Publications by authors named "Eric D Brown"

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Uncovering the Hidden Antibiotic Potential of Cannabis.
Maya A Farha, Omar M El-Halfawy, Robert T Gale, Craig R MacNair, Lindsey A Carfrae, Xiong Zhang, Nicholas G Jentsch, Jakob Magolan, Eric D Brown

ACS Infect Dis· March 2020

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Author Correction: Discovery and artificial intelligence-guided mechanistic elucidation of a narrow-spectrum antibiotic.
Denise B Catacutan, Vian Tran, Autumn Arnold, Jeremie Alexander, Gabriele Corso, Eric D Brown

Nat Microbiol· December 2025

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Evaluation of Azithromycin-Bicarbonate against Multidrug-Resistant Pathogens in Topical Murine Models of Infection.
Maya A Farha, Megan M Tu, Lindsey Carfrae, Ashelyn E Sidders, Rodion Gordzevich, Eric D Brown

ACS Infect Dis· December 2025

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Discovery and artificial intelligence-guided mechanistic elucidation of a narrow-spectrum antibiotic.
Denise B Catacutan, Vian Tran, Autumn Arnold, Jeremie Alexander, Gabriele Corso, Eric D Brown

Nat Microbiol· November 2025

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Identifying Modulators of the Post-Antibiotic Effect.
Alexa L Gilberti, Megan M Tu, Kenneth Rachwalski, Madeeha I Ali, Siobhan A Cohen, Eric D Brown

ACS Infect Dis· September 2025

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Coniontins, lipopetaibiotics active against Candida auris identified from a microbial natural product fractionation library.
Xuefei Chen, Kalinka Koteva, Sommer Chou, Allison Guitor, Daniel Pallant, Eric D Brown

Nat Commun· August 2025

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Butyrolactol A potentiates caspofungin efficacy against resistant fungi via phospholipid flippase inhibition.
Xuefei Chen, H Diessel Duan, Michael J Hoy, Kalinka Koteva, Michaela Spitzer, Eric D Brown

bioRxiv· July 2025

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Host-like conditions validate nutrient transport as an antimalarial drug target.
Rodion Gordzevich, Eric D Brown

Cell Chem Biol· June 2025

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Cryo-EM analyses unveil details of mechanism and targocil-II mediated inhibition of S. aureus WTA transporter TarGH.
Franco K K Li, Shaun C Peters, Liam J Worrall, Tianjun Sun, Jinhong Hu, Eric D Brown

Nat Commun· April 2025

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Important challenges to finding new leads for new antibiotics.
Maya A Farha, Megan M Tu, Eric D Brown

Curr Opin Microbiol· February 2025

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Exploiting the fitness cost of metallo-β-lactamase expression can overcome antibiotic resistance in bacterial pathogens.
Megan M Tu, Lindsey A Carfrae, Kenneth Rachwalski, Shawn French, Denise Catacutan, Eric D Brown

Nat Microbiol· January 2025

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High-Throughput Discovery of Synthetic Siderophores for Trojan Horse Antibiotics.
Brent S Weber, Nikki E Ritchie, Simon Hilker, Derek C K Chan, Carsten Peukert, Eric D Brown

ACS Infect Dis· November 2024

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A screen for cell envelope stress uncovers an inhibitor of prolipoprotein diacylglyceryl transferase, Lgt, in .
Kenneth Rachwalski, Sean J Madden, Nicole Ritchie, Shawn French, Timsy Bhando, Eric D Brown

iScience· October 2024

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The inactivation of sensitizes to perturbations in lipopolysaccharide transport.
Shawna Zhu, Mary Kate Alexander, Telmo O Paiva, Kenneth Rachwalski, Anh Miu, Eric D Brown

iScience· May 2024

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A platform for predicting mechanism of action based on bacterial transcriptional responses identifies an unusual DNA gyrase inhibitor.
Shawn French, Amelia Bing Ya Guo, Michael J Ellis, Julia P Deisinger, Jarrod W Johnson, Eric D Brown

Cell Rep· April 2024

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Cryo-EM analysis of TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance.
Franco K K Li, Liam J Worrall, Robert T Gale, Eric D Brown, Natalie C J Strynadka

Sci Adv· March 2024

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A mobile CRISPRi collection enables genetic interaction studies for the essential genes of Escherichia coli.
Kenneth Rachwalski, Megan M Tu, Sean J Madden, Shawn French, Drew M Hansen, Eric D Brown

Cell Rep Methods· January 2024

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A standardized nomenclature for resistance-modifying agents in the Comprehensive Antibiotic Resistance Database.
Keaton W Smith, Brian P Alcock, Shawn French, Maya A Farha, Amogelang R Raphenya, Eric D Brown

Microbiol Spectr· December 2023

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Central metabolism is a key player in E. coli biofilm stimulation by sub-MIC antibiotics.
Luke N Yaeger, Shawn French, Eric D Brown, Jean Philippe Côté, Lori L Burrows

PLoS Genet· November 2023

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Screening under infection-relevant conditions reveals chemical sensitivity in multidrug resistant invasive non-typhoidal (iNTS).
Caressa N Tsai, Marie-Ange Massicotte, Craig R MacNair, Jordyn N Perry, Eric D Brown

RSC Chem Biol· August 2023

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Sociodemographic Differences in COVID-19 Pandemic Experiences Among Families in the United States.
Kaja Z LeWinn, Leonardo Trasande, Andrew Law, Courtney K Blackwell, Traci A Bekelman, Eric D Brown

JAMA Netw Open· August 2023

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Nutrient stress is a target for new antibiotics.
Lindsey A Carfrae, Eric D Brown

Trends Microbiol· June 2023

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Food for thought: Opportunities to target carbon metabolism in antibacterial drug discovery.
Madeline Tong, Eric D Brown

Ann N Y Acad Sci· June 2023

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Inhibiting fatty acid synthesis overcomes colistin resistance.
Lindsey A Carfrae, Kenneth Rachwalski, Shawn French, Rodion Gordzevich, Laura Seidel, Eric D Brown

Nat Microbiol· June 2023

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An Omniphobic Spray Coating Created from Hierarchical Structures Prevents the Contamination of High-Touch Surfaces with Pathogens.
Noor Abu Jarad, Kenneth Rachwalski, Fereshteh Bayat, Shadman Khan, Amid Shakeri, Eric D Brown

Small· March 2023

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A Bifunctional Spray Coating Reduces Contamination on Surfaces by Repelling and Killing Pathogens.
Noor Abu Jarad, Kenneth Rachwalski, Fereshteh Bayat, Shadman Khan, Amid Shakeri, Eric D Brown

ACS Appl Mater Interfaces· March 2023

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