Publications by authors named "Gregory Frolenkov"

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Author Correction: Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48.
Saima Riazuddin, Inna A Belyantseva, Arnaud P J Giese, Kwanghyuk Lee, Artur A Indzhykulian, Gregory I Frolenkov

Nat Genet· September 2025

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Lifelong dynamic maintenance of stereocilia bundles in mammalian auditory hair cells.
A Catalina Vélez-Ortega, Gregory I Frolenkov

Curr Top Dev Biol· September 2025

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Taperin bundles F-actin at stereocilia pivot points enabling optimal lifelong mechanosensitivity.
Inna A Belyantseva, Chang Liu, Abigail K Dragich, Takushi Miyoshi, Sayaka Inagaki, Gregory I Frolenkov

J Cell Biol· August 2025

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A Myosin Nanomotor Essential for Stereocilia Maintenance Expands the Etiology of Hereditary Hearing Loss DFNB3.
Ghazaleh Behnammanesh, Abigail K Dragich, Xiayi Liao, Shadan Hadi, Mi-Jung Kim, Gregory I Frolenkov

bioRxiv· February 2025

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Regulation of cochlear hair cell function by intracellular calcium stores.
Ghanshyam P Sinha, Gregory I Frolenkov

Front Cell Neurosci· November 2024

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Imaging analysis reveals budding of filamentous human metapneumovirus virions and direct transfer of inclusion bodies through intercellular extensions.
Farah El Najjar, Santiago Restrepo Castillo, Carole L Moncman, Cheng-Yu Wu, Eduardo Isla, Gregory I Frolenkov

mBio· October 2023

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Generating high-fidelity cochlear organoids from human pluripotent stem cells.
Stephen T Moore, Takashi Nakamura, Jing Nie, Alexander J Solivais, Isabel Aristizábal-Ramírez, Gregory I Frolenkov

Cell Stem Cell· July 2023

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Calcium and Integrin-binding protein 2 (CIB2) controls force sensitivity of the mechanotransducer channels in cochlear outer hair cells.
Isabel Aristizábal-Ramírez, Abigail K Dragich, Arnaud P J Giese, K Sofia Zuluaga-Osorio, Julie Watkins, Gregory I Frolenkov

bioRxiv· July 2023

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TRPA1 activation in non-sensory supporting cells contributes to regulation of cochlear sensitivity after acoustic trauma.
A Catalina Vélez-Ortega, Ruben Stepanyan, Stephanie E Edelmann, Sara Torres-Gallego, Channy Park, Gregory I Frolenkov

Nat Commun· June 2023

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Unbalanced bidirectional radial stiffness gradients within the organ of Corti promoted by TRIOBP.
Hesam Babahosseini, Inna A Belyantseva, Rizwan Yousaf, Risa Tona, Shadan Hadi, Gregory I Frolenkov

Proc Natl Acad Sci U S A· June 2022

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Modification of cell wall polysaccharide guides cell division in Streptococcus mutans.
Svetlana Zamakhaeva, Catherine T Chaton, Jeffrey S Rush, Sowmya Ajay Castro, Cameron W Kenner, Gregory I Frolenkov

Nat Chem Biol· August 2021

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Stereocilia Bundle Imaging with Nanoscale Resolution in Live Mammalian Auditory Hair Cells.
Carolina Galeano-Naranjo, A Catalina Veléz-Ortega, Gregory I Frolenkov

J Vis Exp· January 2021

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Myosins and Hearing.
Thomas B Friedman, Inna A Belyantseva, Gregory I Frolenkov

Adv Exp Med Biol· August 2020

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Myosin-XVa Controls Both Staircase Architecture and Diameter Gradation of Stereocilia Rows in the Auditory Hair Cell Bundles.
Shadan Hadi, Andrew J Alexander, A Catalina Vélez-Ortega, Gregory I Frolenkov

J Assoc Res Otolaryngol· April 2020

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TRIOBP-5 sculpts stereocilia rootlets and stiffens supporting cells enabling hearing.
Tatsuya Katsuno, Inna A Belyantseva, Alexander X Cartagena-Rivera, Keisuke Ohta, Shawn M Crump, Gregory I Frolenkov

JCI Insight· June 2019

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Building and repairing the stereocilia cytoskeleton in mammalian auditory hair cells.
A Catalina Vélez-Ortega, Gregory I Frolenkov

Hear Res· May 2019

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Helios is a key transcriptional regulator of outer hair cell maturation.
Lauren Chessum, Maggie S Matern, Michael C Kelly, Stuart L Johnson, Yoko Ogawa, Gregory I Frolenkov

Nature· November 2018

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Visualization of Live Cochlear Stereocilia at a Nanoscale Resolution Using Hopping Probe Ion Conductance Microscopy.
A Catalina Vélez-Ortega, Gregory I Frolenkov

Methods Mol Biol· December 2017

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CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.
Arnaud P J Giese, Yi-Quan Tang, Ghanshyam P Sinha, Michael R Bowl, Adam C Goldring, Gregory I Frolenkov

Nat Commun· June 2017

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Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells.
A Catalina Vélez-Ortega, Mary J Freeman, Artur A Indzhykulian, Jonathan M Grossheim, Gregory I Frolenkov

Elife· March 2017

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A Novel C-Terminal CIB2 (Calcium and Integrin Binding Protein 2) Mutation Associated with Non-Syndromic Hearing Loss in a Hispanic Family.
Kunjan Patel, Arnaud P Giese, J M Grossheim, Rashmi S Hegde, Maria Delio, Gregory I Frolenkov

PLoS One· June 2016

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Angular Approach Scanning Ion Conductance Microscopy.
Andrew Shevchuk, Sergiy Tokar, Sahana Gopal, Jose L Sanchez-Alonso, Andrei I Tarasov, Gregory I Frolenkov

Biophys J· May 2016

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Correction: A Novel C-Terminal CIB2 (Calcium and Integrin Binding Protein 2) Mutation Associated with Non-Syndromic Hearing Loss in a Hispanic Family.
Kunjan Patel, Arnaud P Giese, J M Grossheim, Rashmi S Hegde, Maria Delio, Gregory I Frolenkov

PLoS One· January 2016

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RFX transcription factors are essential for hearing in mice.
Ran Elkon, Beatrice Milon, Laura Morrison, Manan Shah, Sarath Vijayakumar, Gregory I Frolenkov

Nat Commun· October 2015

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The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing.
Qing Fang, Artur A Indzhykulian, Mirna Mustapha, Gavin P Riordan, David F Dolan, Gregory I Frolenkov

Elife· August 2015

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