Publications by authors named "Hitoshi Okazawa"

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Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice.
Hiroki Shiwaku, Shingo Katayama, Kanoh Kondo, Yuri Nakano, Hikari Tanaka, Yuki Yoshioka, Kyota Fujita, Haruna Tamaki, Hironao Takebayashi, Omi Terasaki

Cell Rep Med· April 2022

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Intestinal CD4CD8αβTCRαβ T cells function as tolerogenic antigen presenting cells in mice.
Yasuhiro Nemoto, Ryo Morikawa, Yuki Yonemoto, Shohei Tanaka, Yuria Takei, Hitoshi Okazawa

Nat Commun· August 2025

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PQBP1-dependent alternative RNA splicing underlies high calorie diet-induced cognitive impairment.
Yong Huang, Hidenori Homma, Xigui Chen, Hikari Tanaka, Kyota Fujita, Hitoshi Okazawa

bioRxiv· June 2025

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PQBP3/NOL7 is an intrinsically disordered protein.
Hidenori Homma, Kien Xuan Ngo, Yuki Yoshioka, Hikari Tanaka, Maiko Inotsume, Hitoshi Okazawa

Biochem Biophys Res Commun· December 2024

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Loss of function of VCP/TER94 causes neurodegeneration.
Kohei Tsumaki, Christian J F Bertens, Minoru Nakayama, Saya Kato, Yuki Jonao, Hitoshi Okazawa

Dis Model Mech· December 2024

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PQBP3 prevents senescence by suppressing PSME3-mediated proteasomal Lamin B1 degradation.
Yuki Yoshioka, Yong Huang, Xiaocen Jin, Kien Xuan Ngo, Tomohiro Kumaki, Hitoshi Okazawa

EMBO J· September 2024

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Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage.
Hidenori Homma, Yuki Yoshioka, Kyota Fujita, Shinichi Shirai, Yuka Hama, Hitoshi Okazawa

Commun Biol· April 2024

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Necrosis Links Neurodegeneration and Neuroinflammation in Neurodegenerative Disease.
Hidenori Homma, Hikari Tanaka, Kyota Fujita, Hitoshi Okazawa

Int J Mol Sci· March 2024

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AAV-mediated editing of PMP22 rescues Charcot-Marie-Tooth disease type 1A features in patient-derived iPS Schwann cells.
Yuki Yoshioka, Juliana Bosso Taniguchi, Hidenori Homma, Takuya Tamura, Kyota Fujita, Hitoshi Okazawa

Commun Med (Lond)· November 2023

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Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A Fischer, Kyota Fujita, Hitoshi Okazawa

Cell· October 2023

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Mutant α-synuclein propagates via the lymphatic system of the brain in the monomeric state.
Kyota Fujita, Hidenori Homma, Meihua Jin, Yuki Yoshioka, Xiaocen Jin, Hitoshi Okazawa

Cell Rep· August 2023

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Analyzing schizophrenia-related phenotypes in mice caused by autoantibodies against NRXN1α in schizophrenia.
Hiroki Shiwaku, Shingo Katayama, Mengxuan Gao, Kanoh Kondo, Yuri Nakano, Hitoshi Okazawa

Brain Behav Immun· July 2023

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PQBP5/NOL10 maintains and anchors the nucleolus under physiological and osmotic stress conditions.
Xiaocen Jin, Hikari Tanaka, Meihua Jin, Kyota Fujita, Hidenori Homma, Hitoshi Okazawa

Nat Commun· January 2023

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[Recommendations (Proposal) for promoting research for overcoming neurological diseases 2020].
Hideki Mochizuki, Masashi Aoki, Kensuke Ikenaka, Haruhisa Inoue, Takeshi Iwatsubo, Hitoshi Okazawa

Rinsho Shinkeigaku· June 2022

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[Recommendations (Proposal) for promoting research for overcoming neurological diseases 2020].
Hideki Mochizuki, Masashi Aoki, Kensuke Ikenaka, Haruhisa Inoue, Takeshi Iwatsubo, Hitoshi Okazawa

Rinsho Shinkeigaku· June 2022

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PQBP1: The Key to Intellectual Disability, Neurodegenerative Diseases, and Innate Immunity.
Hikari Tanaka, Hitoshi Okazawa

Int J Mol Sci· June 2022

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[Career Path and Leadership of Basic Researchers Based on Clinical Medicine].
Hitoshi Okazawa

Brain Nerve· January 2022

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[Recommendations (Proposal) for promoting research for overcoming neurological diseases 2020].
Hideki Mochizuki, Masashi Aoki, Kensuke Ikenaka, Haruhisa Inoue, Takeshi Iwatsubo, Hitoshi Okazawa

Rinsho Shinkeigaku· November 2021

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Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation.
Meihua Jin, Hiroki Shiwaku, Hikari Tanaka, Takayuki Obita, Sakurako Ohuchi, Hitoshi Okazawa

Nat Commun· November 2021

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HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer's disease pathology.
Hikari Tanaka, Kanoh Kondo, Kyota Fujita, Hidenori Homma, Kazuhiko Tagawa, Hitoshi Okazawa

Commun Biol· October 2021

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Hepta-Histidine Inhibits Tau Aggregation.
Kanoh Kondo, Teikichi Ikura, Hikari Tanaka, Kyota Fujita, Sumire Takayama, Hitoshi Okazawa

ACS Chem Neurosci· August 2021

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Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysis.
Meihua Jin, Xiaocen Jin, Hidenori Homma, Kyota Fujita, Hikari Tanaka, Hitoshi Okazawa

Commun Biol· August 2021

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DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis.
Hidenori Homma, Hikari Tanaka, Meihua Jin, Xiaocen Jin, Yong Huang, Hitoshi Okazawa

Life Sci Alliance· July 2021

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Intracellular amyloid hypothesis for ultra-early phase pathology of Alzheimer's disease.
Hitoshi Okazawa

Neuropathology· April 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Hitoshi Okazawa

Autophagy· January 2021

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