Publications by authors named "Gerhard Hofle"

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Isolation, Structure Elucidation, and (Bio)Synthesis of Haprolid, a Cell-Type-Specific Myxobacterial Cytotoxin.
Heinrich Steinmetz, Jun Li, Chengzhang Fu, Nestor Zaburannyi, Birgitte Kunze

Angew Chem Int Ed Engl· August 2016

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Isolation, Structure Elucidation, Biosynthesis, and Synthesis of Antalid, a Secondary Metabolite from Polyangium species.
Thomas Tautz, Judith Hoffmann, Thomas Hoffmann, Heinrich Steinmetz, Peter Washausen

Org Lett· June 2016

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Characterizing the Epothilone Binding Site on β-Tubulin by Photoaffinity Labeling: Identification of β-Tubulin Peptides TARGSQQY and TSRGSQQY as Targets of an Epothilone Photoprobe for Polymerized Tubulin.
Adwait R Ranade, LeeAnn Higgins, Todd W Markowski, Nicole Glaser, Dmitry Kashin

J Med Chem· April 2016

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Isolation and structure elucidation of the nucleoside antibiotic strepturidin from Streptomyces albus DSM 40763.
Alexander Pesic, Britta Steinhaus, Sebastian Kemper, Jonny Nachtigall, Hans Jürgen Kutzner

J Antibiot (Tokyo)· June 2014

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Amethystin, the coloring principle of Stentor amethystinus.
Gerhard Höfle, Silke Reinecke, Uwe Laude, Dietrich Spitzner

J Nat Prod· June 2014

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Isolation, biological activity evaluation, structure elucidation, and total synthesis of eliamid: a novel complex I inhibitor.
Gerhard Höfle, Klaus Gerth, Hans Reichenbach, Brigitte Kunze, Florenz Sasse

Chemistry· September 2012

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Sulfangolids, macrolide sulfate esters from Sorangium cellulosum.
Wiebke Zander, Herbert Irschik, Hermann Augustiniak, Martina Herrmann, Rolf Jansen

Chemistry· May 2012

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Pellasoren: structure elucidation, biosynthesis, and total synthesis of a cytotoxic secondary metabolite from Sorangium cellulosum.
Christine Jahns, Thomas Hoffmann, Stefan Müller, Klaus Gerth, Peter Washausen

Angew Chem Int Ed Engl· May 2012

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Isolation and total synthesis of icumazoles and noricumazoles--antifungal antibiotics and cation-channel blockers from Sorangium cellulosum.
Jenny Barbier, Rolf Jansen, Herbert Irschik, Stefan Benson, Klaus Gerth

Angew Chem Int Ed Engl· January 2012

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Molecular basis of elansolid biosynthesis: evidence for an unprecedented quinone methide initiated intramolecular Diels-Alder cycloaddition/macrolactonization.
Richard Dehn, Yohei Katsuyama, Arne Weber, Klaus Gerth, Rolf Jansen

Angew Chem Int Ed Engl· April 2011

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Gephyronic acid, a missing link between polyketide inhibitors of eukaryotic protein synthesis (part I): Structural revision and stereochemical assignment of gephyronic acid.
Lionel Nicolas, Timo Anderl, Florenz Sasse, Heinrich Steinmetz, Rolf Jansen

Angew Chem Int Ed Engl· January 2011

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Gephyronic acid, a missing link between polyketide inhibitors of eukaryotic protein synthesis (part II): Total synthesis of gephyronic acid.
Timo Anderl, Lionel Nicolas, Johanna Münkemer, Angelika Baro, Florenz Sasse

Angew Chem Int Ed Engl· January 2011

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The epothilones: an outstanding family of anti-tumor agents. General aspects.
Gerhard Höfle

Fortschr Chem Org Naturst· June 2009

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Semisynthesis and antiplasmodial activity of the quinoline alkaloid aurachin E.
Gerhard Höfle, Bettina Bööhlendorf, Thomas Fecker, Florenz Sasse, Brigitte Kunze

J Nat Prod· November 2008

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Isolation and biosynthesis of aurachin P and 5-nitroresorcinol from Stigmatella erecta.
Gerhard Höfle, Herbert Irschik

J Nat Prod· November 2008

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Biosynthesis of aurachins A-L in Stigmatella aurantiaca: a feeding study.
Gerhard Höfle, Brigitte Kunze

J Nat Prod· November 2008

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Discovery and development of the epothilones : a novel class of antineoplastic drugs.
Hans Reichenbach, Gerhard Höfle

Drugs R D· May 2008

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Chlorotonil A, a macrolide with a unique gem-dichloro-1,3-dione functionality from Sorangium cellulosum, So ce1525.
Klaus Gerth, Heinrich Steinmetz, Gerhard Höfle, Rolf Jansen

Angew Chem Int Ed Engl· February 2008

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Pedein A and B: production, isolation, structure elucidation and biological properties of new antifungal cyclopeptides from Chondromyces pediculatus (Myxobacteria).
Brigitte Kunze, Bettina Böhlendorf, Hans Reichenbach, Gerhard Höfle

J Antibiot (Tokyo)· January 2008

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The thuggacins, novel antibacterial macrolides from Sorangium cellulosum acting against selected Gram-positive bacteria.
Herbert Irschik, Hans Reichenbach, Gerhard Höfle, Rolf Jansen

J Antibiot (Tokyo)· December 2007

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Thuggacins, macrolide antibiotics active against Mycobacterium tuberculosis: isolation from myxobacteria, structure elucidation, conformation analysis and biosynthesis.
Heinrich Steinmetz, Herbert Irschik, Brigitte Kunze, Hans Reichenbach, Gerhard Höfle

Chemistry· September 2007

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Side-chain truncation of apicularen A by olefin cross-metathesis with ethylene.
Larissa Jundt, Gerhard Höfle

J Nat Prod· August 2007

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Etnangien, a macrolide-polyene antibiotic from Sorangium cellulosum that inhibits nucleic acid polymerases.
Herbert Irschik, Dietmar Schummer, Gerhard Höfle, Hans Reichenbach, Heinrich Steinmetz

J Nat Prod· June 2007

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Microtubule stabilizer ameliorates synaptic function and behavior in a mouse model for schizophrenia.
Annie Andrieux, Paul Salin, Annie Schweitzer, Mélina Bégou, Bastien Pachoud

Biol Psychiatry· December 2006

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Cruentaren, a new antifungal salicylate-type macrolide from Byssovorax cruenta (myxobacteria) with inhibitory effect on mitochondrial ATPase activity. Fermentation and biological properties.
Brigitte Kunze, Heinrich Steinmetz, Gerhard Höfle, Markus Huss, Helmut Wieczorek

J Antibiot (Tokyo)· October 2006

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