Publications by authors named "H Benech"

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Intranasal delivery of dodecyl creatine ester alleviates motor deficits and increases dopamine levels in a 6-OHDA rat model of parkinsonism.
Clémence Disdier, Clara Lhotellier, Stéphanie Wagner, Emile Andriambeloson, Frédéric Théodoro

Front Aging Neurosci· July 2025

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Dodecyl creatine ester, a promising treatment to deliver creatine to neurons, achieves pharmacology efficacy in creatine transporter deficiency.
Clémence Disdier, Clara Lhotellier, Anne-Cécile Guyot, Narciso Costa, Frédéric Théodoro

Eur J Med Chem· February 2025

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Impaired brain glucose metabolism as a biomarker for evaluation of dodecyl creatine ester in creatine transporter deficiency: Insights from patient brain-derived organoids and in vivo [18F]FDG PET imaging in a mouse model.
Clémence Disdier, Amélie Soyer, Léa Broca-Brisson, Sébastien Goutal, Anne-Cécile Guyot

Neurobiol Dis· November 2024

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Dodecyl creatine ester improves cognitive function and identifies key protein drivers including KIF1A and PLCB1 in a mouse model of creatine transporter deficiency.
Aloïse Mabondzo, Rania Harati, Léa Broca-Brisson, Anne-Cécile Guyot, Narciso Costa, Henri Benech

Front Mol Neurosci· March 2023

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Evaluation of a six-probe cocktail (caffeine, tolbutamide, omeprazole, dextromethorphan, midazolam, and digoxin) approach to estimate hepatic drug detoxification capability and dosage requirements after a single oral dosing in healthy Chinese volunteers.
Seok Hwee Koo, Gaik Hong Soon, Alain Pruvost, Henri Benech, Tiing Leong Ang

Naunyn Schmiedebergs Arch Pharmacol· July 2022

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