Publications by authors named "Gerald Hammond"

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Stereoselective Degradation of Diacylglycerol Kinases Potentiate T cell Activation and Tumor Cell Cytotoxicity.
Minhaj Shaikh, Surya Pravo Mookherjee, Claire C Weckerly, Adam H Libby, Aizhen Xiao, Gerald R V Hammond

bioRxiv· December 2025

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PILS-Nir1 is a sensitive phosphatidic acid biosensor that reveals mechanisms of lipid production.
Claire C Weckerly, Taylor A Rahn, Max Ehrlich, Rachel C Wills, Joshua G Pemberton, Gerald R V Hammond

J Cell Biol· November 2025

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Subcellular Cartography of the Phosphoinositide Multiverse.
Morgan M C Ricci, Claire C Weckerly, Gerald R V Hammond

Biochim Biophys Acta Mol Cell Biol Lipids· November 2025

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Quantitative comparison of PI(3,5)P biosensors reveals SnxA is the most sensitive and unbiased.
Tiernan Swayhoover, Claire C Weckerly, Gerald R V Hammond

bioRxiv· November 2025

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PIP4K attenuates PIP5K lipid kinase activity by disrupting membrane-mediated dimerization.
Benjamin R Duewell, Michael J Chirumbolo, Samantha M Fernandez-Ortiz, Gerald R V Hammond, Scott D Hansen

bioRxiv· September 2025

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PILS-Nir1 is a novel phosphatidic acid biosensor that reveals mechanisms of lipid production.
Claire C Weckerly, Taylor A Rahn, Max Ehrlich, Rachel C Wills, Joshua G Pemberton, Gerald R V Hammond

bioRxiv· July 2025

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MTMR regulates KRAS function by controlling plasma membrane levels of phospholipids.
Taylor E Lange, Ali Naji, Ransome van der Hoeven, Hong Liang, Yong Zhou, Gerald R V Hammond

J Cell Biol· July 2025

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Single-molecule lipid biosensors mitigate inhibition of endogenous effector proteins.
Victoria L Holmes, Morgan M C Ricci, Claire C Weckerly, Michael Worcester, Gerald R V Hammond

J Cell Biol· March 2025

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MTMR regulates KRAS function by controlling plasma membrane levels of phospholipids.
Taylor E Lange, Ali Naji, Ransome van der Hoeven, Hong Liang, Yong Zhou, Gerald R V Hammond

bioRxiv· February 2025

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Single molecule Lipid Biosensors Mitigate Inhibition of Endogenous Effector Proteins.
Victoria Holmes, Morgan M C Ricci, Claire C Weckerly, Michael Worcester, Gerald R V Hammond

bioRxiv· January 2025

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Fast-diffusing receptor collisions with slow-diffusing peptide ligand assemble the ternary parathyroid hormone-GPCR-arrestin complex.
Jonathan Pacheco, Karina A Peña, Sofya Savransky, Alexandre Gidon, Gerald R V Hammond

Nat Commun· December 2024

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Synthesis and Electrophilic Trifluoromethylthiolation Properties of 1-Methyl-4-(trifluoromethylthio)piperazine (MTTP).
Seyedesahar Miraghaee, Teruo Umemoto, Gerald B Hammond

Org Lett· August 2024

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Orthogonal Targeting of SAC1 to Mitochondria Implicates ORP2 as a Major Player in PM PI4P Turnover.
Colleen P Doyle, Andrew Rectenwald, Liz Timple, Gerald R V Hammond

Contact (Thousand Oaks)· February 2024

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OSBP is a Major Determinant of Golgi Phosphatidylinositol 4-Phosphate Homeostasis.
Colleen P Doyle, Liz Timple, Gerald R V Hammond

Contact (Thousand Oaks)· February 2024

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Orthogonal targeting of SAC1 to mitochondria implicates ORP2 as a major player in PM PI4P turnover.
Colleen P Doyle, Andrew Rectenwald, Liz Timple, Gerald R V Hammond

bioRxiv· January 2024

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Actin-binding protein profilin1 is an important determinant of cellular phosphoinositide control.
Morgan M C Ricci, Andrew Orenberg, Lee Ohayon, David Gau, Rachel C Wills, Gerald R V Hammond

J Biol Chem· January 2024

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OSBP is a major determinant of Golgi phosphatidylinositol 4-phosphate homeostasis.
Colleen P Doyle, Liz Timple, Gerald R V Hammond

bioRxiv· January 2024

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Molding a PI(3,5)P2 biosensor.
Claire C Weckerly, Gerald R V Hammond

J Cell Biol· September 2023

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Preparation and Reactivity Study of a Versatile Trifluoromethylthiolating Agent: S-Trifluoromethyl Trifluoromethanesulfonothioate (TTST).
Yuhao Yang, Seyedesahar Miraghaee, Renee Pace, Teruo Umemoto, Gerald B Hammond

Angew Chem Int Ed Engl· August 2023

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A novel homeostatic mechanism tunes PI(4,5)P2-dependent signaling at the plasma membrane.
Rachel C Wills, Colleen P Doyle, James P Zewe, Jonathan Pacheco, Scott D Hansen, Gerald R V Hammond

J Cell Sci· August 2023

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Beyond PI3Ks: targeting phosphoinositide kinases in disease.
John E Burke, Joanna Triscott, Brooke M Emerling, Gerald R V Hammond

Nat Rev Drug Discov· May 2023

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PI(4,5)P2 diffuses freely in the plasma membrane even within high-density effector protein complexes.
Jonathan Pacheco, Anna C Cassidy, James P Zewe, Rachel C Wills, Gerald R V Hammond

J Cell Biol· February 2023

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PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages.
Fernando Montaño-Rendón, Glenn F W Walpole, Matthias Krause, Gerald R V Hammond, Sergio Grinstein

J Cell Biol· November 2022

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PI(4,5)P2: signaling the plasma membrane.
Rachel C Wills, Gerald R V Hammond

Biochem J· November 2022

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Synthesis and applications of S-(trifluoromethyl)-2,8-bis(trifluoromethoxy)dibenzothiophenium triflate (Umemoto reagent IV).
Sagar R Mudshinge, Gerald B Hammond, Teruo Umemoto

J Fluor Chem· September 2022

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