Publications by authors named "Erwei Zuo"

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CRISPR/Cas9-mediated targeted chromosome elimination.
Erwei Zuo, Xiaona Huo, Xuan Yao, Xinde Hu, Yidi Sun, Jianhang Yin, Bingbing He, Xing Wang, Linyu Shi, Jie Ping

Genome Biol· November 2017

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AlphaCD: a machine learning model capable of highly accurate characterization for 21,335 cytidine deaminases.
Kui Xu, Guoying Hua, Mingdi Wu, Haihang Zhang, Jingda Liu, Erwei Zuo

Cell Res· October 2025

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SuperDecode: A versatile toolkit for mutation analysis in genome editing.
Guoying Hua, Chenfei He, Erwei Zuo

aBIOTECH· June 2025

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Developing a multi-modular assembled prime editing (mPE) system improved precise multi-base insertion efficiency in dicots.
Pengjun Lu, Erwei Zuo, Jianbin Yan

J Adv Res· May 2025

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Structure-guided discovery of highly efficient cytidine deaminases with sequence-context independence.
Kui Xu, Hu Feng, Haihang Zhang, Chenfei He, Huifang Kang, Zhenrui Zuo, Erwei Zuo

Nat Biomed Eng· January 2025

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Reducing off-target effects of DdCBEs by reversing amino acid charge near DNA interaction sites.
Long Xie, Yaqi Cao, Di Li, Mengxue Ma, Danrong Jiao, Zhenrui Zuo, Erwei Zuo

Cell Res· December 2024

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Overexpression of miRNA29a gene inhibits proliferation and promotes apoptosis of jejunal epithelial cells in yak.
Jianlei Jia, Erwei Zuo, Ning Li, Siyuan Kong, Pengjia Bao

Anim Biotechnol· November 2024

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A novel interpretable deep learning-based computational framework designed synthetic enhancers with broad cross-species activity.
Zhaohong Li, Yuanyuan Zhang, Bo Peng, Shenghua Qin, Qian Zhang, Erwei Zuo

Nucleic Acids Res· November 2024

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Adenine base editors induce off-target structure variations in mouse embryos and primary human T cells.
Leilei Wu, Shutan Jiang, Meisong Shi, Tanglong Yuan, Yaqin Li, Erwei Zuo

Genome Biol· November 2024

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Author Correction: Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation.
Guoling Li, Xue Dong, Jiamin Luo, Tanglong Yuan, Tong Li, Erwei Zuo

Nat Commun· October 2024

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Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation.
Guoling Li, Xue Dong, Jiamin Luo, Tanglong Yuan, Tong Li, Erwei Zuo

Nat Commun· September 2024

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Discovery of deaminase functions by structure-based protein clustering.
Jiaying Huang, Qiupeng Lin, Hongyuan Fei, Zixin He, Hu Xu, Erwei Zuo

Cell· August 2024

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Development of a universal antibiotic resistance screening system for efficient enrichment of C-to-G and A-to-G base editing.
Ying Xin, Hu Feng, Chenfei He, Hongjiang Lu, Erwei Zuo

Int J Biol Macromol· May 2024

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FokI-RYdCas9 Mediates Nearly PAM-Less and High-Precise Gene Editing in Human Cells.
Di Li, Yaqi Cao, Long Xie, Chenfei He, Danrong Jiao, Zhenrui Zuo, Erwei Zuo

Curr Issues Mol Biol· April 2024

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Chromosome-level genome of Ambrosia trifida provides insights into adaptation and the evolution of pollen allergens.
Lijuan Yin, Guangzhong Zhang, Chikai Zhou, Zhenghui Ou, Bo Qu, Erwei Zuo

Int J Biol Macromol· February 2024

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Deep learning models incorporating endogenous factors beyond DNA sequences improve the prediction accuracy of base editing outcomes.
Tanglong Yuan, Leilei Wu, Shiyan Li, Jitan Zheng, Nana Li, Zhenrui Zuo, Erwei Zuo

Cell Discov· February 2024

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Undetectable off-target effects induced by FokI catalytic domain in mouse embryos.
Long Xie, Hu Feng, Zhifang Li, Di Li, Xiali Yang, Zhenrui Zuo, Erwei Zuo

Genome Biol· February 2024

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THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development.
Jiali Zhang, Zhenzhou Jiang, Xueyuan Zhang, Ziqun Yang, Jinjiao Wang, Erwei Zuo

Nat Struct Mol Biol· January 2024

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An ovalbumin fusion strategy to increase recombinant protein secretion in chicken eggs.
Long Xie, Zhenwen Huang, Meiyu Lan, Yaqi Cao, Lingling Sun, Erwei Zuo

J Biol Eng· January 2024

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Genome-wide CRISPR off-target prediction and optimization using RNA-DNA interaction fingerprints.
Qinchang Chen, Guohui Chuai, Haihang Zhang, Jin Tang, Liwen Duan, Erwei Zuo

Nat Commun· November 2023

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Treatment of autosomal dominant retinitis pigmentosa caused by RHO-P23H mutation with high-fidelity Cas13X in mice.
Zixiang Yan, Yuqin Yao, Luyao Li, Lingqiong Cai, Haiwei Zhang, Erwei Zuo

Mol Ther Nucleic Acids· September 2023

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Discovery of deaminase functions by structure-based protein clustering.
Jiaying Huang, Qiupeng Lin, Hongyuan Fei, Zixin He, Hu Xu, Erwei Zuo

Cell· July 2023

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Human 8-cell embryos enable efficient induction of disease-preventive mutations without off-target effect by cytosine base editor.
Yinghui Wei, Meiling Zhang, Jing Hu, Yingsi Zhou, Mingxing Xue, Erwei Zuo

Protein Cell· June 2023

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Cytosine base editors induce off-target mutations and adverse phenotypic effects in transgenic mice.
Nana Yan, Hu Feng, Yongsen Sun, Ying Xin, Haihang Zhang, Zhenrui Zuo, Erwei Zuo

Nat Commun· March 2023

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Develop an efficient and specific AAV-based labeling system for Muller glia in mice.
Yanxia Gao, Kailun Fang, Zixiang Yan, Haiwei Zhang, Guannan Geng, Erwei Zuo

Sci Rep· December 2022

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: Predicting sgRNA activity for CRISPR-mediated epigenome editing by deep learning.
Qianqian Yang, Leilei Wu, Juan Meng, Lei Ma, Erwei Zuo

Comput Struct Biotechnol J· November 2022

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