Publications by authors named "Heba Allam"

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Design and development of potent roflumilast analogues targeting PDE-4B: selectivity and pharmacokinetic insights.
Ahmed M Moussa, Heba Abdelrasheed Allam, Ahmed A Al-Karmalawy, Abdelrahman K Salem, Radwan Alnajjar

Bioorg Chem· December 2025

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Novel chalcone 2-thiopyrimidine conjugates as dual VEGFR-2/BRAF inhibitors: design, synthesis, cytotoxicity, and molecular docking study.
Randa Atef Ibrahim Abdelaziz, Heba Abdelrasheed Allam, Ahmed Mahmoud El Kerdawy, Mahmoud Taha Abo-Elfadl, Safinaz El-Sayed Abbas

RSC Med Chem· November 2025

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GSK3B directs DNA repair choice and determines tumor response to PARP1 inhibition independent of BRCA1.
Heba S Allam, Scarlett Acklin-Wehnert, Ratan Sadhukhan, Mousumi Patra, Fen Xia

J Clin Invest· November 2025

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Design, novel one-pot green synthesis, and biological evaluation of pyrazolopyridine-congeners selectively targeting HER2+ breast cancer.
Samar M Mogheith, Heba Abdelrasheed Allam, Manal Abdel Fattah Ezzat, Ishaq Khan, Tamer E Fandy

Bioorg Chem· August 2025

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Quinolone as a Privileged Scaffold: A Brief Overview on Early Classical and Recent Advanced Synthetic Pathways, Innovative Neuroprotective Potential, and Structure-Activity Relationships.
Esraa Abdo Moustafa, Nahed Nasser Eid El-Sayed, Marwa A Fouad, Ahmed M El Kerdawy, Manal Abdel Fattah Ezzat, Heba Abdelrasheed Allam

Drug Dev Res· August 2025

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6,7-Dimethoxy-2-methyl-4-substituted quinazolines: Design, synthesis, EGFR inhibitory activity, in vitro cytotoxicity, and in silico studies.
Nermin S Saleh, Nahed N E El-Sayed, Ola A Saleh, Heba Abdelrasheed Allam, Nada M Mohamed

Eur J Med Chem· June 2025

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Gastroesophageal Reflux Disease Among Undergraduate Medical Students in Egypt: Prevalence and Risk Factors.
Ali Essa, Ahmed Nasser, Ibrahim Mohamed Noureldeen, Ibrahim Ebeid, Ahmed Ebeid, Heba Khodary Allam

Int J Gen Med· December 2024

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Neurological and neurobehavioral effects of welders in Egypt exposed to manganese containing welding fumes.
Gaafar Mohamed Abdel-Rasoul, Mahmoud El-Sayed Abu-Salem, Eman Abdel-Azeem Salem, Heba Khodary Allam, Amira Mohamed Abdel-Monaem

Int Arch Occup Environ Health· September 2024

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Design, synthesis, and biological evaluation of dinaciclib and CAN508 hybrids as CDK inhibitors.
Dana M Odeh, Heba Abdelrasheed Allam, Fady Baselious, Walaa R Mahmoud, Mohanad M Odeh

Drug Dev Res· May 2024

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Exploring new quinazolin-4(3H)-one derivatives as CDK2 inhibitors: Design, synthesis, and anticancer evaluation.
Basant T Ibrahim, Heba Abdelrasheed Allam, Nehad M El-Dydamony, Marwa A Fouad, Eman R Mohammed

Drug Dev Res· April 2024

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Design and synthesis of some new benzoylthioureido benzenesulfonamide derivatives and their analogues as carbonic anhydrase inhibitors.
Khulood H Oudah, Walaa R Mahmoud, Fadi M Awadallah, Azza T Taher, Safinaz E-S Abbas, Heba Abdelrasheed Allam

J Enzyme Inhib Med Chem· December 2023

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Effect of hydrophobic extension of aryl enaminones and pyrazole-linked compounds combined with sulphonamide, sulfaguanidine, or carboxylic acid functionalities on carbonic anhydrase inhibitory potency and selectivity.
Heba Abdelrasheed Allam, Mohamed E Albakry, Walaa R Mahmoud, Alessandro Bonardi, Shaimaa A Moussa

