Publications by authors named "George Witman"

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Activation of the ciliary kinase CDKL5 is mediated by the cyclin-dependent kinase CDK20/LF2 to control flagellar length.
Yuqing Hou, Oranti Ahmed Omi, Michael W Stuck, Xi Cheng, Bethany Walker, George B Witman

PLoS Biol· December 2025

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Distribution and bulk flow analyses of the intraflagellar transport (IFT) motor kinesin-2 support an "on-demand" model for Chlamydomonas ciliary length control.
Mansi B Patel, Paul J Griffin, Spencer F Olson, Jin Dai, Yuqing Hou, George B Witman

Cytoskeleton (Hoboken)· November 2024

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Direct in situ protein tagging in Chlamydomonas reinhardtii utilizing TIM, a method for CRISPR/Cas9-based targeted insertional mutagenesis.
Yuqing Hou, Xi Cheng, George B Witman

PLoS One· December 2022

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Consensus nomenclature for dyneins and associated assembly factors.
Bryony Braschi, Heymut Omran, George B Witman, Gregory J Pazour, K Kevin Pfister

J Cell Biol· February 2022

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Structural organization of the C1b projection within the ciliary central apparatus.
Kai Cai, Yanhe Zhao, Lei Zhao, Nhan Phan, Yuqing Hou, George B Witman

J Cell Sci· November 2021

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Chlamydomonas FAP70 is a component of the previously uncharacterized ciliary central apparatus projection C2a.
Yuqing Hou, Lei Zhao, Tomohiro Kubo, Xi Cheng, Nathan McNeill, George B Witman

J Cell Sci· June 2021

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Diffusion rather than intraflagellar transport likely provides most of the tubulin required for axonemal assembly in .
Julie Craft Van De Weghe, J Aaron Harris, Tomohiro Kubo, George B Witman, Karl F Lechtreck

J Cell Sci· September 2020

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TIM, a targeted insertional mutagenesis method utilizing CRISPR/Cas9 in Chlamydomonas reinhardtii.
Tyler Picariello, Yuqing Hou, Tomohiro Kubo, Nathan A McNeill, Haru-Aki Yanagisawa, George B Witman

PLoS One· July 2020

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The unity and diversity of the ciliary central apparatus.
Lei Zhao, Yuqing Hou, Nathan A McNeill, George B Witman

Philos Trans R Soc Lond B Biol Sci· February 2020

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Structural organization of the C1a-e-c supercomplex within the ciliary central apparatus.
Gang Fu, Lei Zhao, Erin Dymek, Yuqing Hou, Kangkang Song, George B Witman

J Cell Biol· December 2019

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Proteome of the central apparatus of a ciliary axoneme.
Lei Zhao, Yuqing Hou, Tyler Picariello, Branch Craige, George B Witman

J Cell Biol· June 2019

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A global analysis of IFT-A function reveals specialization for transport of membrane-associated proteins into cilia.
Tyler Picariello, Jason M Brown, Yuqing Hou, Gregory Swank, Deborah A Cochran, George B Witman

J Cell Sci· February 2019

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A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1).
Tomohiro Kubo, Yuqing Hou, Deborah A Cochran, George B Witman, Toshiyuki Oda

Mol Biol Cell· May 2018

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Characterization of a new oda3 allele, oda3-6, defective in assembly of the outer dynein arm-docking complex in Chlamydomonas reinhardtii.
Jason M Brown, Matthew Mosley, Daniela Montes-Berrueta, Yuqing Hou, Fan Yang, George B Witman

PLoS One· September 2017

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The N-terminus of IFT46 mediates intraflagellar transport of outer arm dynein and its cargo-adaptor ODA16.
Yuqing Hou, George B Witman

Mol Biol Cell· September 2017

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IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium.
Jenna L Wingfield, Ilaria Mengoni, Heather Bomberger, Yu-Yang Jiang, Jonathon D Walsh, George B Witman

Elife· May 2017

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Together, the IFT81 and IFT74 N-termini form the main module for intraflagellar transport of tubulin.
Tomohiro Kubo, Jason M Brown, Karl Bellve, Branch Craige, Julie M Craft, George B Witman

J Cell Sci· May 2016

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Corrigendum: TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport.
Miriam Schmidts, Yuqing Hou, Claudio R Cortés, Dorus A Mans, Celine Huber, George B Witman

Nat Commun· March 2016

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Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm.
Jovenal T San Agustin, Gregory J Pazour, George B Witman

Mol Biol Cell· December 2015

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CFAP54 is required for proper ciliary motility and assembly of the central pair apparatus in mice.
Casey W McKenzie, Branch Craige, Tiffany V Kroeger, Rozzy Finn, Todd A Wyatt, George B Witman

Mol Biol Cell· September 2015

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Superresolution Pattern Recognition Reveals the Architectural Map of the Ciliary Transition Zone.
T Tony Yang, Jimmy Su, Won-Jing Wang, Branch Craige, George B Witman

Sci Rep· September 2015

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DRC3 connects the N-DRC to dynein g to regulate flagellar waveform.
Junya Awata, Kangkang Song, Jianfeng Lin, Stephen M King, Michael J Sanderson, George B Witman

Mol Biol Cell· August 2015

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Reduced tubulin polyglutamylation suppresses flagellar shortness in Chlamydomonas.
Tomohiro Kubo, Masafumi Hirono, Takumi Aikawa, Ritsu Kamiya, George B Witman

Mol Biol Cell· August 2015

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TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport.
Miriam Schmidts, Yuqing Hou, Claudio R Cortés, Dorus A Mans, Celine Huber, George B Witman

Nat Commun· June 2015

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Assembly of IFT trains at the ciliary base depends on IFT74.
Jason M Brown, Deborah A Cochran, Branch Craige, Tomohiro Kubo, George B Witman

Curr Biol· June 2015

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