Publications by authors named "Ian R. Hart"

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Corrigendum: Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes.
Rachel Barrow-McGee, Naoki Kishi, Carine Joffre, Ludovic Ménard, Alexia Hervieu, Ian R Hart

Nat Commun· July 2016

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Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes.
Rachel Barrow-McGee, Naoki Kishi, Carine Joffre, Ludovic Ménard, Alexia Hervieu, Ian R Hart

Nat Commun· June 2016

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RhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cells.
Ningfeng Fiona Li, Emilios Gemenetzidis, Francis J Marshall, Derek Davies, Yongwei Yu, Ian R Hart

PLoS One· September 2014

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Therapeutic targeting of integrin αvβ6 in breast cancer.
Kate M Moore, Gareth J Thomas, Stephen W Duffy, Jane Warwick, Rhian Gabe, Ian R Hart

J Natl Cancer Inst· August 2014

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Functional analysis of a breast cancer-associated FGFR2 single nucleotide polymorphism using zinc finger mediated genome editing.
Luisa J Robbez-Masson, Csaba Bödör, J Louise Jones, Helen C Hurst, Jude Fitzgibbon, Ian R Hart

PLoS One· July 2014

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Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence.
Michael D Allen, Gareth J Thomas, Sarah Clark, Marwa M Dawoud, Sabarinath Vallath, Ian R Hart

Clin Cancer Res· January 2014

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FAK-heterozygous mice display enhanced tumour angiogenesis.
Vassiliki Kostourou, Tanguy Lechertier, Louise E Reynolds, Delphine M Lees, Marianne Baker, Ian R Hart

Nat Commun· December 2013

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Combined fiber modifications both to target α(v)β(6) and detarget the coxsackievirus-adenovirus receptor improve virus toxicity profiles in vivo but fail to improve antitumoral efficacy relative to adenovirus serotype 5.
Lynda Coughlan, Sabari Vallath, Alena Gros, Marta Giménez-Alejandre, N Van Rooijen, Ian R Hart

Hum Gene Ther· September 2012

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Non-junctional human desmoglein 3 acts as an upstream regulator of Src in E-cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris.
Siu Man Tsang, Louise Brown, Kuang Lin, Li Liu, Kim Piper, Ian R Hart

J Pathol· May 2012

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Proteome of formalin-fixed paraffin-embedded pancreatic ductal adenocarcinoma and lymph node metastases.
Kalnisha Naidoo, Richard Jones, Branko Dmitrovic, Nilukshi Wijesuriya, Hemant Kocher, Ian R Hart

J Pathol· April 2012

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β3-integrin is required for differentiation in OC-2 cells derived from mammalian embryonic inner ear.
Ivan Brunetta, Stefano O Casalotti, Ian R Hart, Andrew Forge, Louise E Reynolds

BMC Cell Biol· March 2012

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Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression.
Fieke E M Froeling, Christine Feig, Claude Chelala, Richard Dobson, Charles E Mein, Ian R Hart

Gastroenterology· October 2011

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Editorial: Special section on "site-specific metastasis".
Heike Allgayer, Ian R Hart

Int J Cancer· June 2011

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A direct role for Met endocytosis in tumorigenesis.
Carine Joffre, Rachel Barrow, Ludovic Ménard, Véronique Calleja, Ian R Hart

Nat Cell Biol· June 2011

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Clinical and functional significance of α9β1 integrin expression in breast cancer: a novel cell-surface marker of the basal phenotype that promotes tumour cell invasion.
Michael D Allen, Reza Vaziri, Michael Green, Claude Chelala, Adam R Brentnall, Ian R Hart

J Pathol· April 2011

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Stromal features are predictive of disease mortality in oral cancer patients.
Daniel Marsh, Krishna Suchak, Karwan A Moutasim, Sabarinath Vallath, Colin Hopper, Ian R Hart

J Pathol· March 2011

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Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis.
Karwan A Moutasim, Veronika Jenei, Karen Sapienza, Daniel Marsh, Paul H Weinreb, Ian R Hart

J Pathol· February 2011

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Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src.
Siu Man Tsang, Li Liu, Muy-Teck Teh, Ann Wheeler, Richard Grose, Ian R Hart

PLoS One· December 2010

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High-resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin alphavbeta6.
Antonio Saha, David Ellison, Gareth J Thomas, Sabarinath Vallath, Stephen J Mather, Ian R Hart

J Pathol· September 2010

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Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF.
Rita Graça da Silva, Bernardo Tavora, Stephen D Robinson, Louise E Reynolds, Charles Szekeres, Ian R Hart

Am J Pathol· September 2010

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Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome.
Louise E Reynolds, Alan R Watson, Marianne Baker, Tania A Jones, Gabriela D'Amico, Ian R Hart

Nature· June 2010

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New evidence for tumour embolism as a mode of metastasis.
Ian R Hart

J Pathol· November 2009

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Loss-of-function FERMT1 mutations in kindler syndrome implicate a role for fermitin family homolog-1 in integrin activation.
Joey E Lai-Cheong, Maddy Parsons, Akio Tanaka, Siegfried Ussar, Andrew P South, Ian R Hart

Am J Pathol· October 2009

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Organotypic culture model of pancreatic cancer demonstrates that stromal cells modulate E-cadherin, beta-catenin, and Ezrin expression in tumor cells.
Fieke E M Froeling, Tariq A Mirza, Roger M Feakins, Angela Seedhar, George Elia, Ian R Hart

Am J Pathol· August 2009

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In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery.
Lynda Coughlan, Sabari Vallath, Antonio Saha, Magdalena Flak, Iain A McNeish, Ian R Hart

J Virol· July 2009

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