J Enzyme Inhib Med Chem· December 2023

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Design and synthesis of certain 7-Aryl-2-Methyl-3-Substituted Pyrazolo{1,5-a}Pyrimidines as multikinase inhibitors.
Mustafa A Al-Qadhi, Heba Abdelrasheed Allam, Samar H Fahim, Tawfeek A A Yahya, Fatma A F Ragab

Eur J Med Chem· December 2023

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Design, synthesis, in vitro, and in vivo evaluation of novel phthalazinone-based derivatives as promising acetylcholinesterase inhibitors for treatment of Alzheimer's disease.
Manal Abdel Fattah Ezzat, Sara Mohamed Abdelhamid, Marwa A Fouad, Hatem A Abdel-Aziz, Heba Abdelrasheed Allam

Drug Dev Res· September 2023

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Design and synthesis of some new benzoylthioureido phenyl derivatives targeting carbonic anhydrase enzymes.
Mazin A A Najm, Walaa R Mahmoud, Azza T Taher, Safinaz E-S Abbas, Fadi M Awadallah, Heba Abdelrasheed Allam

J Enzyme Inhib Med Chem· December 2022

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Natural inspired ligustrazine-based SLC-0111 analogues as novel carbonic anhydrase inhibitors.
Diaaeldin M Elimam, Wagdy M Eldehna, Rofaida Salem, Alessandro Bonardi, Alessio Nocentini, Heba Abdelrasheed Allam

Eur J Med Chem· January 2022

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Respiratory health disorders among workers in some Egyptian welding enterprises.
Gaafar M Abdel-Rasoul, Mahmoud El-Sayed Abu-Salem, Eman Abdel-Azeem Salem, Faten E Younis, Amira M Abdel-Monaem, Heba K Allam

Toxicol Ind Health· January 2022

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Nanomolar potency of imidazo[2,1-b]thiazole analogs as indoleamine 2,3-dioxygenase inhibitors.
Menna A Ewida, Heba A Ewida, Mahmoud S Ahmed, Heba Abdelrasheed Allam, Ramzia I ElBagary

Arch Pharm (Weinheim)· November 2021

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Effects of remote virtual work environment during COVID-19 pandemic on technostress among Menoufia University Staff, Egypt: a cross-sectional study.
Hala Marawan Gabr, Shaimaa Sherif Soliman, Heba Khodary Allam, Shaimaa Yaihya Abdel Raouf

Environ Sci Pollut Res Int· October 2021

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3-Methyl-imidazo[2,1-b]thiazole derivatives as a new class of antifolates: Synthesis, in vitro/in vivo bio-evaluation and molecular modeling simulations.
Menna A Ewida, Heba A Ewida, Mahmoud S Ahmed, Heba Abdelrasheed Allam, Ramzia I ElBagary

Bioorg Chem· October 2021

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Work schedule and substance abuse in vocational students.
Shaimaa Sherif Soliman, Heba Khodary Allam, Nagwa Mahmoud Habib, Ayat Roushdy Abdallah, Omayma M Hassan

J Public Health Res· August 2021

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Genotoxicity linked to occupational exposure in uranium mine workers: Granzyme B and apoptotic changes.
Islam El-Garawani, Heba Khodary Allam, Yasser A Shehata, Khaldoun Fadel, Ahmed El Kattan

Environ Sci Pollut Res Int· July 2021

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Workaholism, sleep disorders, and potential e-learning impacts among Menoufia university staff during COVID-19 pandemic.
Heba Khodary Allam, Mai Salah Helmy, Aziza Saad El Badry, Faten Ezzelarab Younis

J Public Health Res· June 2021

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Secondhand tobacco smoke, does it have an impact on the neurobehavioral performance of the exposed children?
Eman Abdel-Azeem Salem, Hala Mohammed Saheen, Heba Khodary Allam

Environ Sci Pollut Res Int· December 2020

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PARP1-DNMT1-CTCF complex and the apoptotic-induced factor mRNA expressions in workers occupationally exposed to benzene.
Mona Salah El-Din Habieb, Faten Ezzelarab Younis, Manal Safan, Heba Khodary Allam

Environ Sci Pollut Res Int· June 2020

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