Publications by authors named "Howard Worman"

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Prelamin A Does Not Promote Atherosclerosis or Vascular Smooth Muscle Loss.
Yuexia Wang, Leroy C Joseph, Cecilia Östlund, George Kuriakose, Wei Hsu, Howard J Worman

bioRxiv· September 2025

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Nesprin-2 contains BH3-like motifs that can promote cell death.
Hila Zohar, Amit Kessel, Liora Lindenboim, Dang Nguyen, Nir Ben-Tal, Howard J Worman

Cell Death Discov· June 2025

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The nucleus activates mechano-responsiveness via FHOD-associated LINC complexes.
Susumu Antoku, Leroy C Joseph, Prachi Dabhade, B Xiaokan Zhang, Chyuan-Sheng Lin, Howard J Worman

bioRxiv· June 2025

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Apoptosis-induced translocation of nesprin-2 from the nuclear envelope to mitochondria is associated with mitochondrial dysfunction.
Hila Zohar, Liora Lindenboim, Oren Gozlan, Gregg G Gundersen, Howard J Worman

Nucleus· December 2024

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mTOR Inhibition Prolongs Survival and Has Beneficial Effects on Heart Function After Onset of Lamin A/C Gene Mutation Cardiomyopathy in Mice.
Wei Wu, Qi Jin, Cecilia Östlund, Kurenai Tanji, Ji-Yeon Shin, Howard J Worman

Circ Heart Fail· April 2024

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Dynamic regulation of hepatic lipid metabolism by torsinA and its activators.
Antonio Hernandez-Ono, Yi Peng Zhao, John W Murray, Cecilia Östlund, Michael J Lee, Howard J Worman

JCI Insight· February 2024

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Long live lamins.
Qi Jin, Howard J Worman

J Cell Biol· January 2024

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LINC complex protein nesprin-2 has pro-apoptotic activity via Bcl-2 family proteins.
Liora Lindenboim, Hila Zohar, Gregg G Gundersen, Howard J Worman, Reuven Stein

Cell Death Discov· January 2024

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Prelamin A and ZMPSTE24 in premature and physiological aging.
Howard J Worman, Susan Michaelis

Nucleus· December 2023

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The diagnostic yield of exome sequencing in liver diseases from a curated gene panel.
Xiao-Fei Kong, Kelsie Bogyo, Sheena Kapoor, Patrick R Shea, Emily E Groopman, Howard J Worman

Sci Rep· December 2023

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Functional interaction of torsinA and its activators in liver lipid metabolism.
Antonio Hernandez-Ono, Yi Peng Zhao, John W Murray, Cecilia Östlund, Michael J Lee, Howard J Worman

bioRxiv· July 2023

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Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets.
Cecilia Östlund, Antonio Hernandez-Ono, Samantha J Turk, William T Dauer, Henry N Ginsberg, Howard J Worman

J Lipid Res· October 2022

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Vibration-controlled Transient Elastography for Assessment of Liver Fibrosis at a USA Academic Medical Center.
Max Shen, Anna Lee, Jay H Lefkowitch, Howard J Worman

J Clin Transl Hepatol· April 2022

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Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice.
Yuexia Wang, Khurts Shilagardi, Trunee Hsu, Kamsi O Odinammadu, Takamitsu Maruyama, Howard J Worman

Proc Natl Acad Sci U S A· March 2022

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Molecular Pathology of Laminopathies.
Ji-Yeon Shin, Howard J Worman

Annu Rev Pathol· January 2022

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Jaundice in patients with COVID-19.
Joshua M Bender, Howard J Worman

JGH Open· October 2021

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The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies.
Nicolas Vignier, Maria Chatzifrangkeskou, Luca Pinton, Hugo Wioland, Thibaut Marais, Howard J Worman

Cell Rep· August 2021

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Coronavirus Disease 2019 and Liver Injury: A Retrospective Analysis of Hospitalized Patients in New York City.
Joshua M Bender, Howard J Worman

J Clin Transl Hepatol· August 2021

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Protein structural and mechanistic basis of progeroid laminopathies.
Agathe Marcelot, Howard J Worman, Sophie Zinn-Justin

FEBS J· May 2021

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A lamin A/C variant causing striated muscle disease provides insights into filament organization.
Rafael Kronenberg-Tenga, Meltem Tatli, Matthias Eibauer, Wei Wu, Ji-Yeon Shin, Howard J Worman

J Cell Sci· March 2021

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Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation.
Haikel Dridi, Wei Wu, Steven R Reiken, Rachel M Ofer, Yang Liu, Howard J Worman

Hum Mol Genet· February 2021

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Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins.
Liora Lindenboim, Dan Grozki, Ayelet R Amsalem-Zafran, Aida Peña-Blanco, Gregg G Gundersen, Howard J Worman

Cell Death Discov· September 2020

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The nuclear envelope: target and mediator of the apoptotic process.
Liora Lindenboim, Hila Zohar, Howard J Worman, Reuven Stein

Cell Death Discov· April 2020

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ERK1/2 Phosphorylation of FHOD Connects Signaling and Nuclear Positioning Alternations in Cardiac Laminopathy.
Susumu Antoku, Wei Wu, Leroy C Joseph, John P Morrow, Howard J Worman

Dev Cell· December 2019

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Emery-Dreifuss muscular dystrophy: focal point nuclear envelope.
Antoine Muchir, Howard J Worman

Curr Opin Neurol· October 2019

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