggy Sekula, Francesca Schiavi, Julia H Joo, Charis Eng

Endocr Relat Cancer· May 2025

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Genomic diversity in functionally relevant genes modifies neurodevelopmental versus neoplastic risks in individuals with germline PTEN variants.
Adriel Y Kim, Lamis Yehia, Charis Eng

NPJ Genom Med· May 2025

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Divergent PTEN-p53 interaction upon DNA damage in a human thyroid organoid model with germline PTEN mutations.
Juan Andres Venegas, Omer Enes Onur, Shin Chung Kang, Masahiro Hitomi, Charis Eng

Endocr Relat Cancer· April 2025

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Author Correction: The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer.
Jiacheng He, Xiaolei Chai, Qiansen Zhang, Yang Wang, Yijie Wang, Charis Eng

Nat Immunol· April 2025

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The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer.
Jiacheng He, Xiaolei Chai, Qiansen Zhang, Yang Wang, Yijie Wang, Charis Eng

Nat Immunol· March 2025

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Morphological and functional differences between hippocampal and cortical microglia and its impact on neuronal over-excitation in a germline Pten mutant mouse model.
Zhibing Tan, Parker L Bussies, Nicholas B Sarn, Muhammad Irfan, Tara DeSilva, Charis Eng

Neuroscience· March 2025

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Extended spectrum of cancers in PTEN hamartoma tumor syndrome.
Lamis Yehia, Gilman Plitt, Ann M Tushar, Darren Liu, Julia Joo, Charis Eng

NPJ Precis Oncol· March 2025

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Remote monitoring of social attention in neurogenetic syndromes and idiopathic neurodevelopmental disability.
Thomas W Frazier, Robyn M Busch, Patricia Klaas, Katherine Lachlan, Shafali Jeste, Charis Eng

Autism Res· February 2025

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Update on Pediatric Surveillance Recommendations for PTEN Hamartoma Tumor Syndrome, DICER1-Related Tumor Predisposition, and Tuberous Sclerosis Complex.
Kris Ann P Schultz, Suzanne P MacFarland, Melissa R Perrino, Sarah G Mitchell, Junne Kamihara, Charis Eng

Clin Cancer Res· January 2025

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The incidence of pancreatic cancer in women with a BRCA1 or BRCA2 mutation.
Bryson W Katona, Jan Lubinski, Tuya Pal, Tomasz Huzarski, William D Foulkes, Charis Eng

Cancer· January 2025

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Germline Genetic Susceptibility Testing Among Emirati Nationals at Risk for Hereditary Breast and Ovarian Cancer Syndrome.
Rifaat R Rawashdeh, Holly Pederson, Rafal Iskanderian, Fawad Khan, Basel Altrabulsi, Charis Eng

JCO Glob Oncol· November 2024

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Breast tumor microbiome regulates anti-tumor immunity and T cell-associated metabolites.
Chin-Chih Liu, Dennis Grencewicz, Karthik Chakravarthy, Lin Li, Ruth Liepold, Charis Eng

bioRxiv· November 2024

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